Results 51 to 60 of about 6,129,228 (249)

Global childhood cancer survival estimates and priority-setting: a simulation-based analysis.

The Lancet Oncology, 2019
BACKGROUND Accurate childhood cancer survival estimates are crucial for policy makers and clinicians for priority-setting and planning decisions. However, observed survival estimates are lacking for many countries, and when available, wide variation in ...
Zachary J. Ward, Jennifer M Yeh, Jennifer M Yeh, N. Bhakta, A. L. Frazier, F. Girardi, R. Atun   +6 more
semanticscholar   +1 more source

Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]

, 2018
Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco, Bonci, Enea, Celani, Camilla, Marrucci, Oriana, Pedetti, Valeria, Schiavetti, Amalia, Varrasso, Giulia   +6 more
core   +1 more source

Early Origins of Adult Cancer Risk Among Men and Women: Influence of Childhood Misfortune? [PDF]

, 2018
Objective—To examine the effect of five childhood misfortune domains—parental behavior, socioeconomic status, infectious diseases, chronic diseases, and impairments—on all-site and selected site-specific cancer prevalence and all-site cancer incidence ...
Ferraro, Kenneth F., Kemp, Blakelee R., Morton, Patricia M., Mustillo, Sarah A.   +3 more
core   +1 more source

Numb Isoforms Deregulation in Medulloblastoma and Role of p66 Isoform in Cancer and Neural Stem Cells [PDF]

, 2018
Numb is an intracellular protein with multiple functions. The two prevalent isoforms, Numb p66 and Numb p72, are regulators of differentiation and proliferation in neuronal development.
Agnese Po, Andrea Carai, Angela Mastronuzzi, Elisabetta Ferretti, Elisabetta Ferretti, Enrico De Smaele, Evelina Miele, Felice Giangaspero, Felice Giangaspero, Franco Locatelli, Franco Locatelli, Luana Abballe, Marta Moretti, Zein Mersini Besharat   +13 more
core   +9 more sources

Targeting the gp130/STAT3 Axis Attenuates Tumor Microenvironment Mediated Chemoresistance in Group 3 Medulloblastoma Cells

Cells, 2022
Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Of the four molecular subgroups, Group 3 MB is the most aggressive and has the worst prognosis.
Lakshana Sreenivasan, Ling Vicky Li, Pascal Leclair, Chinten James Lim   +3 more
doaj   +1 more source

Relationship Between Non-Hodgkin's Lymphoma and Blood Levels of Epstein-Barr Virus in Children in North-Western Tanzania: A Case Control Study. [PDF]

, 2013
Non-Hodgkin's Lymphomas (NHL) are common in African children, with endemic Burkitt's lymphoma (BL) being the most common subtype. While the role of Epstein-Barr Virus (EBV) in endemic BL is known, no data are available about clinical presentations of NHL
AH Filipovich, Anita De Rossi, AO Cavdar, Benson Kidenya, CE Klumb, D Kim, Damas Mwizamuholya, E Righetti, EK Mbidde, Erasmus Kamugisha, F Davi, G Nunnari, I Abbate, I Araujo, J Diebold, J Shapira, JES The, JL Young Jr, JT Sandlund, Kelsey, Maria Raffaella Petrara, MD Ogwang, MD Parkin, Ministry of Health and social welfare, MJ Boyle, MR Petrara, N Anwar, N Burighel, N Mutalima, National AIDS Control Programme, Nestory Masalu, P Aka, PA Chabay, Peter Rambau, R Hassan, R Newton, R Newton, RE Goldsby, Rogatus Kabyemera, S Lazzi, SB Murphy, SB Murphy, SC Peh, SJ Stevens, SM Mbulaiteye   +44 more
core   +3 more sources

Benefits of Exercise Training for Children and Adolescents Undergoing Cancer Treatment: Results From the Randomized Controlled MUCKI Trial

Frontiers in Pediatrics, 2020
Objective: In cancer patients, the impairment in muscle function is a frequently observed phenomenon. However, comprehensive evaluation of the effect of exercise training on muscle function in childhood cancer patients (CCPs) is sparse and therefore ...
Sandra Stössel, Marie A. Neu, Arthur Wingerter, Wilhelm Bloch, Philipp Zimmer, Claudia Paret, Khalifa El Malki, Freerk T. Baumann, Alexandra Russo, Nicole Henninger, Nadine Lehmann, Henrike Otto, Jörg Faber   +12 more
doaj   +1 more source

Passion with Purpose A Case Study of St. Jude Children’s Research Hospital [PDF]

, 2018
St. Jude Children’s Research Hospital is “leading the way the world understands, treats, and defeats childhood cancer and other life threatening diseases” (St. Jude Children’s Research Hospital). Fifty-five years ago when St.
Favuzza, Allyson
core   +1 more source

Robust molecular subgrouping and reference-free aneuploidy detection in medulloblastoma using low-depth whole genome bisulfite sequencing

Acta Neuropathologica Communications
Medulloblastoma comprises four principal molecular disease groups and their component subgroups, each with distinct molecular and clinical features. Group assignment is currently achieved diagnostically using Illumina DNA methylation microarray.
Dean Thompson, Jemma Castle, Martin Sill, Stefan M. Pfister, Simon Bailey, Debbie Hicks, Steven C. Clifford, Edward C. Schwalbe   +7 more
doaj   +1 more source

Deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray

STAR Protocols, 2023
Summary: Here, we present a protocol for deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray.
James P.R. Hacking, Dean Thompson, Edward C. Schwalbe, Steven C. Clifford, Daniel Williamson   +4 more
doaj   +1 more source