Emerging Infectious Diseases, 2022 To determine the extent of exposure to Zika virus (ZIKV) and chikungunya virus (CHIKV) in Jamaica, we collected serum from 584 pregnant women during 2017–2019. We found that 15.6% had antibodies against ZIKV and 83.6% against CHIKV.
Joshua J. Anzinger +17 more
doaj +1 more source
Transmission dynamics of the ongoing chikungunya outbreak in Central Italy. From coastal areas to the metropolitan city of Rome, summer 2017 [PDF]
, 2017 A large chikungunya outbreak is ongoing in Italy, with a main cluster in the Anzio coastal municipality. With preliminary epidemiological data, and a transmission model using mosquito abundance and biting rates, we estimated the basic reproduction number
Caputo, Beniamino +8 more
core +2 more sources
Kinetic analysis of mouse brain proteome alterations following chikungunya virus infection before and after appearance of clinical symptoms [PDF]
, 2014 Recent outbreaks of Chikungunya virus (CHIKV) infection have been characterized by an increasing number of severe cases with atypical manifestations including neurological complications.
Almeras, L. (Lionel) +10 more
core +18 more sources
Antagonism of the Sodium-Potassium ATPase Impairs Chikungunya Virus Infection
mBio, 2016 Chikungunya virus (CHIKV) is a reemerging alphavirus that has caused epidemics of fever, arthralgia, and rash worldwide. There are currently no licensed vaccines or antiviral therapies available for the prevention or treatment of CHIKV disease.
Alison W. Ashbrook +7 more
doaj +1 more source
Chikungunya virus: A general overview [PDF]
, 2015 Chikungunya virus (CHIKV) is a re-emerging mosquito borne alphavirus responsible for the recent outbreak in the Americas. Immunologically naïve population in the Americas favors the spread of epidemics.
Farfán Ale, José Arturo +4 more
core +1 more source
Development of Neutralization Assay Using an eGFP Chikungunya Virus
Viruses, 2016 Chikungunya virus (CHIKV), a member of the Alphavirus genus, is an important human emerging/re-emerging pathogen. Currently, there are no effective antiviral drugs or vaccines against CHIKV infection. Herein, we construct an infectious clone of CHIKV and
Cheng-Lin Deng +11 more
doaj +1 more source
Effectiveness of CHIKV vaccine VLA1553 demonstrated by passive transfer of human sera
JCI Insight, 2022 Chikungunya virus (CHIKV) is a reemerging mosquito-borne alphavirus responsible for numerous outbreaks. Chikungunya can cause debilitating acute and chronic disease.
Pierre Roques +12 more
doaj +1 more source
Chikungunya Immunopathology as It Presents in Different Organ Systems
Viruses, 2022 Chikungunya virus (CHIKV) is currently an urgent public health problem as high morbidity from the virus leaves populations with negative physical, social, and economic impacts.
Elizabeth M. Traverse +5 more
doaj +1 more source
The interferon-induced exonuclease ISG20 exerts antiviral activity through upregulation of type I interferon response proteins [PDF]
, 2018 The host immune responses to infection lead to the production of type I interferon (IFN), and the upregulation of interferon-stimulated genes (ISGs) reduces virus replication and virus dissemination within a host.
Diamond, Michael S +6 more
core +2 more sources
Extensive evolution analysis of the global chikungunya virus strains revealed the origination of CHIKV epidemics in Pakistan in 2016 [PDF]
Virologica Sinica, 2017 Chikungunya virus (CHIKV) is a mosquito-borne virus that causes epidemics widely in the world especially in the tropical and subtropical regions. Phylogenetic analysis has found that the CHIKV lineages were associated with the spatial and temporal distributions, which were related to the virus adaption to the major mosquito species and their ...
Junming Shi +10 more
openalex +4 more sources