Results 21 to 30 of about 19,855 (219)

Analysis and characterization of mouse monoclonal antibodies reactive to Chikungunya virus (CHIKV) [PDF]

International Journal of Infectious Diseases, 2010
occurring in 1984). However, plague has made an astonishing comeback in the last decade. Methods: n/a. Results: After a silence of 50 years, an outbreak of bubonic plague suddenly occurred close to Oran in Algeria, in June 2003. Eighteen bubonic cases were identified, and Yersinia pestis was isolated from 6 patients.
Giada Rossini, A. Pierro, Paolo Gaibani, Francesca Cavrini, M.P. Landini, Vittorio Sambri   +5 more
openalex   +3 more sources

Seroprevalence of Chikungunya virus (CHIKV) infection on Lamu Island, Kenya, October 2004.

The American Journal of Tropical Medicine and Hygiene, 2008
An outbreak of Chikungunya virus (CHIKV) disease associated with high fever and severe protracted arthralgias was detected in Lamu, Kenya, peaking in July 2004. At least 1,300 cases were documented. We conducted a seroprevalence study to define the magnitude of transmission on Lamu Island. We conducted a systematic cross-sectional survey.
Kibet Sergon, C. Onyango, R. Breiman, V. Ofula, S. Bedno, Limbaso S. Konongoi, H. Burke, J. Konde, R. Sang, Athman M. Dumilla, Rosalia Kalani, M. K. Njenga, C. Njuguna   +12 more
semanticscholar   +3 more sources

2888. Safety and Immunogenicity of an Adjuvanted Chikungunya Virus (CHIKV) Virus-like Particle (VLP) Based Vaccine in Two Pivotal Phase 3 Trials, ≥12 Years of Age [PDF]

Open Forum Infect Dis, 2023
Jason S. Richardson, Debbie Anderson, Jason Mendy, Sufia Muhammad, Lauren C. Tindale, Tobi Loreth, Sarah Royalty Tredo, Victoria Jenkins, Patrick Ajiboye, Lisa Bedell   +9 more
europepmc   +3 more sources

Large-scale outbreak of Chikungunya virus infection in Thailand, 2018-2019.

PLoS ONE, 2021
Between 2018 and 2019, the incidence of chikungunya was approximately 15,000 cases across 60 provinces in Thailand. Here, the clinical presentations in chikungunya, emergent pattern, and genomic diversity of the chikungunya virus (CHIKV) causing this ...
Sarawut Khongwichit, Jira Chansaenroj, Thanunrat Thongmee, Saovanee Benjamanukul, Nasamon Wanlapakorn, Chintana Chirathaworn, Yong Poovorawan   +6 more
doaj   +2 more sources

A booster regime of liposome-delivered live-attenuated CHIKV vaccine RNA genome protects against chikungunya virus disease in mice

Vaccine, 2023
Mosquito-transmitted chikungunya virus (CHIKV) is the causal pathogen of CHIKV disease and is responsible for global epidemics of arthritic disease. CHIKV infection can lead to severe chronic and debilitating arthralgia, significantly impacting patient mobility and quality of life.
Shambhavi Rao, Eranga Abeyratne, Joseph R. Freitas, Chenying Yang, Kothila Tharmarajah, Helen Mostafavi, Xiang Liu, Mehfuz Zaman, Suresh Mahalingam, Ali Zaid, Adam Taylor   +10 more
openalex   +4 more sources

Detection of Chikungunya virus (CHIKV) in urine of infected mice: a Potential Non-invasive Diagnostic Tool for CHIKV

Journal of Infectious Diseases & Therapy, 2015
Background: The reemergence of Chikungunya virus (CHIKV) infection and the spread of the virus throughout the world call for a fast, reliable, and improved laboratory diagnostic procedures. The aim of this study was to determine if CHIKV genome is present in other body fluids besides plasma as a tool for developing non-invasive diagnostic method ...
Jones Ph, Okeoma CM
openalex   +2 more sources

A retrospective investigation for the seroprevalence of Chikungunya virus and its co-existence with Dengue virus in Pakistani population, 2014–2015 [PDF]

Scientific Reports
Dengue and Chikungunya are caused by the same vectors, Aedes aegypti and Aedes albopictus. Both mosquitoes are endemic in Pakistan, and various parts of the country experienced outbreaks of Dengue virus over the past decades.
Darakhshan Guhar, Kiran A. Qadir, Fiza Khan, Shafqat F. Rehmani, Sayyada G. Nadeem   +4 more
doaj   +2 more sources

Chikungunya Virus: Priority Pathogen or Passing Trend?

Vaccines, 2023
Chikungunya virus (CHIKV) is considered a priority pathogen and a major threat to global health. While CHIKV infections may be asymptomatic, symptomatic patients can develop chikungunya fever (CHIKF) characterized by severe arthralgia which often ...
Gerardo Montalvo Zurbia-Flores, Arturo Reyes-Sandoval, Young Chan Kim   +2 more
doaj   +2 more sources

Nanotechnology: A promising approach of antiviral treatments against chikungunya virus (CHIKV)

Journal of Scientific and Innovative Research, 2018
Following its emergence in Africa, spread to the Indian Ocean islands in 2006, and occurrences in regions of the world where it hadn’t been reported in the past, Chikungunya has become an emerging public health concern in many countries. The past outbreaks of the chikungunya virus (CHIKV) have caused widespread morbidity and mortality.
Rishikesh Kumar, Ganesh Chandra Sahoo, Bhawna Verma, Aparna Ramachandran, Mohammad Yousuf Ansari, Krishna Pandey, VNR Das, RK Topno, Major Madhukar, Pradeep Das   +9 more
openalex   +2 more sources

Synthesis and Anti-Chikungunya Virus (CHIKV) Activity of Novel 1,4-Naphthoquinone Sulfonamide and Sulfonate Ester Derivatives

Journal of the Brazilian Chemical Society, 2022
Chikungunya virus (CHIKV) is a re-emerging disease caused by an alphavirus of the Togaviridae family. Since its first description in 1952, the disease has spread worldwide, affecting populations in both tropical and temperate countries. To date, there is no licensed vaccine or specific pharmacological treatment.
Paulo Pacheco, Daniel Tadeu Gomes Gonzaga, Claudio Cesar Cirne-Santos, Caroline de Souza Barros, Max Gomes, Rafaela Gomes, Mariana de Castro Gonçalves, Vı́tor F. Ferreira, Vitor Won‐Held Rabelo, Paula Alvarez Abreu, Robson Xavier Faria, Gabriel de Resende, David Rodrigues da Rocha, Izabel Christina Nunes de Palmer Paixão, Fernando de Carvalho da Silva   +14 more
openalex   +4 more sources