Results 21 to 30 of about 31,237 (196)
Haematologica, 2009 Background Thalassemia major can be cured with allogeneic hematopoietic stem cell transplantation. Persistent mixed chimerism develops in around 10% of transplanted thalassemic patients, but the biological mechanisms underlying this phenomenon are poorly
Giorgia Serafini +10 more
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Haematologica, 2009 Analysis of donor chimerism is an important diagnostic tool to assess the risk of relapse after allogeneic stem cell transplantation, especially in patients lacking a specific marker suitable for monitoring of minimal residual disease.
Martin Bornhäuser +17 more
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Haematologica, 2020 Although studies of mixed chimerism following hematopoietic stem cell transplantation in patients with sickle cell disease (SCD) may provide insights into the engraftment needed to correct the disease and into immunological reconstitution, an extensive ...
Alessandra Magnani +19 more
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Cell Transplantation, 2010 Hematopoietic chimerism resulting from prenatal marrow transplantation does not consistently result in allotolerance for unidentified causes. In a C57BL/6-into-FVB/N murine model, we transplanted T-cell-depleted adult marrow on gestational day 14 to ...
Jeng-Chang Chen M.D. +8 more
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eJHaem, 2022 Relapse is a major cause of treatment failure after hematopoietic stem cell transplantation (HSCT) for acute leukemia. Here, we report a monocentric retrospective study of all HSCTs for B cell acute lymphoblastic leukemia (ALL) performed during the years
Hannes Lindahl +6 more
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Frontiers in Immunology, 2018 Stable mixed hematopoietic chimerism is a robust method for inducing donor-specific tolerance with the potential to prevent rejection of donor islets in recipients with autoimmune type-1 diabetes.
Jiaxin Lin +6 more
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Chimerism and use of mesenchymal stem cells in umbilical cord blood transplantation
, 2013 We performed a retrospective single-center analysis of 50 umbilical cord blood transplantations (UCBTs), focusing on chimerism development. Complete donor chimerism (DC) was associated with acute graft-vs.-host disease (aGVHD) grades II-IV for the CD3 (+)
Berglund, S,, Uhlin, M,, Mattsson, J,
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Drawback of chimerism analysis by XY-fluorescence in situ hybridization: Deception of a relapse
Indian Journal of Medical and Paediatric Oncology, 2020 Chimerism is monitored by various methods in posttransplant patients. Interphase fluorescence in situ hybridization (FISH) for XY (sex) chromosomes is one of the methods commonly employed.
D VS Kiran Kumar +1 more
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Long-Term Stable Mixed Chimerism after Hematopoietic Stem Cell Transplantation in Patients with Non-Malignant Disease, Shall We Be Tolerant? [PDF]
PLoS ONE, 2016 Long-term stable mixed chimerism is a rare and poorly understood phenomenon post hematopoietic stem cell transplantation. This study aims to shed light on whether the two hematopoietic systems in patients with mixed chimerism remain functional ...
Arwen Stikvoort +7 more
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Frontiers in Oncology, 2022 Preemptive and therapeutic donor lymphocyte infusions (preDLI and tDLI) are widely used in relapsing and relapsed hematopoietic malignancies after allogeneic stem cell transplantation (alloSCT) to enhance the graft-versus-malignancy effect.
Michael Stadler +16 more
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