Results 51 to 60 of about 15,418 (233)

Recent Progress in Vaccine Development Against Chikungunya Virus

Frontiers in Microbiology, 2019
Chikungunya fever (CHIKF) is an acute infectious disease that is mediated by the mosquito-transmitted chikungunya virus (CHIKV). People infected with CHIKV may experience high fever, severe joint pain, skin rash, and headache.
Shan Gao, Siqi Song, Siqi Song, Leiliang Zhang   +3 more
doaj   +1 more source

Low chikungunya virus seroprevalence two years after emergence in Fiji

International Journal of Infectious Diseases, 2020
Objectives: In Fiji, autochthonous chikungunya virus (CHIKV) infection was first detected in March 2015. In a previous serosurvey conducted during October–November 2015, we reported a prevalence of anti-CHIKV IgG antibodies of 0.9%. In the present study,
Maite Aubry, Mike Kama, Alasdair D. Henderson, Anita Teissier, Jessica Vanhomwegen, Teheipuaura Mariteragi-Helle, Tuterarii Paoaafaite, Jean-Claude Manuguerra, Ketan Christi, Conall H. Watson, Colleen L. Lau, Adam J. Kucharski, Van-Mai Cao-Lormeau   +12 more
doaj   +1 more source

Wolbachia and arbovirus inhibition in mosquitoes [PDF]

, 2013
Wolbachia is a maternally inherited intracellular bacteria that can manipulate the reproduction of their insect hosts, and cytoplasmic incompatibility allows them to spread through mosquito populations.
Sinkins, Steven P.
core   +1 more source

Chikungunya Virus (CHIKV): The Novel Challenge to the Healthcare System

Pakistan Journal of Medical & Health Sciences
Chikungunya (CHIKV) is a viral illness transmitted by mosquitoes, characterized by fever and intense arthralgia. It is induced by a ribonucleic acid (RNA) virus classified within the alphavirus genus of the Togaviridae family1. The word “chikungunya” originates from a phrase in the Kimakonde phrases of southern the Republic of Tanzania, indicating “to ...
Pir eh, Iffat Jamal, Syed Zulfiqar Ali Shah, Muqadas Fatima, Farheen Qadeer, M. A. Ali   +5 more
openalex   +3 more sources

A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs [PDF]

, 2016
Chikungunya virus (CHIKV) is a globally spreading alphavirus against which there is no commercially available vaccine or therapy. Here we use a genome-wide siRNA screen to identify 156 proviral and 41 antiviral host factors affecting CHIKV replication ...
Berre, Stefano, Bracher, Franz, Braun, Peter, Couderc, Thérèsr, Gangneux, Nicolas, Karlas, Alexander, Karo-Astover, Liis, Klemm, Uwe, Lecuit, Marc, Merits, Andres, Meyer, Michael, Meyer, Thomas F., Raftery, Martin, Schönrich, Günther, Varjak, Margus, Weege, Friderike, Wurzlbauer, Anne   +16 more
core   +5 more sources

Chikungunya infection and horner syndrome

IDCases, 2018
We describe an infant with Chikungunya virus (CHIKV) infection who developed Horner syndrome. The infant had diagnostic confirmation of CHIKV infection by IgM-ELISA positive in serum and cerebrospinal fluid, and clinical signs of Horner syndrome ...
Lucas Victor Alves, Filipe Marinho Pinheiro da Câmara, Mayara Batista Granha, Alfredo Meneses Neto, Bezerra Alves, JG   +4 more
doaj   +1 more source

Epidemiologic and clinical investigations during a chikungunya outbreak in Rio Grande do Norte State, Brazil.

PLoS ONE, 2020
The first autochthonous case of chikungunya virus (CHIKV) infection in Brazil was in September 2014 in the State of Amapá, and from there it rapidly spread across the country.
Joelma D Monteiro, Joanna Gardel Valverde, Ingryd Camara Morais, Cassio Ricardo de Medeiros Souza, João Ciro Fagundes Neto, Marília Farias de Melo, Yasmin Mesquita Nascimento, Brenda Elen Bizerra Alves, Leandro Gurgel de Medeiros, Hannaly W Bezerra Pereira, Anne Aline Pereira de Paiva, Diego G Teixeira, Márcia Cristina Bernardo de Melo Moura, Alessandre de Medeiros Tavares, José Veríssimo Fernandes, Selma M B Jeronimo, Josélio M G Araújo   +16 more
doaj   +1 more source

Transient transmission of Chikungunya virus in Singapore exemplifies successful mitigation of severe epidemics in a vulnerable population

International Journal of Infectious Diseases, 2021
Objectives: Singapore experienced two major outbreaks of chikungunya in 2008-09 and 2013-14. Despite repeated virus introductions, fresh local outbreaks have not emerged after 2014.
Hapuarachchige Chanditha Hapuarachchi, Wing-Yan Wong, Carmen Koo, Wei-Ping Tien, Gladys Yeo, Jayanthi Rajarethinam, Eugene Tan, Suzanna Chiang, Chee-Seng Chong, Cheong-Huat Tan, Li-Kiang Tan, Lee-Ching Ng   +11 more
doaj   +1 more source

Comodulation of Dengue and Chikungunya Virus Infection During a Coinfection Scenario in Human Cell Lines

Frontiers in Cellular and Infection Microbiology, 2022
The Dengue virus (DENV) and Chikungunya virus (CHIKV) are the arboviruses that pose a threat to global public health. Coinfection and antibody-dependent enhancement are major areas of concern during DENV and CHIKV infections, which can alter the clinical
Debjani Taraphdar, Bharati Singh, Bharati Singh, Sabyasachi Pattanayak, Avula Kiran, Avula Kiran, Poornima Kokavalla, Mohd. Faraz Alam, Mohd. Faraz Alam, Gulam Hussain Syed   +9 more
doaj   +1 more source

The interferon-stimulated gene IFITM3 restricts infection and pathogenesis of arthritogenic and encephalitic alphaviruses [PDF]

, 2016
Host cells respond to viral infections by producing type I interferon (IFN), which induces the expression of hundreds of interferon-stimulated genes (ISGs).
Diamond, Michael S, Farzan, Michael, Gorman, Matthew J, Hyde, Jennifer L, Poddar, Subhajit   +4 more
core   +2 more sources