Results 31 to 40 of about 14,798 (236)
Construction and Evaluation of Recombinant Adenovirus Candidate Vaccines for Chikungunya Virus
Viruses, 2022 Chikungunya virus (CHIKV) is a mosquito-borne virus. The emergence of CHIKV infection has raised global concern, and there is a growing need to develop safe and effective vaccines.
Liang Cao +10 more
doaj +1 more source
Peptide aptamer-based time-resolved fluoroimmunoassay for CHIKV diagnosis
Virology Journal, 2023 Abstract Background Chikungunya virus (CHIKV) and Dengue virus (DENV) have similar clinical symptoms, which often induce misdiagnoses. Therefore, an antigen detection diagnostic system that can clearly identify these two viruses is desirable.
Tonggong Liu +8 more
openaire +3 more sources
A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs [PDF]
, 2016 Chikungunya virus (CHIKV) is a globally spreading alphavirus against which there is no commercially available vaccine or therapy. Here we use a genome-wide siRNA screen to identify 156 proviral and 41 antiviral host factors affecting CHIKV replication ...
Berre, Stefano +16 more
core +5 more sources
Development and Application of Treatment for Chikungunya Fever
Research and Reports in Tropical Medicine, 2022 Erin M Millsapps, Emma C Underwood, Kelli L Barr Center for Global Health and Infectious Disease Research, University of South Florida, Tampa, FL, USACorrespondence: Kelli L Barr, Center for Global Health and Infectious Disease Research, University of ...
Millsapps EM, Underwood EC, Barr KL
doaj
Sri Lankan Journal of Infectious Diseases, 2023 Background: Chikungunya (CHIKV), Zika (ZV) and dengue (DENV) viruses are transmitted by Aedes mosquitoes. CHIKV, ZV and DENV infections produce similar clinical features during the early phase of the illness.
S. Briyangari +3 more
doaj +1 more source
The interferon-stimulated gene IFITM3 restricts infection and pathogenesis of arthritogenic and encephalitic alphaviruses [PDF]
, 2016 Host cells respond to viral infections by producing type I interferon (IFN), which induces the expression of hundreds of interferon-stimulated genes (ISGs).
Diamond, Michael S +4 more
core +2 more sources
Development of Neutralization Assay Using an eGFP Chikungunya Virus
Viruses, 2016 Chikungunya virus (CHIKV), a member of the Alphavirus genus, is an important human emerging/re-emerging pathogen. Currently, there are no effective antiviral drugs or vaccines against CHIKV infection. Herein, we construct an infectious clone of CHIKV and
Cheng-Lin Deng +11 more
doaj +1 more source
Understanding the Wolbachia-mediated inhibition of arboviruses in mosquitoes: progress and challenges [PDF]
, 2014 Arthropod-borne viruses (arboviruses) pose a considerable threat to human and animal health, yet effective control measures have proven difficult to implement, and novel means of controlling their replication in arthropod vectors, such as mosquitoes, are
Dietrich, Isabelle +3 more
core +1 more source
Preparation and application of chikungunya pseudovirus containing double reporter genes
Scientific Reports, 2022 Chikungunya virus (CHIKV), a highly infectious and rapidly spread viral pathogen, is classified as a pathogenic agent at the biosafety level 3. Operation of live authentic CHIKV needs a specific laboratory with the P3 or above containment, which greatly ...
Chunyan Su +7 more
doaj +1 more source
ACS Omega, 2019 Antiviral therapy is crucial for the circumvention of viral epidemics. The unavailability of a specific antiviral drug against the chikungunya virus (CHIKV) disease has created an alarming situation to identify or develop potent chemical molecules for ...
Ninad Puranik +5 more
semanticscholar +1 more source