Results 111 to 120 of about 5,931 (188)
Polycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene [PDF]
Polycomb proteins play key roles in mediating epigenetic modifications that occur during cell differentiation. The Polycomb repressive complex 2 (PRC2) mediates the tri-methylation of histone H3 lysine 27 (H3K27me3).
Amat +76 more
core +3 more sources
Heat*seq: compare your HTS expreiment with RNAseq/ChIPseq/CAGE public datasets
With the establishment of better protocols and decreasing costs, high-throughput sequencing experiments such as RNA-seq or ChIP-seq are now accessible even to small experimental laboratories. However, comparing one or few experiments generated by an individual lab to the vast amount of relevant data available in public domain might be hindered due to ...
openaire +1 more source
The Transcription Factor NFATc1 Supports the Rejection of Heterotopic Heart Allografts
The immune suppressants cyclosporin A (CsA) and tacrolimus (FK506) are used worldwide in transplantation medicine to suppress graft rejection. Both CsA and FK506 inhibit the phosphatase calcineurin (CN) whose activity controls the immune receptor ...
Johannes Baur +12 more
doaj +1 more source
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
RACS: Rapid Analysis of ChIP-Seq data for contig based genomes
Background: Chromatin immunoprecipitation coupled to next generation sequencing (ChIP-Seq) is a widely used technique to investigate the function of chromatin-related proteins in a genome-wide manner. ChIP-Seq generates large quantities of data which can
Fillingham, Jeffrey +3 more
core +1 more source
A Perspective on the Enhancer Dependent Bacterial RNA Polymerase
Here we review recent findings and offer a perspective on how the major variant RNA polymerase of bacteria, which contains the sigma54 factor, functions for regulated gene expression.
Buck, M, Zhang, N
core +2 more sources
Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors. [PDF]
In vitro gametogenesis is the process of making germline cells from human pluripotent stem cells. The foundation of this model is the quality of the first progenitors called primordial germ cells (PGCs), which in vivo are specified during the peri ...
Aslanyan, Marianna +11 more
core
Analysis of a collection of ChIPseq experiments with the ChromHMM program
El volumen de información NGS que está disponible para la comunidad científica para estudiar la regulación de genes está en constante crecimiento, por lo que el análisis de estos datos más complejos. Aquí se exploró el uso de la segmentación de la cromatina Métodos, como ChromHMM, para resolver el problema en escenarios particulares. Así, se obtuvieron
openaire +1 more source
Histone methyltransferase DOT1L differentially affects the development of dendritic cell subsets. [PDF]
Bouma RG +14 more
europepmc +2 more sources

