Results 31 to 40 of about 210,137 (310)

Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma

Scientific Reports, 2021
In cancer cells only, TLR3 acquires death receptor properties by efficiently triggering the extrinsic pathway of apoptosis with Caspase-8 as apical protease.
Marie-Anaïs Locquet, Gabriel Ichim, Joseph Bisaccia, Aurelie Dutour, Serge Lebecque, Marie Castets, Kathrin Weber   +6 more
doaj   +1 more source

Modeling Down Syndrome Myeloid Leukemia by Sequential Introduction of GATA1 and STAG2 Mutations in Induced Pluripotent Stem Cells with Trisomy 21

Cells, 2022
Children with Down syndrome (DS) have a high risk for acute myeloid leukemia (DS-ML). Genomic characterization of DS-ML blasts showed the presence of unique mutations in GATA1, an essential hematopoietic transcription factor, leading to the production of
Sonali P. Barwe, Aimy Sebastian, Ishnoor Sidhu, Edward Anders Kolb, Anilkumar Gopalakrishnapillai   +4 more
doaj   +1 more source

Cancer patterns among children of Turkish descent in Germany: a study at the German Childhood Cancer Registry

, 2008
Spallek J, Spix C, Zeeb H, Kaatsch P, Razum O. Cancer patterns among children of Turkish descent in Germany: a study at the German Childhood Cancer Registry. BMC Public Health.
Claudia Spix, Razum, Oliver, Kaatsch, Peter, Spallek Jacob, Spallek, Jacob, Zeeb Hajo, Spix, Claudia, Spix Claudia, Peter Kaatsch, Kaatsch Peter, Jacob Spallek, Hajo Zeeb, Razum Oliver, Oliver Razum, Zeeb, Hajo   +14 more
core   +1 more source

Important situations that capture moral distress in paediatric oncology

BMC Medical Ethics, 2020
Background The paediatric Moral Distress Scale-Revised (MDS-R) was previously translated and adapted to Swedish paediatric oncology. Cognitive interviews revealed five not captured situations among the 21 items, resulting in five added items: 22) Lack of
Margareta af Sandeberg, Cecilia Bartholdson, Pernilla Pergert   +2 more
doaj   +1 more source

Validation of questionnaire-reported chest wall abnormalities with a telephone interview in Swiss childhood cancer survivors

BMC Cancer, 2021
Background Chest wall abnormalities are a poorly studied complication after treatment for childhood cancer. Chest wall abnormalities are not well-described in the literature, and little is known on the impact on daily life of survivors.
Rahel Kasteler, Christa Lichtensteiger, Christina Schindera, Marc Ansari, Claudia E. Kuehni, for the Swiss Pediatric Oncology Group (SPOG) Scientific Committee   +5 more
doaj   +1 more source

The Challenge of Childhood Cancer

Ca-A Cancer Journal for Clinicians, 1968
exaly   +3 more sources

Suboptimal Vitamin D levels among adult survivors of childhood cancers

, 2016
Purpose: Vitamin D plays an important role in many bodily systems, with increasing evidence suggesting its importance for the prevention of chronic diseases and cancer.
Lisac, Robert; Department of Pediatric Oncology, Roswell Park Cancer Institute, Buffalo, New York, Mahoney, Martin C; Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, Rokitka, Denise A.; Department of Pediatric Oncology, Roswell Park Cancer Institute, Buffalo, New York, Heffler, Jennifer E; Department of Pediatric Oncology, Roswell Park Cancer Institute, Buffalo, New York, Zevon, Michael A; Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York   +4 more
core   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Cancer survival among children of Turkish descent in Germany 1980–2005: a registry-based analysis

, 2008
Spix C, Spallek J, Kaatsch P, Razum O, Zeeb H. Cancer survival among children of Turkish descent in Germany 1980–2005: a registry-based analysis. BMC Cancer.
Spix Claudia, Kaatsch Peter, Razum, Oliver, Kaatsch, Peter, Razum Oliver, Spallek Jacob, Spallek, Jacob, Zeeb Hajo, Spix, Claudia, Zeeb, Hajo   +9 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source