Results 271 to 280 of about 3,359,139 (307)
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Chloride channels of intracellular organelles
Current Opinion in Cell Biology, 1995Chloride channels are present in a variety of intracellular organelles (Golgi, endosomes, endoplasmic reticulum, and sarcoplasmic reticulum) where they serve largely to shunt the membrane potential created by other ion-translocating processes. Electrophysiological studies have shown that the Cl- channels of the endoplasmic and sarcoplasmic reticula ...
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Chloride channel: Tail Wagging the Channel
Science's STKE, 1999Improper function of the chloride channel known as the cystic fibrosis transmembrane regulator (CFTR) is associated with debilitating diseases in humans. Conductance of the channel is regulated in a complex manner. One mechanism of regulation requires phosphorylation of the channel in the so-called regulatory or R domain, which relieves an
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The Physiology of Epithelial Chloride Channels
Hospital Practice, 1989These highly regulated channels have a rate-limiting function in secretory activity. Recent research has suggested that the regulation of chloride transport is the likely locus of the defect in cystic fibrosis and has contributed to a fuller understanding of the control of ion channels and their role in fluid and electrolyte balance.
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Chloride channels in epithelia
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1988openaire +3 more sources
X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity
Nature, 2002R. Dutzler +4 more
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TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity
Science, 2008A. Caputo +9 more
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Structures and pH-sensing mechanism of the proton-activated chloride channel
Nature, 2020Zheng Ruan, Wei Lu, Wei Lu
exaly
Development and validation of a potent and specific inhibitor for the CLC-2 chloride channel
Proceedings of the National Academy of Sciences of the United States of America, 2020Merritt Maduke +2 more
exaly

