Results 141 to 150 of about 6,708 (181)
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Supercritical fluid assisted production of chitosan oligomers micrometric powders

Carbohydrate Polymers, 2014
Chitosan oligomers (O-chitosan) micrometric particles were produced from aqueous solution using a novel process, i.e. supercritical fluid assisted atomization introduced by hydrodynamic cavitation mixer (SAA-HCM). Hydrodynamic cavitation was introduced to enhance mass transfer and facilitate the mixing between SC-CO2 and liquid solution for fine ...
Zhe, Du   +5 more
openaire   +2 more sources

Quantitative Mass-Spectrometric Sequencing of Chitosan Oligomers Revealing Cleavage Sites of Chitosan Hydrolases

Analytical Chemistry, 2017
Partially acetylated chito-oligosaccharides (paCOS) have diverse bioactivities that turn them into promising compounds especially for medical and agricultural applications. These properties likely arise from different acetylation patterns, but determining the sequences of paCOS and producing paCOS with patterns of interest have proven difficult.
Stefan Cord-Landwehr   +5 more
openaire   +2 more sources

Dissecting the conformational determinants of chitosan and chitlac oligomers

Biopolymers, 2018
AbstractChitosan and its highly hydrophilic 1‐deoxy‐lactit‐1‐yl derivative (Chitlac) are polysaccharides with increasing biomedical applications. Aimed to unravel their conformational properties we have performed a series of molecular dynamics simulations of Chitosan/Chitlac decamers, exploring different degrees of substitution (DS) of lactitol side ...
Esteban, C.   +5 more
openaire   +3 more sources

Ultrapure chitosan oligomers as carriers for corneal gene transfer

Biomaterials, 2010
NOVAFECT chitosans are ultrapure chitosan oligomers that were recently marketed as carriers for non-viral gene therapy. There are no reports on systematic design and improvement of formulations based on NOVAFECT chitosans for gene delivery. Therefore, we have designed and characterized chitosan-DNA nanoparticles based on NOVAFECT.
Eytan A, Klausner   +4 more
openaire   +2 more sources

Separation of chitosan oligomers by immobilized metal affinity chromatography

Journal of Chromatography A, 2008
A novel approach for chitosan oligosaccharide (COS) separation by immobilized metal affinity chromatography (IMAC) based on the differences in the interactions of chelated copper (II) ions with various COS (dimers, trimers, tetramers) is described.
Frantz, Le Dévédec   +5 more
openaire   +2 more sources

Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery

Journal of Controlled Release, 1998
Chitosan is a polysaccharide that demonstrates much potential as a gene delivery system. The ability of a commercially available chitosan and depolymerized chitosan oligomers to condense plasmid was determined using TEM and microtitration calorimetry, while the diameter and stability of the resultant complexes were measured using laser light scattering.
F C, MacLaughlin   +6 more
openaire   +2 more sources

Antimicrobial activity of chitosan and a chitosan oligomer against bacterial pathogens of warmwater fish

Journal of Applied Microbiology, 2017
The antibacterial activities of chitosan (CS) and its derivative chitosan oligosaccharide lactate (COL) were evaluated against Aeromonas hydrophila, Edwardsiella ictaluri and Flavobacterium columnare, three highly pathogenic bacteria of warmwater finfish.The magnitude and mode of antimicrobial action on Gram-negative bacterial pathogens was ...
M, Yildirim-Aksoy, B H, Beck
openaire   +2 more sources

Preparation of chitosan oligomers and their antioxidant activity

European Food Research and Technology, 2006
Chitosan oligomers with different molecular weights were prepared by oxidative degradation method involving hydrogen peroxide (H2O2) and the combined degradation method using hydrogen peroxide and microwave radiation. Viscosity determination and end group analysis were applied to measure molecular weights of chitosan oligomers. Effects of concentration
Tao Sun   +3 more
openaire   +1 more source

Anti-HIV activities of novel synthetic peptide conjugated chitosan oligomers

International Journal of Biological Macromolecules, 2014
Chitosan and chitosan derived compounds are marine byproducts which have been shown to exhibit bioactivities including antibacterial, antioxidant, antidiabetic and anti-HIV. Proteins are among the most potent and selective molecules offering an endless potential of different structure and sequence preferences.
Mustafa Zafer, Karagozlu   +2 more
openaire   +2 more sources

Tissue engineering with electrospun electro-responsive chitosan-aniline oligomer/polyvinyl alcohol

International Journal of Biological Macromolecules, 2020
Mimicking the native tissue is an ultimate goal in tissue engineering. In this study, conductive chitosan was synthesized by coupling with aniline oligomers, and then conductive nanofibers were fabricated using electrospinning technique to mimic the tissue structure and properties. The conductivity of the resulting biomaterial was adjusted to ca.
Babak, Bagheri   +8 more
openaire   +2 more sources

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