Results 71 to 80 of about 19,855 (219)
Frontiers in Pediatrics, 2022 IntroductionIn a low-income setting with simultaneous presence of Dengue virus, Zika virus, and Chikungunya virus (CHIKV) in the same region, the difficulty of establishing a clinical diagnosis when the molecular test is not a possibility.
Patrícia Damião Gomes +7 more
doaj +1 more source
The Tetraspanin CD81 Is a Host Factor for Chikungunya Virus Replication
mBio, 2022 In this study, we discover the tetraspanin CD81 as a host factor for the globally emerging chikungunya virus and related alphaviruses. We show that CD81 promotes replication of viral genomes in human and mouse cells, while virus entry into cells is ...
Lisa Lasswitz +9 more
semanticscholar +1 more source
Heliyon, 2023 Cases of dengue and chikungunya fever are escalating all over India. Both viruses share a common vector, the “Aedes” mosquito. Due to similar clinical symptoms, both the dengue (DENV) and chikungunya (CHIKV) virus can circulate as co-infection.
Gaurav Badoni +6 more
doaj +1 more source
Cognitive Dysfunction of Chikungunya Virus Infection in Older Adults
Frontiers in Psychiatry, 2022 Background Chikungunya fever is a disabling articular disease caused by chikungunya virus (CHIKV). In the past decade it has affected millions of people across America, Africa, Asia, and Europe, turning this infection into a public health concern.
V. G. M. N. P. Peixoto +3 more
semanticscholar +1 more source
Antagonism of the Sodium-Potassium ATPase Impairs Chikungunya Virus Infection
mBio, 2016 Chikungunya virus (CHIKV) is a reemerging alphavirus that has caused epidemics of fever, arthralgia, and rash worldwide. There are currently no licensed vaccines or antiviral therapies available for the prevention or treatment of CHIKV disease.
Alison W. Ashbrook +7 more
doaj +1 more source
DNA Damage Response Signaling Is Crucial for Effective Chikungunya Virus Replication
bioRxiv, 2022 Being intracellular parasites, viruses require several host cell machineries for effectively replicating their genome, along with virus-encoded enzymes. One of the strategies involves hijacking of the DDR pathways.
Sanchari Chatterjee +14 more
semanticscholar +1 more source
Effectiveness of CHIKV vaccine VLA1553 demonstrated by passive transfer of human sera
JCI Insight, 2022 Chikungunya virus (CHIKV) is a reemerging mosquito-borne alphavirus responsible for numerous outbreaks. Chikungunya can cause debilitating acute and chronic disease.
Pierre Roques +12 more
doaj +1 more source
Effect of Cationic Lipid Nanoparticle Loaded siRNA with Stearylamine against Chikungunya Virus
Molecules, 2022 Chikungunya is an infectious disease caused by mosquito-transmitted chikungunya virus (CHIKV). It was reported that NS1 and E2 siRNAs administration demonstrated CHIKV inhibition in in vitro as well as in vivo systems.
Manish Kumar Jeengar +5 more
semanticscholar +1 more source
Development of Neutralization Assay Using an eGFP Chikungunya Virus
Viruses, 2016 Chikungunya virus (CHIKV), a member of the Alphavirus genus, is an important human emerging/re-emerging pathogen. Currently, there are no effective antiviral drugs or vaccines against CHIKV infection. Herein, we construct an infectious clone of CHIKV and
Cheng-Lin Deng +11 more
doaj +1 more source
Chikungunya Immunopathology as It Presents in Different Organ Systems
Viruses, 2022 Chikungunya virus (CHIKV) is currently an urgent public health problem as high morbidity from the virus leaves populations with negative physical, social, and economic impacts.
Elizabeth M. Traverse +5 more
doaj +1 more source