Results 161 to 170 of about 85,533 (259)

Dry Deposition Strategies for MALDI–MS Imaging: Principles, Advances and Emerging Applications

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Matrix‐assisted laser desorption/ionisation mass spectrometry imaging (MALDI–MSI) has become a pivotal tool in biomedical research, enabling untargeted, spatially resolved analysis of molecular species in complex biological tissues. Among the critical steps in MALDI–MSI workflows, matrix deposition significantly influences sensitivity, spatial
Toufik Mahamdi, Oscar Yanes
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

FKBP9 Enhances Colon Cancer Cell Proliferation by Inhibiting GPX4‐Mediated Ferroptosis

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
The significance of FKBP9 as a therapeutic target in colon cancer treatment, providing new avenues for strategies aimed at sensitizing cancer cells to ferroptosis and improving patient outcomes. ABSTRACT Colorectal cancer, a major health issue worldwide, exhibits intricate molecular mechanisms that necessitate further exploration, particularly ...
Jianzhong Deng   +6 more
wiley   +1 more source

Targeted Genomic Surveillance Unveils Genetic Variations Linked to Regional Malaria Drug Resistance Dynamics in India. [PDF]

open access: yesOpen Forum Infect Dis
Khilari A   +8 more
europepmc   +1 more source

Depigmentation Outcomes in Pigmented Oral Lichen Planus Managed With Mycophenolate Mofetil

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Pigmented oral lichen planus (OLP) is a chronic, immune‐mediated mucosal disorder associated with dark black or brown discoloration secondary to the excess melanin deposition. This medical condition is often accompanied by the typical white (reticular) or red (erosive) OLP features and is refractory to conventional therapy. We report a case of
Tania Biswas   +5 more
wiley   +1 more source

USP5‐C‐MAF Axis Regulates Autophagy‐Dependent Neuronal Ferroptosis in Spinal Cord Injury Therapeutics

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
SCI induces significant upregulation of USP5 in neurons. The overexpressed USP5 stabilizes c‐MAF protein expression through its deubiquitinase activity, activating autophagy and accelerating the degradation of autophagic ferritin, thereby mediating neuronal ferroptosis. This ultimately leads to impaired functional recovery in SCI mice.
Shiyang Weng   +4 more
wiley   +1 more source

Antiviral Mechanisms of Justicidin B and Tuberculatin from <i>Phyllanthus brasiliensis</i> against Oropouche Virus Infection. [PDF]

open access: yesACS Omega
Bueno da Silva Menegatto M   +17 more
europepmc   +1 more source

Integrated high‐throughput phenomics and transcriptomics uncover the transcriptional mechanisms underlying rice responses to elevated CO2 concentration and cadmium stress

open access: yesiMetaOmics, Volume 3, Issue 2, June 2026.
Developing crop varieties with reduced cadmium (Cd) accumulation under elevated carbon dioxide (eCO2) requires hub gene identification and elucidation of its transcriptional mechanisms. Here, we acquired high‐throughput phenotyping of the rice cultivar Nipponbare across six key developmental stages under Cd stress and three eCO2 concentrations.
Weijun Guo   +10 more
wiley   +1 more source

Lateral hypothalamus directs stress-induced modulation of acute and psoriatic itch. [PDF]

open access: yesCell Rep
Prajapati JN   +4 more
europepmc   +1 more source

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