Results 21 to 30 of about 4,646,169 (243)
Effects of Temperature and Mobile Phase Condition on Chiral Recognition of Poly(l-phenylalanine) Chiral Stationary Phase [PDF]
, 2011 Characteristics of the chiral stationary phase with poly(l-phenylalanine) peptide selector, which was in α-helical state, was reported. Since environmental factors affect peptide conformation, the changes in enantioselectivity were examined depending on ...
Ohba, Yoshihito +13 more
core +1 more source
Preparation and characterization of poly(l-phenylalanine) chiral stationary phases with varying peptide length. [PDF]
, 2008 Three new chiral stationary phases with different lengths of l-phenylalanine peptide were prepared by solid-phase synthesis with tert-butoxycarbonyl (Boc)-l-phenylalanine on silica.
Ohba, Yoshihito +7 more
core +1 more source
A High-Resolution Magic Angle Spinning NMR Study of the Enantiodiscrimination of 3,4-Methylenedioxymethamphetamine (MDMA) by an Immobilized Polysaccharide-Based Chiral Phase. [PDF]
PLoS ONE, 2016 This paper reports the investigation of the chiral interaction between 3,4-methylenedioxy-methamphetamine (MDMA) enantiomers and an immobilized polysaccharide-based chiral phase.
Juliana C Barreiro +4 more
doaj +1 more source
Molecules, 2013 Enantioseparation is largely based on the formation of transitional complexes, the solvation species, the stationary phase configurations or the diastereomeric complexes formed by analytes and the chiral stationary phase.
Hong-Xun Guo, Steven Wu, Jingshun Sun
doaj +1 more source
Molecules, 2023 The enantioselective potential of two macrocyclic glycopeptide-based chiral stationary phases for analysis of 28 structurally diverse biologically active compounds such as derivatives of pyrovalerone, ketamine, cathinone, and other representatives of ...
Denisa Folprechtová +3 more
doaj +1 more source
DFT-assisted rational design of salan ligands for highly enantioselective Zr-salan-catalyzed hydroxylation of cyclic <i>β</i>-keto esters. [PDF]
Smart MolGuided by DFT calculations, the design of novel C1‐symmetric salan ligands without the involvement of Suzuki coupling was achieved, and the preparation of α‐hydroxy‐β‐ketoesters in 99% yield and 99% ee was realized under low catalyst loading. Abstract In this work, a structurally simple, inexpensive, and readily accessible Zr–salan catalytic system was
Ma C +9 more
europepmc +2 more sources
Journal of Pharmaceutical Analysis, 2012 The enantiomers separation of thirteen drugs collected in Ch.P2010 was performed on chiral stationary phase of cellulose ramification (chiralpak OD and chiralpak OJ) by high performance liquid chromatographic (HPLC) methods, which included ibuprofen (C1),
Ying Zhou +7 more
doaj +1 more source
The Separation of Cannabinoids on Sub-2 µm Immobilized Polysaccharide Chiral Stationary Phases
Pharmaceuticals, 2021 The increased use and applicability of Cannabis and Cannabis-derived products has skyrocketed over the last 5 years. With more and more governing bodies moving toward medical and recreational legalization, the need for robust and reliable analytical ...
Takafumi Onishi, Weston J. Umstead
doaj +1 more source
Green Analytical ChemistryA novel chiral monolithic nano-column was developed for the enantioseparation of chiral drugs by nano-liquid chromatography (nano-LC). The monolithic capillary with 50 µm i.d. was first prepared by an in-situ polymerization using butyl methacrylate (BuMA)
Cemil Aydoğan
doaj +1 more source
Aldol Reactions of Axially Chiral 5-Methyl-2-(o-aryl)imino-3-(o-aryl)-thiazolidine-4-ones
Molecules, 2016 Axially chiral 5-methyl-2-(o-aryl)imino-3-(o-aryl)-thiazolidine-4-ones have been subjected to aldol reactions with benzaldehyde to produce secondary carbinols which have been found to be separable by HPLC on a chiral stationary phase.
Sule Erol Gunal, Ilknur Dogan
doaj +1 more source