Hyponatraemia and hypokalaemia due to indapamide [PDF]
The document attached has been archived with permission from the editor of the Medical Journal of Australia (10 January 2008). An external link to the publisher’s copy is included.Objectives: To review Australian adverse drug reaction reports describing ...
Chapman, M.+3 more
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Background/purpose: Chlorothiazide is a well-known diuretic and an antihypertensive drug with poor solubility and permeability and thus low bioavailability.
Ahmad J. Obaidullah
doaj
Selective effect of thiazides on the human osteoblast-like cell line MG-63 [PDF]
Selective effect of thiazides on the human osteoblast-like cell line MG-63. Thiazide diuretics have been shown to decrease bone-loss rate and to improve bone mineral density in patients using this medication.
Aubin, R.+2 more
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Chlorothiazide, with the brand name Diuril, is used as a diuretic as well as an antihypertensive drug. This medicine with very slight solubility in water and low permeability is categorized in the class IV of Biopharmaceutical Classification System (BCS)
Mohammed Majrashi+5 more
doaj
– Purpose. Oral drug administration remains the most common and most convenient way used in clinical therapy. The availability of a simple, rapid, economic and reproducible in vitro method to assess drug absorption is a very helpful tool.
Mohamed Ali Lassoued+2 more
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Impact of alternative solid state forms and specific surface area of high-dose, hydrophilic active pharmaceutical ingredients on tabletability [PDF]
YesIn order to investigate the effect of using different solid state forms and specific surface area (TBET) of active pharmaceutical ingredients on tabletability and dissolution performance, the mono- and dihydrated crystalline forms of ...
Abdul Jaleel O. W.+30 more
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Impact of process variables on the micromeritic and physicochemical properties of spray-dried microparticles, part II: physicochemical characterisation of spray-dried materials [PDF]
YesObjectives In this work we investigated the residual organic solvent content and physicochemical properties of spray-dried chlorothiazide sodium (CTZNa) and potassium (CTZK) salts.
Al-Obaidi+28 more
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Use of Chlorothiazide in the Management of Central Diabetes Insipidus in Early Infancy
Management of central diabetes insipidus in infancy is challenging. The various forms of desmopressin, oral, subcutaneous, and intranasal, have variability in the duration of action.
Manish Raisingani+2 more
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Generic sample preparation combined with high-resolution liquid chromatography- time-of-flight mass spectrometry for unification of urine screening in doping-control laboratories [PDF]
A unification of doping-control screening procedures of prohibited small molecule substances—including stimulants, narcotics, steroids, ß2-agonists and diuretics—is highly urgent in order to free resources for new classes such as banned proteins ...
Georgakopoulos, C.G.+4 more
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Short stature, hyperkalemia and acidosis: A defect in renal transport of potassium [PDF]
Short stature, hyperkalemia, and acidosis: A defect in renal transport of potassium. An eleven-year-old boy presented with short stature, hyperkalemia, and metabolic acidosis. No endocrine cause for a short stature could be demonstrated.
Edelmann, Chester M.+3 more
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