Results 31 to 40 of about 4,157,414 (204)

Validation of questionnaire-reported chest wall abnormalities with a telephone interview in Swiss childhood cancer survivors

BMC Cancer, 2021
Background Chest wall abnormalities are a poorly studied complication after treatment for childhood cancer. Chest wall abnormalities are not well-described in the literature, and little is known on the impact on daily life of survivors.
Rahel Kasteler, Christa Lichtensteiger, Christina Schindera, Marc Ansari, Claudia E. Kuehni, for the Swiss Pediatric Oncology Group (SPOG) Scientific Committee   +5 more
doaj   +1 more source

Meningiomas occurring during long-term survival after treatment for childhood cancer

, 2014
Childhood cancer is rare but improvements in treatment over the past five decades have resulted in a cohort of more than 30,000 long-term survivors of childhood cancer in the UK with more added annually.
Kennedy, C.R., Bhangoo, R., Pretorius, P., Sugden, E., Taylor, A.   +4 more
core   +1 more source

Risk stratification of childhood cancer survivors necessary for evidence-based clinical long-term follow-up [PDF]

, 2017
BACKGROUND: Reorganisation of clinical follow-up care in England was proposed by the National Cancer Survivorship Initiative (NCSI), based on cancer type and treatment, ranging from Level 1 (supported self-management) to Level 3 (consultant-led care ...
Oeffinger, Kevin C., Guha, J, Joyeeta Guha, Levitt, Gill A., Gill A Levitt, David L Winter, Emma R Lancashire, Kevin C Oeffinger, Raoul C Reulen, Guha, Joyeeta, Glaser, A, Glaser, Adam, Reulen, Raoul C; id_orcid, Clare Frobisher, Cutter, David J., Hawkins, MM, Adam Glaser, Lancashire, Emma R., Winter, DL, Kelly, Julie, Michael M Hawkins, Winter, David L., Hawkins, M, Reulen, RC, null null, Levitt, GA, Oeffinger, KC, Kelly, J, Frobisher, Clare; id_orcid, Cutter, DJ, David J Cutter, Frobisher, C, Lancashire, ER, Julie Kelly   +33 more
core   +1 more source

Hyperactive CREB subpopulations increase during therapy in pediatric B-lineage acute lymphoblastic leukemia

Haematologica, 2022
Persistence of residual disease in acute lymphoblastic leukemia (ALL) during the initial stages of chemotherapy is associated with inferior survival. To better understand clonal evolution and mechanisms of chemoresistance, we used multiparameter mass ...
Dino Masic, Kayleigh Fee, Hayden Bell, Marian Case, Gabby Witherington, Sophie Lansbury, Juan Ojeda-Garcia, David McDonald, Claire Schwab, Frederik W. van Delft, Andrew Filby, Julie Anne Elizabeth Irving   +11 more
doaj   +1 more source

Childhood Cancers: Hepatoblastoma

The Oncologist, 2000
Abstract Hepatoblastoma is the most common primary liver tumor in children, accounting for just over 1% of pediatric cancers. The etiology is unknown, but it has been associated with Beckwith-Weidemann syndrome, familial adenomatosis polypi, and low birth weight. The primary treatment is surgical resection, however, chemotherapy plays an
C E, Herzog, R J, Andrassy, F, Eftekhari
openaire   +2 more sources

Robust molecular subgrouping and reference-free aneuploidy detection in medulloblastoma using low-depth whole genome bisulfite sequencing

Acta Neuropathologica Communications
Medulloblastoma comprises four principal molecular disease groups and their component subgroups, each with distinct molecular and clinical features. Group assignment is currently achieved diagnostically using Illumina DNA methylation microarray.
Dean Thompson, Jemma Castle, Martin Sill, Stefan M. Pfister, Simon Bailey, Debbie Hicks, Steven C. Clifford, Edward C. Schwalbe   +7 more
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio
BMI‐1 (B‐cell‐specific Moloney murine leukemia virus integration site 1) has been implicated in both normal and cancer cell biology. While the canonical function of BMI‐1 involves epigenetic repression, novel extranuclear functions have been recently ...
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
doaj   +1 more source

Targeting the gp130/STAT3 Axis Attenuates Tumor Microenvironment Mediated Chemoresistance in Group 3 Medulloblastoma Cells

Cells, 2022
Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Of the four molecular subgroups, Group 3 MB is the most aggressive and has the worst prognosis.
Lakshana Sreenivasan, Ling Vicky Li, Pascal Leclair, Chinten James Lim   +3 more
doaj   +1 more source

Patient involvement in the development of childhood, adolescent and young adult cancer survivorship guidelines: recommendations from EU-CAYAS-NET ambassadors

Research Involvement and Engagement
Background Survivors of Childhood, Adolescent, and Young Adult (CAYA) cancer can face long-term health complications due to adverse effects of cancer and its treatment, necessitating lifelong follow-up care.
Jikke Wams, Jaap den Hartogh, Hannah Gsell, Carina Schneider, Barbara Brunmair, Anna Zettl, Zuzana Tomášiková, Anita Kienesberger, Katie Rizvi, Ana M. Totovina, Roderick Skinner, Jeroen te Dorsthorst, Helena J. H. van der Pal, Leontien C. M. Kremer, Elvira C. van Dalen, Renée L. Mulder, the EU-CAYAS-NET ambassadors and consortium   +16 more
doaj   +1 more source

Benefits of Exercise Training for Children and Adolescents Undergoing Cancer Treatment: Results From the Randomized Controlled MUCKI Trial

Frontiers in Pediatrics, 2020
Objective: In cancer patients, the impairment in muscle function is a frequently observed phenomenon. However, comprehensive evaluation of the effect of exercise training on muscle function in childhood cancer patients (CCPs) is sparse and therefore ...
Sandra Stössel, Marie A. Neu, Arthur Wingerter, Wilhelm Bloch, Philipp Zimmer, Claudia Paret, Khalifa El Malki, Freerk T. Baumann, Alexandra Russo, Nicole Henninger, Nadine Lehmann, Henrike Otto, Jörg Faber   +12 more
doaj   +1 more source