Results 31 to 40 of about 266,501 (296)

Tetramethylenedisulfotetramine [PDF]

open access: yes, 2014
Tetramethylenedisulfotetramine (CAS 80-12-6), commonly referred to as TETS, was first synthesized in 1933 as a condensation product of sulfamide and formaldehyde. TETS was subsequently used as a rodenticide until banned worldwide in 1991.
Banks, CN   +3 more
core   +1 more source

Ion channel expression in the developing enteric nervous system. [PDF]

open access: yesPLoS ONE, 2015
The enteric nervous system arises from neural crest-derived cells (ENCCs) that migrate caudally along the embryonic gut. The expression of ion channels by ENCCs in embryonic mice was investigated using a PCR-based array, RT-PCR and immunohistochemistry ...
Caroline S Hirst   +10 more
doaj   +1 more source

Glutamate-gated Chloride Channels [PDF]

open access: yesJournal of Biological Chemistry, 2012
Glutamate-gated chloride channels (GluCls) are found only in protostome invertebrate phyla but are closely related to mammalian glycine receptors. They have a number of roles in these animals, controlling locomotion and feeding and mediating sensory inputs into behavior.
openaire   +2 more sources

Role of physiological ClC-1 Cl- ion channel regulation for the excitability and function of working skeletal muscle. [PDF]

open access: yes, 2016
Electrical membrane properties of skeletal muscle fibers have been thoroughly studied over the last five to six decades. This has shown that muscle fibers from a wide range of species, including fish, amphibians, reptiles, birds, and mammals, are all ...
Chen, Tsung-Yu   +4 more
core   +1 more source

Positive modulation of the TMEM16B mediated currents by TRPV4 antagonist

open access: yesBiochemistry and Biophysics Reports, 2021
Calcium-activated chloride channels (CaCCs) play important roles in many physiological processes and their malfunction is implicated in diverse pathologies such as cancer, asthma, and hypertension.
Adan Hernandez   +3 more
doaj   +1 more source

Modulation of the hepatocyte rough endoplasmic reticulum single chloride channel by nucleotide-Mg 2+ interaction

open access: yes, 2012
The effect of nucleotides on single chloride channels derived from rat hepatocyte rough endoplasmic reticulum vesicles incorporated into bilayer lipid membrane was investigated.
Ashrafpour, M.   +4 more
core   +1 more source

Exploring glutamate-gated chloride channels in cancer cells: A narrative review on a hypothetical mechanism underpinning the anticancer effects of antiparasitic drugs

open access: yesСибирский научный медицинский журнал
Chloride channels play a fundamental role in cellular homeostasis, influencing ion balance, pH regulation, and apoptotic signaling. While glutamate-gated chloride channels (GluCl) are traditionally restricted to invertebrates, recent evidence suggests ...
M. M. Akl, A. Ahmed
doaj   +1 more source

Safety and efficacy of a combined paste formulation of a botanical extract of the latex of Croton lechleri (SB-300, Neonorm foal™) with probiotics for the treatment of watery diarrhea in nursing foals

open access: yesAnalecta Veterinaria, 2017
La diarrea es un desorden común en potrillos lactantes, y no se dispone de antidiarreicos antisecretorios específicos. El objetivo del estudio fue evaluar la seguridad y eficacia de una formulación en pasta con cubierta entérica del extracto botánico ...
Siobhan McAuliffe   +6 more
doaj   +1 more source

A small synthetic molecule functions as a chloride–bicarbonate dual-transporter and induces chloride secretion in cells [PDF]

open access: yes, 2016
A C2 symmetric small molecule composed of L-phenylalanine and isophthalamide was found to function as a Cl−/HCO3− dual transporter and self-assemble into chloride channels.
Ko, WH   +5 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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