Results 241 to 250 of about 311,648 (345)

Anti-viral chimeric protein RetroMAD1™ potently block SARS-CoV-2 viral entry and propagation

, 2023
Chan L, Yassim ASM, Leow TC, Sabri S, Yahaya RSR, Bakar AMSA.   +5 more
europepmc   +1 more source

High-efficiency gene transfer by adenovirus coupled to DNA-polylysine complexes [PDF]

, 1992
Agarwal, Santosh, Birnstiel, Max L., Cotten, Matt, Curiel, David T., Hu, P.-C., Li, C.-M., Loechel, S., Wagner, Ernst   +7 more
core   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

IgG Isotypes Targeting a Recombinant Chimeric Protein of Trypanosoma cruzi in Different Clinical Presentations of Chronic Chagas Disease. [PDF]

Am J Trop Med Hyg
Serrano IM, Ribeiro G, Santos RS, Cruz JS, Lanza FC, Santos EFD, Almeida MC, Soares JFS, Luquetti AO, Celedon PAF, Zanchin NIT, Santos FLN, Reis MGD.   +12 more
europepmc   +1 more source

Characterization and purification of pentameric chimeric protein particles using asymmetric flow field-flow fractionation coupled with multiple detectors. [PDF]

Anal Bioanal Chem, 2021
Kotoucek J, Hezova R, Vrablikova A, Hubatka F, Kulich P, Macaulay S, Roessner D, Raska M, Psikal I, Turanek J.   +9 more
europepmc   +1 more source

Synthesis of growth hormone-prolactin chimeric proteins and processing mutants by the exchange and deletion of genomic exons.

, 1986
SA Liebhaber, Jharna Ray, Nancy E. Cooke
openalex   +1 more source

Novel chimeric proteins mimicking SARS-CoV-2 spike epitopes with broad inhibitory activity

, 2022
Mario Cano‐Muñoz, Daniel Polo-Megías, A. Cámara-Artigas, José A. Gavira, María J. López-Rodríguez, Géraldine Laumond, Sylvie Schmidt, Julien Demiselle, Seiamak Bahram, Christiane Moog, Francisco Conejero‐Lara   +10 more
openalex   +1 more source

TopCas: Topology‐Gated Cas12a via DNA‐RNA Chimeric Circular crRNA for Amplification‐Free Nucleic Acid Detection and Conditional Gene Editing

Advanced Science, EarlyView.
The TopCas platform utilizes an engineered DNA‐RNA chimeric circular crRNA to establish topology‐gated control over CRISPR‐Cas12a activity, enabling target‐triggered self‐catalytic amplification (preamplification‐free). This system seamlessly integrates highly sensitive molecular diagnostics with conditionally controlled gene editing, demonstrating ...
Shun Zhang, Wen Sun, Ting Xiao, Yali Wang, Xianlan Wu, Huiyou Chen, Ming Chen, Jun Zhang   +7 more
wiley   +1 more source

Influenza Chimeric Protein (3M2e-3HA2-NP) Adjuvanted with PGA/Alum Confers Cross-Protection against Heterologous Influenza A Viruses. [PDF]

J Microbiol Biotechnol, 2021
Kwak C, Nguyen QT, Kim J, Kim TH, Poo H.
europepmc   +1 more source

Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance

Advanced Science, EarlyView.
Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes, Xiaokang Jin, Miguel A. Campos, Chen Zhou, Xiaoyu Zhang   +4 more
wiley   +1 more source