Results 141 to 150 of about 311,648 (345)

Use of enzyme-linked immunosorbent assays with chimeric fusion proteins to titrate antibodies against Epstein-Barr virus nuclear antigen 1 [PDF]

, 1992
Naoki Inoue, Jun Kuranari, Shizuko Harada, Haruhiko Nakajima, Masashi Ohbayashi, Yoshie Nakamura, N. Miyasaka, Kunio Ezawa, Fumihiko Ban, Kazuhiro Yanagi   +9 more
openalex   +1 more source

Mutant B2M‐HLA‐E and B2M‐HLA‐G fusion proteins protects universal chimeric antigen receptor‐modified T cells from allogeneic NK cell‐mediated lysis

, 2021
Yelei Guo, Beilei Xu, Zhiqiang Wu, Jian Bo, Chuan Tong, Deyun Chen, Jin Wang, Haoyi Wang, Yao Wang, Weidong Han   +9 more
openalex   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

Advanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield, Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Joa Yun, Jesse Kirkpatrick, David Mankus, Margaret E. Bisher, Abigail K.R. Lytton‐Jean, Z. Gordon Jiang, David D. Lee, Christopher S. Chen, Sangeeta N. Bhatia   +13 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Inhibition of SARS-CoV-2 3CL protease by the anti-viral chimeric protein RetroMAD1. [PDF]

Sci Rep, 2023
Chan LC, Mat Yassim AS, Ahmad Fuaad AAH, Leow TC, Sabri S, Radin Yahaya RS, Abu Bakar AMS.   +6 more
europepmc   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Orf virus DNA vaccines expressing ORFV 011 and ORFV 059 chimeric protein enhances immunogenicity [PDF]

, 2011
Kui Zhao, Wenqi He, Wei Gao, Huijun Lu, Tiesuo Han, Jing Li, Ximu Zhang, Bingbing Zhang, Gaili Wang, Gaoli Su, Zhihui Zhao, Deguang Song, Feng Gao   +12 more
openalex   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Immunization of mice with chimeric protein-loaded aluminum hydroxide and selenium nanoparticles induces reduction of Brucella melitensis infection in mice. [PDF]

Clin Exp Vaccine Res, 2023
Goudarzi T, Abkar M, Zamanzadeh Z, Fasihi-Ramandi M.   +3 more
europepmc   +1 more source

Supplementary Figure Legends 1-4, Tables Legends 1-8 from A Better Immune Reaction to Erbb-2 Tumors Is Elicited in Mice by DNA Vaccines Encoding Rat/Human Chimeric Proteins [PDF]

, 2023
Elena Quaglino, Cristina Mastini, Augusto Amici, Cristina Marchini, Manuela Iezzi, Stefania Lanzardo, Carla De Giovanni, Maura Montani, Pier‐Luigi Lollini, Giuseppe Masucci, Guido Forni, Federica Cavallo   +11 more
openalex   +1 more source