Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun +27 more
wiley +1 more source
Investigation of Melatonin Incorporated CMC-Gelatin Based Edible Coating on the Alleviation of Chilling Injury Induced Pericarp Browning in Longkong. [PDF]
Venkatachalam K +3 more
europepmc +1 more source
Personalized Network‐Guided Neuromodulation Enhances Human Working Memory
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan +13 more
wiley +1 more source
Quantifying Chilling Injury on the Photosynthesis System of Strawberries: Insights from Photosynthetic Fluorescence Characteristics and Hyperspectral Inversion. [PDF]
Jiang N, Yang Z, Luo J, Wang C.
europepmc +1 more source
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu +10 more
wiley +1 more source
Effect of Glycine Betaine on Chilling Injury in Eggplant Peel Revealed by FTIR Spectroscopy. [PDF]
Guijarro-Fuertes M +7 more
europepmc +1 more source
Proteomic and metabolomic studies on chilling injury in peach and nectarine. [PDF]
Lurie S.
europepmc +1 more source
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi +15 more
wiley +1 more source
Study on Characteristics and Lignification Mechanism of Postharvest Banana Fruit during Chilling Injury. [PDF]
Xiao L +6 more
europepmc +1 more source
Effect of methyl jasmonate and salicyclic acid on chilling injury of 'eureka' lemons.
Thesis (M.Sc.Agric.)-University of KwaZulu-Natal, Pietermaritzburg, 2010.South Africa is the second largest exporter of citrus fruit in the world. There has recently emerged a strong demand for lemons in the world market due to their nutritional value,
Siboza, Xolani Irvin.
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