Results 11 to 20 of about 4,646,169 (243)
Evaluation and Application of Stationary Phase Selectivity for Drug Analysis [PDF]
Despite the wide range of HPLC stationary phases available for reversed-phase high-performance liquid chromatography (RP-HPLC) and the in-depth studies using probes to highlight differences between them, there is very little in the way of stationary ...
Perera, R. Wimal H.
core +6 more sources
Application of Natural and Modified Biomacromolecules in Miniaturised Separative Analytical Techniques [PDF]
In pharmaceutical R & D, drug stereochemistry, and consequently the rotation of enantiomers, is very important. Because they act as chiral selectors in vivo, biomacromolecules have been extensively used as chiral selectors for the liquid chromatographic (
Salmon, Andrew B
core +6 more sources
Dual Nickel/Photoredox-Catalyzed Regio- and Enantioselective Alkenylation of Epoxides. [PDF]
Adv Sci (Weinh)Ni/photoredox‐catalyzed stereoconvergent cross‐electrophile coupling of racemic epoxides with alkenyl bromides is described, affording β‐alkenyl products with up to 95% ee, excellent E‐selectivity, and complete regiocontrol. These versatile intermediates enable diverse chiral synthons; mechanistic studies suggest a halide ring‐opening followed by ...
Lan H, Jin S, Xu ZD, Li G, Wang D.
europepmc +2 more sources
Chiral stationary phases and applications in gas chromatography
Chirality, 2022 AbstractChiral compounds are ubiquitous in nature and play a pivotal role in biochemical processes, in chiroptical materials and applications, and as chiral drugs. The analysis and determination of the enantiomeric ratio (er) of chiral compounds is of enormous scientific, industrial, and economic importance.
Gloria Betzenbichler +5 more
openaire +3 more sources
Marine Drugs, 2022 Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a–c and rac-8a–c, named marinoepoxides, is described.
Anđela Buljan, Marin Roje
doaj +1 more source
Chiral separation by ligand-exchange
Macedonian Journal of Chemistry and Chemical Engineering, 2011 The principle of chiral ligand-exchange, introduced by Davankov, has become a widely used technique for chiral separation in both chromatography and in electromigration techniques.
Martin G Schmid, Gerald Gübitz
doaj +1 more source
Molecules, 2021 Polysaccharides, oligosaccharides, and their derivatives, particularly of amylose, cellulose, chitosan, and β-cyclodextrin, are well-known chiral selectors (CSs) of chiral stationary phases (CSPs) in chromatography, because they can separate a wide range
Cuong Viet Bui +2 more
doaj +1 more source
Adsorption Science & Technology, 2018 Recently, we reported a new chiral stationary phase prepared using β-cyclodextrin functionalized with aromatic ionic liquid which is aimed to enhance the performance of enantioseparation of flavonoids and β-blockers.
Nurul Yani Rahim +2 more
doaj +1 more source
Journal of Taibah University for Science, 2021 The present work aims to present two new concepts concerned with chiral separation. First, chiral separation of some enantiomeric drugs, using micelle-based liquid chromatography without any chiral selector, whether in the stationary phase or the mobile ...
M. E. K. Wahba +2 more
doaj +1 more source
Molecules, 2021 Daptomycin, a macrocyclic antibiotic, is here used as a new chiral selector in preparation of chiral stationary phase (CSP) in a recently prepared polymer monolithic capillary.
Ali Fouad +5 more
doaj +1 more source