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Regulation of Lymphocyte Chloride Channels
1991The chloride permeability defect which characterizes the apical membrane of secretory epithelial cells in cystic fibrosis has been difficult to study in part because of lack of accessibility of tissue for study. This problem has fostered attempts by investigators both to immortalize epithelial cell lines and to search for other cells which may serve as
P, Gardner +6 more
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Phenomics of Cardiac Chloride Channels
Comprehensive Physiology, 2013AbstractForward genetic studies have identified several chloride (Cl−) channel genes, including CFTR, ClC‐2, ClC‐3, CLCA, Bestrophin, and Ano1, in the heart. Recent reverse genetic studies using gene targeting and transgenic techniques to delineate the functional role of cardiac Cl− channels have shown that Cl− channels may contribute to cardiac ...
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Chloride channels of intracellular organelles
Current Opinion in Cell Biology, 1995Chloride channels are present in a variety of intracellular organelles (Golgi, endosomes, endoplasmic reticulum, and sarcoplasmic reticulum) where they serve largely to shunt the membrane potential created by other ion-translocating processes. Electrophysiological studies have shown that the Cl- channels of the endoplasmic and sarcoplasmic reticula ...
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Molecular determinants of pH sensing in the proton-activated chloride channel
Proceedings of the National Academy of Sciences of the United States of America, 2022James Osei-Owusu +2 more
exaly
Chloride channels in epithelia
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1988openaire +3 more sources
Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM
Nature, 2017Cristina Paulino +2 more
exaly

