Results 171 to 180 of about 85,533 (259)

Extracellular Vesicle‐Associated IL4 Displays Enhanced Anti‐Inflammatory Properties in Microglial Cells

open access: yesJournal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Neuroinflammation and neurodegeneration are strictly related phenomena, characterized by dysregulation of microglia, central nervous system (CNS) resident immune cells. Interleukin‐4 (IL4) has shown beneficial abilities to re‐establish microglial homeostasis in experimental models of CNS traumatic injury, stroke and multiple sclerosis, but its
Giulia Marostica   +11 more
wiley   +1 more source

Long‐Term Dermoscopic Evolution of Reticular Erythematous Mucinosis: Case Report

open access: yesJEADV Clinical Practice, Volume 5, Issue 2, Page 637-639, June 2026.
ABSTRACT Reticular erythematous mucinosis is a rare dermatosis with a challenging diagnosis. To date, its dermoscopic features have not been well characterised in the literature. Only a limited number of case reports have described dermoscopic findings that may be indicative of the disorder, including the presence of dotted and linear vessels, as well ...
Grażyna Kamińska‐Winciorek   +4 more
wiley   +1 more source

<i>Plasmodium falciparum</i> field isolates drug susceptibility in Mali. [PDF]

open access: yesJAC Antimicrob Resist
Maiga FO   +11 more
europepmc   +1 more source

Genomic and Transcriptomic Insights Into Salinity Tolerance in Dry Pea

open access: yesLegume Science, Volume 8, Issue 2, June 2026.
ABSTRACT Salinity is a major crop production constraint in dry pea (Pisum sativum L.), making the development of salt‐tolerant varieties essential to improve crop productivity and land‐use efficiency. The genetic mechanisms of salt tolerance in dry pea are largely unknown, and research on salt‐tolerant genes is limited.
Shailesh Raj Acharya   +11 more
wiley   +1 more source

Organoids: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li   +6 more
wiley   +1 more source

Tectochrysin Ameliorates Colitis‐Associated Colon Cancer in Mice Via the Activation of Mitophagy in Intestinal Epithelial Cells

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 11, 15 June 2026.
Tectochrysin (TEC) activates Foxo3a/Pink1/Parkin‐mediated mitophagy in intestinal epithelial cells, restoring mitochondrial homeostasis and reducing ROS, thereby ameliorating AOM/DSS‐induced colitis‐associated colon cancer (CAC) in mice. ABSTRACT Tectochrysin (TEC), a natural flavonoid, has shown efficacy in ameliorating chronic colitis.
Jikai He   +4 more
wiley   +1 more source

A homozygous CTLA-4 variant causes CTLA-4 deficiency with severe immune dysregulation. [PDF]

open access: yesJ Hum Immun
Catak MC   +17 more
europepmc   +1 more source

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao   +4 more
wiley   +1 more source

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