Results 81 to 90 of about 1,034,528 (314)

Child and Adolescent Mental Health Around The World: Challenges for Progress [PDF]

, 2005
Child and adolescent mental health is an essential component of overall health and its importance is gaining increased recognition. Current events have heightened an interest in the mental health of youth. Unfortunately, too often this is due to concerns
Belfer, Myron L
core  

Behavioural outcomes and psychopathology during adolescence [PDF]

, 2013
Preterm birth is associated with a high risk of residual neurodevelopmental disability and cognitive impairment. These problems are closely associated with psychiatric disorders and thus it is unsurprising that preterm birth also confers high risk for ...
Johnson, Samantha J., Wolke, Dieter
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Child Psychiatric Disorders Presenting to a Tertiary Multidisciplinary Child Development Service in Bangladesh

Bangladesh Journal of Child Health, 2012
Background: Shishu Bikash Kendra (SBK or Child Development Center) of the Dhaka Shishu (Children’s) Hospital (DSH) has been using a multidisciplinary approach for assessment and management of children with various neurodevelopmental disorders since its establishment in 1991.
Naila Zaman Khan, Mustafa Mahbub, Mahmuda Khatun, Humaira Muslima, Dilara Begum, Rezina Parvin, Monowara Parveen, Farzana Islam   +7 more
openaire   +2 more sources

Системне дослідження особливостей засвоєння складоритму дітьми з порушеннями мовлення [PDF]

, 2017
We consider mastering the composition and the rhythm in terms of sensory development of the child with speech disorders. Perception of composition and rhythm, its imitation, memorization, reproduction are provided by various sensory systems and psychical
Бабич, Наталія Миколаїівна, Луцько, Катерина Василівна, Таран, Оксана Петрівна   +2 more
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Language outcomes and influencing factors in children with language delay: a retrospective cohort analysis

Scientific Reports
Language delay (LD) is a common developmental issue, but the understanding of its natural language outcomes is still limited. This study tracked the language development outcomes and influencing factors of LD longitudinally, providing a basis for early ...
Lin Zhu, Yuan Ding, Jing Tan, Siqi Chen, Juan Tan, Qiujing Wei, Ying Dai, Bin Peng, Xiao Liu, Li Chen   +9 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Psy-expertise, therapeutic culture and the politics of the personal in development [PDF]

, 2017
Expertise stemming from the psy disciplines is increasingly and explicitly shaping international development policy and practice. Whilst some policy makers see the use of psy expertise as a new way to reduce poverty, increase economic efficiency, and ...
Klein, E., Mills, C.
core   +2 more sources