Results 11 to 20 of about 210,137 (310)

Skeletal adverse events in childhood cancer survivors : An Adult Life after Childhood Cancer in Scandinavia cohort study [PDF]

open access: yes, 2021
The dynamic growth of the skeleton during childhood and adolescence renders it vulnerable to adverse effects of cancer treatment. The lifetime risk and patterns of skeletal morbidity have not been described in a population-based cohort of childhood ...
Niinimäki, R. (Riitta)   +56 more
core   +1 more source

Phase II-like murine trial identifies synergy between dexamethasone and dasatinib in T-cell acute lymphoblastic leukemia

open access: yesHaematologica, 2020
T-cell Acute Lymphoblastic Leukemia (T-ALL) is frequently characterized by glucocorticoid (GC) resistance, which is associated with inferior outcomes, thus highlighting the need for novel therapeutic approaches for GC resistant T-ALL.
Yuzhe Shi   +10 more
doaj   +1 more source

scATAC-pro: a comprehensive workbench for single-cell chromatin accessibility sequencing data

open access: yesGenome Biology, 2020
Single-cell chromatin accessibility sequencing has become a powerful technology for understanding epigenetic heterogeneity of complex tissues. However, there is a lack of open-source software for comprehensive processing, analysis, and visualization of ...
Wenbao Yu   +4 more
doaj   +1 more source

Vitamin K and childhood cancer: a report from the United Kingdom Childhood Cancer Study [PDF]

open access: yes, 2003
The relationship between neonatal vitamin K received by the intramuscular (i.m.) route and the development of leukaemia or other cancers was investigated as part of a national case–control study of childhood cancer, using data abstracted from obstetric ...
Eden, O.B.   +24 more
core   +1 more source

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

open access: yesHaematologica, 2018
Intrachromosomal amplification of chromosome 21 is a heterogeneous chromosomal rearrangement occurring in 2% of cases of childhood precursor B-cell acute lymphoblastic leukemia.
Paul. B. Sinclair   +18 more
doaj   +1 more source

Childhood leukaemia: long-term excess mortality and the proportion 'cured'. [PDF]

open access: yes, 2008
Survival from childhood leukaemia has increased, but the proportion of children cured is unknown. The proportion 'cured' is defined as the proportion of survivors for whom, as a group, there is no longer excess mortality compared to the general ...
Shah, A.   +17 more
core   +1 more source

Equivalent doses for anticancer agents used in pediatric oncology: A literature review and evaluation of a novel approach for conversion factors

open access: yesCancer Reports, 2023
Background Epidemiological research on late effects of therapy shows the necessity to aggregate chemotherapy agents to substance classes. This requires using conversion factors by substance classes.
Meike Ressing   +11 more
doaj   +1 more source

Cancer of the nasopharynx in childhood [PDF]

open access: yesCancer, 1990
Between 1964 and 1983, 54,304 cases of nasopharyngeal carcinoma (NPC) patients were diagnosed at the Tumor Hospital, Sun Yat-Sen University of Medical Sciences, Guangzhou, People's Republic of China. Of the total, 53 (0.1%) cases were younger than 14 years of age, and of these, none were Stage I, four (8%) were Stage II, 36 (68%) were Stage III, and 12
openaire   +2 more sources

Ionizing and non-ionizing radiation and the risk of childhood cancer-illustrated with domestic radon and radio frequency electromagnetic field exposure [PDF]

open access: yes, 2013
Background Children are exposed to many different environmental factors, including exposure to low-dose ionizing radiation and to non-ionizing radiation.
Hauri, Dimitri
core   +1 more source

Income disparities between adult childhood cancer survivors and their peers—A register‐based cohort study from the SALiCCS research programme

open access: yesCancer Medicine, 2023
Background Childhood cancer survivors face various adverse consequences. This Nordic register‐based cohort study aimed to assess whether survivors of childhood cancer are more likely to have low income than their peers.
Anniina Kyrönlahti   +15 more
doaj   +1 more source

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