Results 61 to 70 of about 75,340 (210)

Lipase catalysed kinetic resolution of racemic 1,2-diols containing a chiral quaternary center [PDF]

, 2018
Optically active 1,2-diols are valuable buildings blocks in organic synthesis. In the present paper, a set of racemic 1,2-diols with an ester functional group are prepared, starting from -ketoesters in a three-step procedure with moderate yields.
Gonzalo Calvo, Gonzalo de
core   +2 more sources

Heterogenisation of ketone catalysts within mesoporous supports for asymmetric epoxidation

, 2013
The synthesis of the first mesoporous silica (150 Å) anchored carbohydrate-derived chiral ketone is described. This new heterogeneous catalyst has been shown to be effective in the asymmetric epoxidation of olefins by oxone.
Adam, Aggarwal, Amadori, Amadori, Armstrong, Beckwith, Bellamy, Bloch, Caprio, Chadwick, Cho, Corey, Denmark, Denmark, Denmark, Dondoni, Farina, Frohn, Goeddel, Heitbaum, Hutchings, Jacobsen, Johansson Seechurn, Johnson, Johnson, Jones, Katsuki, McMorn, Page, Page, Pedragosa-Moreau, Raja, Raynor, Ren, Romesberg, Ross, Sartori, Shephard, Shu, Song, Stearman, Thomas, Thomas, Thomas, Tian, Tian, Tian, van den Broek, Wang, Wang, Wang, Wang, Wong, Wong, Xia, Xiong, Xuereb, Yang, Yang, Zhao, Zhu   +60 more
core   +1 more source

Separation of 4-substituted 5-methylpiracetam stereoisomers on polysaccharide-based chiral stationary phases

Journal of Chromatography Open
Monitoring of stereoisomer content in samples containing chiral compounds with multiple chiral centers is an important and challenging task in chiral liquid chromatography.
H. Kažoka, B. Turovska, T. Upmanis
doaj   +1 more source

Focus on chirality of HIV-​1 non-​nucleoside reverse transcriptase inhibitors [PDF]

, 2016
Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
core   +2 more sources

Improved Achiral and Chiral HPLC-UV Analysis of Ruxolitinib in Two Different Drug Formulations

Separations, 2020
In this paper, two new reversed-phase (RP) HPLC-UV methods enabling the quantitative achiral and chiral analysis of ruxolitinib in commercial tablets (containing 20 mg of active pharmaceutical ingredient, API) and not commercially available galenic ...
Alessandro Di Michele, Aurélie Schoubben, Ina Varfaj, Alessandro D’Arpino, Laura Mercolini, Roccaldo Sardella, Maurizio Ricci, Enrico Tiacci   +7 more
doaj   +1 more source

Nitrene Transfer Catalyzed by a Non-Heme Iron Enzyme and Enhanced by Non-Native Small-Molecule Cofactors [PDF]

, 2019
Transition-metal catalysis is a powerful tool for the construction of chemical bonds. Here we show that a non-heme iron enzyme can catalyze olefin aziridination and nitrene C–H insertion, and that these activities can be improved by directed evolution ...
Arnold, Frances H., Goldberg, Nathaniel, Knight, Anders M., Zhang, Ruijie   +3 more
core   +1 more source

Fases estacionárias quirais para cromatografia líquida de alta eficiência Chiral stationary phases for high-performance liquid chromatography

Química Nova, 2010
The development of Chiral Stationary Phases (CSPs) for high performance liquid chromatography has been studied by various researches around the world, especially, since 1980.
Tiago de Campos Lourenço, Neila Maria Cassiano, Quezia B. Cass   +2 more
doaj   +1 more source

Chiral separation in microflows [PDF]

, 2005
Molecules that only differ by their chirality, so called enantiomers, often possess different properties with respect to their biological function. Therefore, the separation of enantiomers presents a prominent challenge in molecular biology and belongs ...
A. J. Lichtenberg, D. Figeys, J. K. G. Dhont, Marcin Kostur, Michael Schindler, Peter Hänggi, Peter Talkner, R. D. Astumian, S. Ahuja   +8 more
core   +2 more sources

Funkcionális és gemini tenzidek önrendeződésének jellemzése tömbfázisban és szilárd/folyadék határfelületen [PDF]

, 2010
Az SZTE Kolloidkémiai Tanszékén közel három évtizede folynak felületaktív anyagokkal kapcsolatos kutatások. E kutatómunka magába foglalja a kationcserélő agyagásványok organofilizálását kationos tenzidekkel; anioncserélő réteges szerkezetű kettős ...
Páhi Barbara Annamária
core  

Phosphoramidite Gold(I)-Catalyzed Diastereo- and Enantioselective Synthesis of 3,4-Substituted Pyrrolidines [PDF]

, 2011
In this article the utility of phosphoramidite ligands in enantioselective AuI catalysis was explored in the development of highly diastereo- and enantioselective AuI-catalyzed cycloadditions of allenenes.
Benitez, Diego, Goddard, William A., III, González, Ana Z., Tkatchouk, Ekaterina, Toste, F. Dean   +4 more
core   +3 more sources