Results 61 to 70 of about 4,157,414 (204)

Ethics support personnel’s perceptions of patient and parent participation in clinical ethics support services in pediatric oncology

open access: yesBMC Medical Ethics
Background There is an ongoing discourse about patient and parent participation (PPP) in Clinical Ethics Support Services (CESS), and this paper focuses specifically on case-based CESS.
Isabelle Billstein   +4 more
doaj   +1 more source

Direct oHSV Infection Induces DC Maturation and a Tumor Therapeutic Response

open access: yesViruses
Oncolytic herpes simplex virus (oHSV) is a promising cancer immunotherapy that induces tumor cell lysis and stimulates anti-tumor immunity. Our previous single-cell RNA sequencing analysis of oHSV-treated medulloblastoma tumors revealed expansion and ...
Doyeon Kim   +8 more
doaj   +1 more source

Differentiation of Human Embryonic Stem Cells to Sympathetic Neurons: A Potential Model for Understanding Neuroblastoma Pathogenesis

open access: yesStem Cells International, 2018
Background and Aims. Previous studies modelling human neural crest differentiation from stem cells have resulted in a low yield of sympathetic neurons.
Jane Carr-Wilkinson   +10 more
doaj   +1 more source

Childhood Cancer Survivorship: A Qualitative Description of Parental Experiences with Survivorship Care Plans [PDF]

open access: yes, 2015
Advancements to treatment and supportive care strategies for childhood cancer have resulted in a shift to managing late effects in the latter stages of the cancer trajectory.
Adams, Trina
core  

The global burden of childhood and adolescent cancer in 2017: an analysis of the Global Burden of Disease Study 2017 [PDF]

open access: yes, 2019
: Background Accurate childhood cancer burden data are crucial for resource planning and health policy prioritisation. Model-based estimates are necessary because cancer surveillance data are scarce or non-existent in many countries.
Reiner, Robert C.   +373 more
core   +1 more source

Genetics of childhood cancer [PDF]

open access: yesBritish Medical Bulletin, 1996
In the last 5 years, there has been a tremendous increase in understanding of the molecular genetics of several childhood cancers. The genes for more than 10 cancer predisposition syndromes are now cloned and the molecular basis of their functioning is being analysed.
openaire   +2 more sources

Cooperation of Oncolytic Herpes Virotherapy and PD-1 Blockade in Murine Rhabdomyosarcoma Models

open access: yesScientific Reports, 2017
Oncolytic virotherapy is an effective immunotherapeutic approach for cancer treatment via a multistep process including direct tumor cell lysis, induction of cytotoxic or apoptosis-sensitizing cytokines and promotion of antitumor T cell responses.
Chun-Yu Chen   +9 more
doaj   +1 more source

The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia

open access: yesBlood Cancer Journal
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy that expresses high levels of the enzyme aldo-keto reductase family 1 member C3 (AKR1C3).
Cara E. Toscan   +23 more
doaj   +1 more source

Childhood cancer

open access: yes, 2018
Posters produced by students to promote childhood cancer for Radiation Therapy coursePoster 3_Childhood cancer: Cancer in childhood is increasing each year, this informative poster shows what the warning signs and symptoms ...
Martin, C. and Hudson, L. (Supervisors)
core  

Global burden of cancer in children and adolescents aged 0-19 years, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

open access: yes
Claudia E Kuehni is a collaborator of GBD 2023 Childhood Cancer Collaborators.Background Information on childhood cancer burden is crucial for effective cancer policy planning.
GBD 2023 Childhood Cancer Collaborators
core   +1 more source

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