Results 71 to 80 of about 6,129,228 (249)

CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma

Nature Communications
Novel chimeric antigen receptor (CAR) T-cell approaches are needed to improve therapeutic efficacy in solid tumors. High-risk neuroblastoma is an aggressive pediatric solid tumor that expresses cell-surface GPC2 and GD2 with a tumor microenvironment ...
Guillem Pascual-Pasto, Brendan McIntyre, Margaret G. Hines, Anna M. Giudice, Laura Garcia-Gerique, Jennifer Hoffmann, Pamela Mishra, Stephanie Matlaga, Simona Lombardi, Rawan Shraim, Patrick M. Schürch, Mark Yarmarkovich, Ted J. Hofmann, Fatemeh Alikarami, Daniel Martinez, Matthew Tsang, Luis Gil-de-Gómez, Timothy T. Spear, Kathrin M. Bernt, Adam J. Wolpaw, Dimiter S. Dimitrov, Wei Li, Kristopher R. Bosse   +22 more
doaj   +1 more source

Does socioeconomic status account for racial and ethnic disparities in childhood cancer survival?

Cancer, 2018
For many childhood cancers, survival is lower among non‐Hispanic blacks and Hispanics in comparison with non‐Hispanic whites, and this may be attributed to underlying socioeconomic factors.
Rebecca D. Kehm, L. Spector, J. Poynter, D. Vock, S. Altekruse, T. Osypuk   +5 more
semanticscholar   +1 more source

Selection of dormant cells during treatment of T-lineage lymphoblastic leukemia and CREB as a therapeutic target

Haematologica
Not available.
Dino Masic, Hayden Bell, Frederik W van Delft, Julie Anne Elizabeth Irving   +3 more
doaj   +1 more source

Longitudinal development of cancer‐related fatigue and physical activity in childhood cancer patients

Pediatric Blood & Cancer, 2019
Cancer‐related fatigue is one of the most distressing side effects of childhood cancer treatment. Physical activity can decrease fatigue and has positive effects on other health outcomes. Most research on physical activity pertains to adults, and the few
E. M. van Dijk-Lokkart, Lindsay M. H. Steur, K. Braam, M. Veening, J. Huisman, T. Takken, M. Bierings, J. Merks, M. M. van den Heuvel-Eibrink, G. Kaspers, E. van Dulmen-den Broeder, Raphaële R L van Litsenburg   +11 more
semanticscholar   +1 more source

Characteristics of people living in Italy after a cancer diagnosis in 2010 and projections to 2020 [PDF]

, 2018
BACKGROUND: Estimates of cancer prevalence are widely based on limited duration, often including patients living after a cancer diagnosis made in the previous 5 years and less frequently on complete prevalence (i.e., including all patients regardless of
Botta, Laura, Buzzoni, Carlotta, Caiazzo, Anna Luisa, Candela, Giuseppa, Capocaccia, Riccardo, Caruso, Bianca, Casella, Claudia, Castaing, Marine, De Angelis, Roberta, Falcini, Fabio, Fanetti, Anna Clara, Ferretti, Stefano, Francisci, Silvia, Fusco, Mario, Giacomin, Adriano, Gigli, Anna, Gola, Gemma, Guzzinati, Stefano, Mangone, Lucia, Maso, Luigino Dal, Mazzoleni, Guido, Michiara, Maria, Pala, Filomena, Panato, Chiara, Pannozzo, Fabio, Ricci, Paolo, Rudisi, Giuseppa, Rugge, Massimo, Russo, Antonio Giampiero, Sardo, Antonella Sutera, Sensi, Flavio, Serraino, Diego, Stracci, Fabrizio, Tagliabue, Giovanna, Tisano, Francesco, Tumino, Rosario, Virdone, Saverio, Zorzi, Manuel   +37 more
core   +2 more sources

Neurocognitive Outcomes and Interventions in Long-Term Survivors of Childhood Cancer.

Journal of Clinical Oncology, 2018
Recent research has demonstrated that survivors of childhood cancer are at risk for a myriad of late effects that affect physical and mental quality of life.
K. Krull, K. Hardy, L. Kahalley, I. Schuitema, S. Kesler   +4 more
semanticscholar   +1 more source

A novel retinoblastoma therapy from genomic and epigenetic analyses. [PDF]

, 2012
Retinoblastoma is an aggressive childhood cancer of the developing retina that is initiated by the biallelic loss of RB1. Tumours progress very quickly following RB1 inactivation but the underlying mechanism is not known.
Bahrami, Armita, Benavente, Claudia A, Brennan, Rachel, Chen, Xiang, Ding, Li, Dooling, David J, Downing, James R, Dyer, Michael A, Dyson, Nicholas J, Easton, John, Ellison, David, Flores-Otero, Jacqueline, Fulton, Lucinda L, Fulton, Robert S, Gupta, Pankaj, Hong, Xin, Lu, Charles, Ma, Jing, Manning, Amity L, Mardis, Elaine R, McEvoy, Justina, Mukatira, Suraj, Mullighan, Charles, Naeve, Clayton, Neale, Geoff, Ochoa, Kerri, Pounds, Stanley, Rusch, Michael, Shurtleff, Sheila, Ulyanov, Anatoly, Wang, Jianmin, Wilson, Matthew, Wilson, Richard K, Wu, Gang, Zhang, Jinghui, Zhao, David   +35 more
core  

Polyphenon E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells [PDF]

, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Note: In this manuscript as well as in the original published version of this article the word "Polyphenon" was incorrectly spelled in the title as ...
Adrian J. Thrasher, Arturo Sala, Chow, Croce, Dale, Daniel A. Morgenstern, Giorgia Santilli, Ikeda, Izabela Piotrowska, John Anderson, Katie Pearson, Marco D'Alicarnasso, Nourredine Himoudi, Olesya Chayka, Sandra Cantilena   +14 more
core   +2 more sources

Molecular networks of hepatoblastoma predisposition and oncogenesis in Beckwith‐Wiedemann syndrome

Hepatology Communications, 2022
Beckwith‐Wiedemann Syndrome (BWS) is the most common human overgrowth disorder caused by structural and epigenetic changes to chromosome 11p15. Patients with BWS are predisposed to developing hepatoblastoma (HB).
Natali S. Sobel Naveh, Emily M. Traxler, Kelly A. Duffy, Jennifer M. Kalish   +3 more
doaj   +1 more source

Diabetes and Metabolic Syndrome in Survivors of Childhood Cancer

Hormone Research in Paediatrics, 2019
Endocrine complications, including diabetes and metabolic syndrome, are highly prevalent in childhood cancer survivors. These metabolic derangements may contribute to survivors’ risk of excess cardiovascular morbidity and premature mortality. This review
D. Friedman, E. Tonorezos, P. Cohen
semanticscholar   +1 more source