Results 51 to 60 of about 4,157,414 (204)

Early childhood flexibility practices and patterns: report 2014 [PDF]

open access: yes, 2014
The Early childhood flexibility practices and patterns report highlights recommendations and future directions for early childhood education and care (ECEC) services in providing flexible arrangements for families and local communities.
Early Childhood Australia
core  

Cancer Trends: Childhood cancer

open access: yes, 2017
This is the second trends report NCRI has published on childhood cancers, updating a previous report covering 1994-20111. To facilitate summary of the amount and complexity of material included, presentation and layout has been in general retained from ...
National Cancer Registry Ireland (NCRI)
core  

Radon and childhood cancer [PDF]

open access: yesBritish Journal of Cancer, 2002
British Journal of Cancer (2002) 87, 1336–1337.
openaire   +2 more sources

TRIB3 silencing promotes the downregulation of Akt pathway and PAX3-FOXO1 in high-risk rhabdomyosarcoma

open access: yesExperimental Hematology & Oncology
Rhabdomyosarcoma (RMS), such as other childhood tumors, has witnessed treatment advancements in recent years. However, high-risk patients continue to face poor survival rates, often attributed to the presence of the PAX3/7-FOXO1 fusion proteins, which ...
Gabriel Gallo-Oller   +14 more
doaj   +1 more source

A Multimethod, Patient-Oriented Examination of Pain in Childhood Cancer Survivors

open access: yes, 2021
Emerging theory and empirical work suggest that pain is a significant late effect of childhood cancer and trigger of fear of cancer recurrence (FCR). This dissertation aimed to: explore the experience and meaning of pain after childhood cancer (Study 1);
Tutelman, Perri
core  

Oncolytic HSV-IL27 expression improves CD8 T cell function and therapeutic activity in syngeneic glioma models

open access: yesJournal for ImmunoTherapy of Cancer
Background Malignant gliomas (MGs) are the most common primary brain malignancies and are considered universally fatal. Oncolytic herpes simplex viruses (oHSVs) are promising immunotherapeutics capable of selectively lysing cancer cells, eliciting ...
Alexia K Martin   +7 more
doaj   +1 more source

Single-cell mass cytometry and machine learning predict relapse in childhood leukemia

open access: yesMolecular & Cellular Oncology, 2018
Improved insight into cancer cell populations responsible for treatment failure will lead to better outcomes for patients. We herein highlight a single-cell study of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) at diagnosis that revealed ...
Jolanda Sarno, Kara L. Davis
doaj   +1 more source

"Obubomi Bulukhuni/It is a Hard Life, This": Journeys in and narratives of childhood cancer in a South African public healthcare context [PDF]

open access: yes, 2011
This research examines the ways in which a history of social segregation together with present actions by the state interact to inform the nature of healthcare narratives of mothers and children in the case of a childhood cancer diagnosis.
Riekert, Yolande
core   +1 more source

A humanized anaplastic lymphoma kinase (ALK)-directed antibody-drug conjugate with pyrrolobenzodiazepine payload demonstrates efficacy in ALK-expressing cancers

open access: yesNature Communications
The Anaplastic Lymphoma Kinase (ALK) gene is a receptor tyrosine kinase (RTK) with expression restricted to the developing nervous system. Most neuroblastomas express native ALK protein on the cell surface and ALK is uniformly overexpressed in fusion ...
Alberto D. Guerra   +32 more
doaj   +1 more source

Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma

open access: yesNature Communications
Diffuse intrinsic pontine glioma (DIPG) is a fatal brainstem tumor desperately in need of better treatments. Chimeric antigen receptor (CAR) T cell therapies for DIPG have demonstrated clinical tolerability and bioactivity, but not universal benefit.
Edward Z. Song   +16 more
doaj   +1 more source

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