Results 141 to 150 of about 93,237 (289)

Development of a Green Capillary Electrophoresis Method for Determining and Quality Control of Dapagliflozin: An Oral Hypoglycemic Agent

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT A green method by capillary electrophoresis (CE) is described for the first time for the determination of dapagliflozin (DAPA), an oral hypoglycemic drug approved for the treatment of Type 2 diabetes mellitus. The effects of different analytical conditions were evaluated, including the concentration and pH of the background electrolyte (BGE ...
Lívia Maronesi Bueno   +4 more
wiley   +1 more source

High-Dose Chloroquine for Treatment of Chloroquine-ResistantPlasmodium falciparumMalaria [PDF]

open access: bronze, 2015
Johan Ursing   +4 more
openalex   +1 more source

Systematic review and meta-analysis of efficacy and safety of hydroxychloroquine and chloroquine in the treatment of COVID-19

open access: gold, 2021
Niti Mittal   +6 more
openalex   +1 more source

Modulating Lysine Crotonylation in Ulcerative Colitis Maintains Mitochondrial Homeostasis

open access: yesExploration, EarlyView.
NaCr promotes KCr to impede the inflammatory progression of ulcerative colitis. KCr induces mitophagy by activating the PINK1/PARKIN pathway to restrict NLRP3 inflammasome activation, thereby decreasing the production and release of various inflammatory cytokines, such as IL‐1β and TNF‐α. KCr induces mitophagy and inhibits NLRP3 inflammasome activation
Tongtong Liu   +7 more
wiley   +1 more source

Long‐Term Dermoscopic Evolution of Reticular Erythematous Mucinosis: Case Report

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Reticular erythematous mucinosis is a rare dermatosis with a challenging diagnosis. To date, its dermoscopic features have not been well characterised in the literature. Only a limited number of case reports have described dermoscopic findings that may be indicative of the disorder, including the presence of dotted and linear vessels, as well ...
Grażyna Kamińska‐Winciorek   +4 more
wiley   +1 more source

Experimental Evidence That Blood Parasite Infection Affects Incubation Patterns in a Cavity‐Nesting Songbird

open access: yesIntegrative Zoology, EarlyView.
Chronic blood parasite infections in wild birds can affect their incubation behavior. In pied flycatchers, females with reduced parasite infections incubated for longer than control females. Despite behavioral changes, no immediate effects on fitness were observed.
Marina García‐del Río   +5 more
wiley   +1 more source

APP Induces AICD‐Mediated Autophagy‐Dependent Axon Degeneration

open access: yesAging Cell, EarlyView.
In the adult Drosophila wing, amyloid precursor protein (APP) promotes axon degeneration through its intracellular domain (AICD) via an autophagy‐dependent pathway. The transcription factor dFoxO is essential for APP/AICD‐induced autophagy and plays a critical role in mediating the resulting neurodegeneration.
Jingjing Luo   +12 more
wiley   +1 more source

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy   +16 more
wiley   +1 more source

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