Results 21 to 30 of about 187,093 (264)

Alex's Lemonade Stand Foundation squeezes in hope for childhood cancer: an interview with Liz and Jay Scott [PDF]

Disease Models & Mechanisms
Liz Scott, Jay Scott, Alex's Lemonade Stand Foundation   +2 more
doaj   +2 more sources

scATAC-pro: a comprehensive workbench for single-cell chromatin accessibility sequencing data

Genome Biology, 2020
Single-cell chromatin accessibility sequencing has become a powerful technology for understanding epigenetic heterogeneity of complex tissues. However, there is a lack of open-source software for comprehensive processing, analysis, and visualization of ...
Wenbao Yu, Yasin Uzun, Qin Zhu, Changya Chen, Kai Tan   +4 more
doaj   +1 more source

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Haematologica, 2018
Intrachromosomal amplification of chromosome 21 is a heterogeneous chromosomal rearrangement occurring in 2% of cases of childhood precursor B-cell acute lymphoblastic leukemia.
Paul. B. Sinclair, Helen H. Blair, Sarra L. Ryan, Lars Buechler, Joanna Cheng, Jake Clayton, Rebecca Hanna, Shaun Hollern, Zoe Hawking, Matthew Bashton, Claire J. Schwab, Lisa Jones, Lisa J. Russell, Helen Marr, Peter Carey, Christina Halsey, Olaf Heidenreich, Anthony V. Moorman, Christine J. Harrison   +18 more
doaj   +1 more source

Equivalent doses for anticancer agents used in pediatric oncology: A literature review and evaluation of a novel approach for conversion factors

Cancer Reports, 2023
Background Epidemiological research on late effects of therapy shows the necessity to aggregate chemotherapy agents to substance classes. This requires using conversion factors by substance classes.
Meike Ressing, Cornelia Becker, Christian Müller, Seyed Hamidreza Mahmoudpour, Gabriele Calaminus, Thorsten Langer, Friederike Erdmann, Mathias Voigt, Melanie Kaiser, Peter Kaatsch, Maria Blettner, Claudia Spix   +11 more
doaj   +1 more source

Cancer of the nasopharynx in childhood [PDF]

Cancer, 1990
Between 1964 and 1983, 54,304 cases of nasopharyngeal carcinoma (NPC) patients were diagnosed at the Tumor Hospital, Sun Yat-Sen University of Medical Sciences, Guangzhou, People's Republic of China. Of the total, 53 (0.1%) cases were younger than 14 years of age, and of these, none were Stage I, four (8%) were Stage II, 36 (68%) were Stage III, and 12
openaire   +2 more sources

Income disparities between adult childhood cancer survivors and their peers—A register‐based cohort study from the SALiCCS research programme

Cancer Medicine, 2023
Background Childhood cancer survivors face various adverse consequences. This Nordic register‐based cohort study aimed to assess whether survivors of childhood cancer are more likely to have low income than their peers.
Anniina Kyrönlahti, Friederike Erdmann, Maria Feychting, Line Elmerdahl Frederiksen, Elli Hirvonen, Liisa Maria Korhonen, Anja Krøyer, Luzius Mader, Nea Malila, Hanna Mogensen, Camilla Pedersen, Mats Talbäck, Mervi Taskinen, Jeanette Falck Winther, Laura Madanat‐Harjuoja, Janne Pitkäniemi   +15 more
doaj   +1 more source

Stress-Induced Isoforms of MDM2 and MDM4 Correlate with High-Grade Disease and an Altered Splicing Network in Pediatric Rhabdomyosarcoma

Neoplasia: An International Journal for Oncology Research, 2013
Pediatric rhabdomyosarcoma (RMS) is a morphologically and genetically heterogeneous malignancy commonly classified into three histologic subtypes, namely, alveolar, embryonal, and anaplastic.
Aishwarya G. Jacob, Dennis O'Brien, Ravi K. Singh, Daniel F. Comiskey, Jr, Robert M. Littleton, Fuad Mohammad, Jordan T. Gladman, Maria C. Widmann, Selvi C. Jeyaraj, Cheryl Bolinger, James R. Anderson, Donald A. Barkauskas, Kathleen Boris-Lawrie, Dawn S. Chandler   +13 more
doaj   +1 more source

Circulating tumor DNA reveals mechanisms of lorlatinib resistance in patients with relapsed/refractory ALK-driven neuroblastoma

Nature Communications, 2023
Activating point mutations in Anaplastic Lymphoma Kinase (ALK) have positioned ALK as the only mutated oncogene tractable for targeted therapy in neuroblastoma.
Esther R. Berko, Gabriela M. Witek, Smita Matkar, Zaritza O. Petrova, Megan A. Wu, Courtney M. Smith, Alex Daniels, Joshua Kalna, Annie Kennedy, Ivan Gostuski, Colleen Casey, Kateryna Krytska, Mark Gerelus, Dean Pavlick, Susan Ghazarian, Julie R. Park, Araz Marachelian, John M. Maris, Kelly C. Goldsmith, Ravi Radhakrishnan, Mark A. Lemmon, Yaël P. Mossé   +21 more
doaj   +1 more source

Patients’, parents’, and survivors’ perspective about AI applications in pediatric oncology

EJC Paediatric Oncology
Patients, parents and survivors of childhood cancer are those who represent the critical link between the clinical and technical research spheres.
Hyseni Bocolli Albina, Schneider Carina, Bastos Pais Teresa, Willi Michaela, Brunmair Mattias   +4 more
doaj   +1 more source

HOW ARE YOU FEELING TODAY? – Gaps and opportunities in capturing patient reported outcomes (PROs) in Pediatric Cancer Care

EJC Paediatric Oncology
Including children's perspectives in healthcare and clinical trials, particularly in pediatric oncology, is critical to promoting child-centered care. Research has shown that even very young children can understand complex medical concepts, highlighting ...
Anna Zettl, Hannah Gsell, Karolina Maślak, Antti Karjalainen, Ulrike Leiss, Anita Kienesberger, Carina Schneider   +6 more
doaj   +1 more source