Results 61 to 70 of about 210,137 (310)

Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

BMC Biology, 2023
Background Tumors are complex tissues containing collections of phenotypically diverse malignant and nonmalignant cells. We know little of the mechanisms that govern heterogeneity of tumor cells nor of the role heterogeneity plays in overcoming stresses,
Sanjana Rajan, Emily M. Franz, Camille A. McAloney, Tatyana A. Vetter, Maren Cam, Amy C. Gross, Cenny Taslim, Meng Wang, Matthew V. Cannon, Alexander Oles, Ryan D. Roberts   +10 more
doaj   +1 more source

Radon and childhood cancer [PDF]

British Journal of Cancer, 2002
British Journal of Cancer (2002) 87, 1336–1337.
openaire   +2 more sources

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma

Nature Communications
Novel chimeric antigen receptor (CAR) T-cell approaches are needed to improve therapeutic efficacy in solid tumors. High-risk neuroblastoma is an aggressive pediatric solid tumor that expresses cell-surface GPC2 and GD2 with a tumor microenvironment ...
Guillem Pascual-Pasto, Brendan McIntyre, Margaret G. Hines, Anna M. Giudice, Laura Garcia-Gerique, Jennifer Hoffmann, Pamela Mishra, Stephanie Matlaga, Simona Lombardi, Rawan Shraim, Patrick M. Schürch, Mark Yarmarkovich, Ted J. Hofmann, Fatemeh Alikarami, Daniel Martinez, Matthew Tsang, Luis Gil-de-Gómez, Timothy T. Spear, Kathrin M. Bernt, Adam J. Wolpaw, Dimiter S. Dimitrov, Wei Li, Kristopher R. Bosse   +22 more
doaj   +1 more source

Translating and culturally adapting the shortened version of the Hospital Ethical Climate Survey (HECS-S) – retaining or modifying validated instruments

BMC Medical Ethics, 2018
Background The Hospital Ethical Climate Survey (HECS) was developed in the USA and later shortened (HECS-S). HECS has previously been translated into Swedish and the aim of this study was to describe a process of translating and culturally adapting HECS ...
Pernilla Pergert, Cecilia Bartholdson, Marika Wenemark, Kim Lützén, Margareta af Sandeberg   +4 more
doaj   +1 more source

Adverse socioeconomic conditions in childhood and cause specific adult mortality: prospective observational study [PDF]

, 1998
<b>Objective:</b> To investigate the association between social circumstances in childhood and mortality from various causes of death in adulthood. Design: Prospective observational study. Setting: 27 workplaces in the west of Scotland.
Blane, D., C. Hart, D. Blane, Davey Smith, G., Hole, D., Hart, C.L., G. D. Smith, D. Hole   +7 more
core   +1 more source

Common maternal infections during pregnancy and childhood leukaemia in the offspring: findings from six international birth cohorts

, 2021
Background Previous epidemiological studies have found positive associations between maternal infections and childhood leukaemia; however, evidence from prospective cohort studies is scarce.
F Olsen, Sjurdur, Rahimi, Kazem, Haberg, Siri, Wiemels, Joseph, Ward, Mary H, Olsen, Jørn, Ponsonby, Anne-Louise, Lemeshow, Stanley, He, Jian-rong, Olsen, Jorn, Murphy, Michael, Ward, Mary, Dwyer, Terence, Qiu, Xiu, Hirst, Jane E, Phillips, Gary S, Golding, Jean, Wiemels, Joseph L, Magnus, Per, Linet, Martha S, Tikellis, Gabriella, Murphy, Michael FG, Murphy, Michael F G, Paltiel, Ora, Linet, Martha, Håberg, Siri E, Hirst, Jane, Ramakrishnan, Rema, Klebanoff, Mark, Olsen, Sjurdur   +29 more
core   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Selection of dormant cells during treatment of T-lineage lymphoblastic leukemia and CREB as a therapeutic target

Haematologica
Not available.
Dino Masic, Hayden Bell, Frederik W van Delft, Julie Anne Elizabeth Irving   +3 more
doaj   +1 more source

Height and risk of death among men and women: aetiological implications of associations with cardiorespiratory disease and cancer mortality [PDF]

, 2000
OBJECTIVES: Height is inversely associated with cardiovascular disease mortality risk and has shown variable associations with cancer incidence and mortality.
Upton, M., Davey Smith, G., Watt, G., Hart, C.L., Gillis, C.R., Hawthorne, V.M.   +5 more
core   +1 more source