Results 41 to 50 of about 4,157,414 (204)

Deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray

STAR Protocols, 2023
Summary: Here, we present a protocol for deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray.
James P.R. Hacking, Dean Thompson, Edward C. Schwalbe, Steven C. Clifford, Daniel Williamson   +4 more
doaj   +1 more source

Depression and cancer: physiological and psychological markers [PDF]

, 2010
PhDAim: To investigate potential markers for depression and poor quality of life (QoL) in head and neck (HN) and colorectal (CR) cancer patients. Background: Comorbid depression is strongly related to decreased QoL in cancer patients and may increase ...
Archer, Josephine Astrid
core   +3 more sources

Human macrophages engineered to secrete a bispecific T cell engager support antigen-dependent T cell responses to glioblastoma

Journal for ImmunoTherapy of Cancer, 2020
Background Targeted and effective treatment options are needed for solid tumors, including glioblastoma (GBM), where survival rates with standard treatments are typically less than 2 years from diagnosis.
Shannon A Kreuser, Harrison Chinn, Kole R DeGolier, Lisa R Matsumoto, Richard G Ellenbogen, Courtney A Crane, Jennifer L Gardell, Brooke Prieskorn, Stephanie Balcaitis, Amira Davis   +9 more
doaj   +1 more source

Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

BMC Biology, 2023
Background Tumors are complex tissues containing collections of phenotypically diverse malignant and nonmalignant cells. We know little of the mechanisms that govern heterogeneity of tumor cells nor of the role heterogeneity plays in overcoming stresses,
Sanjana Rajan, Emily M. Franz, Camille A. McAloney, Tatyana A. Vetter, Maren Cam, Amy C. Gross, Cenny Taslim, Meng Wang, Matthew V. Cannon, Alexander Oles, Ryan D. Roberts   +10 more
doaj   +1 more source

Second primary cancers in people who had cancer as children: an Australian Childhood Cancer Registry population-based study [PDF]

, 2019
Objective: To investigate the incidence of second primary cancers in people diagnosed with cancer during childhood. Design, setting: Retrospective, population-based study; analysis of Australian Childhood Cancer Registry data.
Baade, Peter D., Baade, Peter D, Moore, Andrew S., Aitken, Joanne F., Moore, Andrew S, Youlden, Danny R., Valery, Patricia C., Valery, Patricia C, Youlden, Danny R, Green, Adèle C., Aitken, Joanne F, Green, Adèle C, Valery, PC, Youlden, DR, Aitken, JF, Baade, PD, Moore, AS   +16 more
core   +1 more source

CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma

Nature Communications
Novel chimeric antigen receptor (CAR) T-cell approaches are needed to improve therapeutic efficacy in solid tumors. High-risk neuroblastoma is an aggressive pediatric solid tumor that expresses cell-surface GPC2 and GD2 with a tumor microenvironment ...
Guillem Pascual-Pasto, Brendan McIntyre, Margaret G. Hines, Anna M. Giudice, Laura Garcia-Gerique, Jennifer Hoffmann, Pamela Mishra, Stephanie Matlaga, Simona Lombardi, Rawan Shraim, Patrick M. Schürch, Mark Yarmarkovich, Ted J. Hofmann, Fatemeh Alikarami, Daniel Martinez, Matthew Tsang, Luis Gil-de-Gómez, Timothy T. Spear, Kathrin M. Bernt, Adam J. Wolpaw, Dimiter S. Dimitrov, Wei Li, Kristopher R. Bosse   +22 more
doaj   +1 more source

Translating and culturally adapting the shortened version of the Hospital Ethical Climate Survey (HECS-S) – retaining or modifying validated instruments

BMC Medical Ethics, 2018
Background The Hospital Ethical Climate Survey (HECS) was developed in the USA and later shortened (HECS-S). HECS has previously been translated into Swedish and the aim of this study was to describe a process of translating and culturally adapting HECS ...
Pernilla Pergert, Cecilia Bartholdson, Marika Wenemark, Kim Lützén, Margareta af Sandeberg   +4 more
doaj   +1 more source

Lung Cancer as a Subsequent Malignant Neoplasm in Survivors of Childhood Cancer

, 2021
BACKGROUND: Lung cancer, the most common cancer cause of death in adults, has not been well studied as a subsequent malignant neoplasm (SMN) in childhood cancer survivors.
Smith, Susan A., Dietz, Andrew C., Yuan, Yan, Turcotte, Lucie M, Chen, Yan, Mulrooney, Daniel A., Dietz, Andrew C, Yasui, Yutaka, Turcotte, Lucie M., Armstrong, Gregory T, Howell, Rebecca M, Ghosh, Taumoha, Mulrooney, Daniel A, Smith, Susan A, Neglia, Joseph P., Neglia, Joseph P, Armstrong, Gregory T., Gregory T. Armstrong, Joseph P. Neglia, Rebecca M. Howell, Andrew C. Dietz, Susan A. Smith, Daniel A. Mulrooney, Yan Chen, Taumoha Ghosh, Lucie M. Turcotte, Yan Yuan, Yutaka Yasui   +27 more
core   +1 more source

The mainz resilience assessment in childhood cancer (MRAcc): development of a novel age-specific patient-reported outcome measure to assess resilience in childhood cancer patients

BMC Cancer
Background During intensive cancer treatment, children, adolescents and young adults are exposed to numerous toxicities and psychosocial stressors that can cause psychosocial distress and impair mental health.
Marie A. Neu, Franziska Ortmüller, Abigale L. Robinson, Elias Dreismickenbecker, Henrike Otto, Lena Wypyrsczyk, Mareike Kühn, Michèle Wessa, Oliver Tüscher, Joerg Faber, on behalf of the FORTEe Consortium   +10 more
doaj   +1 more source

Selection of dormant cells during treatment of T-lineage lymphoblastic leukemia and CREB as a therapeutic target

Haematologica
Not available.
Dino Masic, Hayden Bell, Frederik W van Delft, Julie Anne Elizabeth Irving   +3 more
doaj   +1 more source