Results 21 to 30 of about 38,150 (242)
Preemptive and therapeutic donor lymphocyte infusions (preDLI and tDLI) are widely used in relapsing and relapsed hematopoietic malignancies after allogeneic stem cell transplantation (alloSCT) to enhance the graft-versus-malignancy effect.
Michael Stadler +16 more
doaj +1 more source
Chimerism following allogeneic hematopoietic stem cell transplantation
Allogenic hematopoietic stem cell transplantation (HSCT) is a potentially curative treatment for various hematological disorders. Different molecular genetics methods are useful to monitor engraftment, relapse of the underlying disease, rejection of the ...
O. V. Blau
doaj +1 more source
The accurate diagnosis of acute graft-versus-host disease following liver transplantation (LTx-aGVHD) has been hampered. Chimerism appears in the majority of recipients after LT and its significance in the diagnosis of LTx-aGVHD has not been clearly ...
Fei Xue +5 more
doaj +1 more source
Background: This study investigated the influence of two conditioning regimens on the chimerical status of 104 patients with acquired severe aplastic anemia.
Marcia Quiroga +5 more
doaj +1 more source
Long-Term Stable Mixed Chimerism after Hematopoietic Stem Cell Transplantation in Patients with Non-Malignant Disease, Shall We Be Tolerant? [PDF]
Long-term stable mixed chimerism is a rare and poorly understood phenomenon post hematopoietic stem cell transplantation. This study aims to shed light on whether the two hematopoietic systems in patients with mixed chimerism remain functional ...
Arwen Stikvoort +7 more
doaj +1 more source
Analysis of donor chimerism is an important diagnostic tool to assess the risk of relapse after allogeneic stem cell transplantation, especially in patients lacking a specific marker suitable for monitoring of minimal residual disease.
Martin Bornhäuser +17 more
doaj +1 more source
Background Thalassemia major can be cured with allogeneic hematopoietic stem cell transplantation. Persistent mixed chimerism develops in around 10% of transplanted thalassemic patients, but the biological mechanisms underlying this phenomenon are poorly
Giorgia Serafini +10 more
doaj +1 more source
Immune Reconstitution Kinetics following Intentionally Induced Mixed Chimerism by Nonmyeloablative Transplantation. [PDF]
Establishing mixed chimerism is a promising approach for inducing donor-specific transplant tolerance. The establishment and maintenance of mixed chimerism may enable long-term engraftment of organ transplants while minimizing the use of ...
Nayoun Kim +9 more
doaj +1 more source
Hematopoietic chimerism resulting from prenatal marrow transplantation does not consistently result in allotolerance for unidentified causes. In a C57BL/6-into-FVB/N murine model, we transplanted T-cell-depleted adult marrow on gestational day 14 to ...
Jeng-Chang Chen M.D. +8 more
doaj +1 more source
Drawback of chimerism analysis by XY-fluorescence in situ hybridization: Deception of a relapse
Chimerism is monitored by various methods in posttransplant patients. Interphase fluorescence in situ hybridization (FISH) for XY (sex) chromosomes is one of the methods commonly employed.
D VS Kiran Kumar +1 more
doaj +1 more source

