Results 21 to 30 of about 5,957 (202)

A chiral metal-organic framework {(HQA)(ZnCl2)(2.5H2O)}n for the enantioseparation of chiral amino acids and drugs

Journal of Pharmaceutical Analysis, 2023
Chiral metal-organic frameworks (CMOFs) with enantiomeric subunits have been employed in chiral chemistry. In this study, a CMOF formed from 6-methoxyl-(8S,9R)-cinchonan-9-ol-3-carboxylic acid (HQA) and ZnCl2, {(HQA)(ZnCl2)(2.5H2O)}n, was constructed as ...
Xiangtai Zheng, Qi Zhang, Qianjie Ma, Xinyu Li, Liang Zhao, Xiaodong Sun   +5 more
doaj   +1 more source

Separation Of Methionine Enantiomers By Using Teicoplanin And Cyclofructan Columns

Nova Biotechnologica et Chimica, 2015
Methionine is a naturally occurring amino acid. Its enantiomeric separation by using high performance liquid chromatography on various types of chiral stationary phases was studied.
Hroboňová Katarína, Deáková Zuzana, Moravčík Jakub, Lehotay Jozef, Armstrong Daniel W., Lomenová Anna   +5 more
doaj   +1 more source

Application of Green Chiral Chromatography in Enantioseparation of Newly Synthesized Racemic Marinoepoxides

Marine Drugs, 2022
Enantioseparation of the newly synthesized series of novel quinoline-2(1H)-one epoxide structures rac-6a–c and rac-8a–c, named marinoepoxides, is described.
Anđela Buljan, Marin Roje
doaj   +1 more source

Chiral separation by ligand-exchange

Macedonian Journal of Chemistry and Chemical Engineering, 2011
The principle of chiral ligand-exchange, introduced by Davankov, has become a widely used technique for chiral separation in both chromatography and in electromigration techniques.
Martin G Schmid, Gerald Gübitz
doaj   +1 more source

Chromatographic and spectroscopic studies on β-cyclodextrin functionalized ionic liquid as chiral stationary phase: Enantioseparation of NSAIDs

Adsorption Science & Technology, 2018
Recently, we reported a new chiral stationary phase prepared using β-cyclodextrin functionalized with aromatic ionic liquid which is aimed to enhance the performance of enantioseparation of flavonoids and β-blockers.
Nurul Yani Rahim, Kheng Soo Tay, Sharifah Mohamad   +2 more
doaj   +1 more source

Estimating chiral selector potential of micelle-based mobile phases through the analysis of some enantiomeric mixtures

Journal of Taibah University for Science, 2021
The present work aims to present two new concepts concerned with chiral separation. First, chiral separation of some enantiomeric drugs, using micelle-based liquid chromatography without any chiral selector, whether in the stationary phase or the mobile ...
M. E. K. Wahba, D. El Sherbiny, D. El Wasseef   +2 more
doaj   +1 more source

Polysaccharide- and β-Cyclodextrin-Based Chiral Selectors for Enantiomer Resolution: Recent Developments and Applications

Molecules, 2021
Polysaccharides, oligosaccharides, and their derivatives, particularly of amylose, cellulose, chitosan, and β-cyclodextrin, are well-known chiral selectors (CSs) of chiral stationary phases (CSPs) in chromatography, because they can separate a wide range
Cuong Viet Bui, Thomas Rosenau, Hubert Hettegger   +2 more
doaj   +1 more source

Daptomycin: A Novel Macrocyclic Antibiotic as a Chiral Selector in an Organic Polymer Monolithic Capillary for the Enantioselective Analysis of a Set of Pharmaceuticals

Molecules, 2021
Daptomycin, a macrocyclic antibiotic, is here used as a new chiral selector in preparation of chiral stationary phase (CSP) in a recently prepared polymer monolithic capillary.
Ali Fouad, Adel A. Marzouk, Montaser Sh. A. Shaykoon, Samy M. Ibrahim, Sobhy M. El-Adl, Ashraf Ghanem   +5 more
doaj   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods. [PDF]

Chirality
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Karayavuz B, Kirmizioglu CK.
europepmc   +2 more sources

A High-Resolution Magic Angle Spinning NMR Study of the Enantiodiscrimination of 3,4-Methylenedioxymethamphetamine (MDMA) by an Immobilized Polysaccharide-Based Chiral Phase. [PDF]

PLoS ONE, 2016
This paper reports the investigation of the chiral interaction between 3,4-methylenedioxy-methamphetamine (MDMA) enantiomers and an immobilized polysaccharide-based chiral phase.
Juliana C Barreiro, Márcio W Paixão, Tiago C Lourenço, Quezia B Cass, Tiago Venâncio   +4 more
doaj   +1 more source