Results 161 to 170 of about 108,092 (308)

Identification of genetic markers of quinine partial resistance in Plasmodium falciparum. [PDF]

open access: yesNat Microbiol
Kanai M   +30 more
europepmc   +1 more source

Safety of Prenatal Anti‐Infective Use and Offspring Outcomes: A Panoramic Assessment by Indication, Drug Class, and Exposure Characteristics

open access: yesiMetaMed, EarlyView.
Based on the comprehensive, panoramic assessment of the safety of prenatal anti‐infective use across indications, drug classes, and exposure characteristics, potential safety signals associated with prenatal exposure to several widely used anti‐infective drug classes were identified, including macrolides, metronidazole, tetracyclines, sulfonamides ...
Wenling Wang   +7 more
wiley   +1 more source

Patterns of medication use among individuals with Covid-19 in Brazil: Epicovid 2.0. [PDF]

open access: yesRev Saude Publica
Buffarini R   +3 more
europepmc   +1 more source

miR‐9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Insulin secretion is a complex, vesicular transport process. Rab34 is a key regulator of intracellular vesicle transport; however, its role in insulin secretion has not yet been reported. miRNA‐9 is vital for the development and progression of the diagnosis and treatment of type 2 diabetes. This study aimed to investigate whether miR‐9 targets
Zhen‐Zhen Guo   +5 more
wiley   +1 more source

Knockdown of CREB3L4 Inhibits Autophagy and Reduces Cisplatin Resistance in Gastric Cancer Cells by Downregulating BAG3

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cisplatin resistance remains a major obstacle in the treatment of gastric cancer (GC), and autophagy has been increasingly recognized as a key cytoprotective mechanism contributing to chemoresistance. CREB3L4 is an endoplasmic reticulum membrane‐bound transcription factor that has been shown to regulate the expression of Bcl‐2 associated ...
Wen‐Ke Yin   +3 more
wiley   +1 more source

WDR72 Drives Esophageal Squamous Cell Carcinoma Progression by Inhibiting Autophagy via the PI3K/Akt/mTOR Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with a high rate of recurrence and metastasis, necessitating the identification of novel therapeutic targets. WD repeat‐containing protein 72 (WDR72) has been linked to various cancers, but its specific biological function and underlying mechanism in ESCC remain largely ...
Hao Wu, Zhong‐Xiang Jiang, Zheng Jiang
wiley   +1 more source

Malaria in Solid Organ Transplant Recipients: Transmission, Diagnosis, Geographic Patterns, and the Role of Cyclosporin. [PDF]

open access: yesPathogens
Wilczyńska W   +4 more
europepmc   +1 more source

Chloroquine [PDF]

open access: yesReactions Weekly, 2020
openaire   +1 more source

The contribution of endocytic mediators to itch transmission. [PDF]

open access: yesFront Mol Neurosci
Ferreira MA   +4 more
europepmc   +1 more source

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