Results 31 to 40 of about 5,666 (226)

Hyponatraemia and hypokalaemia due to indapamide [PDF]

open access: yes, 2002
The document attached has been archived with permission from the editor of the Medical Journal of Australia (10 January 2008). An external link to the publisher’s copy is included.Objectives: To review Australian adverse drug reaction reports describing ...
Chapman, M.   +3 more
core   +1 more source

Thermodynamic and experimental analysis of drug nanoparticles preparation using supercritical thermal processing: Solubility of Chlorothiazide in different Co-solvents

open access: yesCase Studies in Thermal Engineering, 2023
Background/purpose: Chlorothiazide is a well-known diuretic and an antihypertensive drug with poor solubility and permeability and thus low bioavailability.
Ahmad J. Obaidullah
doaj  

Selective effect of thiazides on the human osteoblast-like cell line MG-63 [PDF]

open access: yes, 1996
Selective effect of thiazides on the human osteoblast-like cell line MG-63. Thiazide diuretics have been shown to decrease bone-loss rate and to improve bone mineral density in patients using this medication.
Aubin, R.   +2 more
core   +1 more source

Experimental measurement and thermodynamic modeling of Chlorothiazide solubility in supercritical carbon dioxide

open access: yesCase Studies in Thermal Engineering, 2023
Chlorothiazide, with the brand name Diuril, is used as a diuretic as well as an antihypertensive drug. This medicine with very slight solubility in water and low permeability is categorized in the class IV of Biopharmaceutical Classification System (BCS)
Mohammed Majrashi   +5 more
doaj  

Comparative study of Two In Vitro Methods for Assessing Drug Absorption: Sartorius SM 16750 Apparatus Versus Everted Gut Sac

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2011
– Purpose. Oral drug administration remains the most common and most convenient way used in clinical therapy. The availability of a simple, rapid, economic and reproducible in vitro method to assess drug absorption is a very helpful tool.
Mohamed Ali Lassoued   +2 more
doaj   +1 more source

Impact of alternative solid state forms and specific surface area of high-dose, hydrophilic active pharmaceutical ingredients on tabletability [PDF]

open access: yes, 2013
YesIn order to investigate the effect of using different solid state forms and specific surface area (TBET) of active pharmaceutical ingredients on tabletability and dissolution performance, the mono- and dihydrated crystalline forms of ...
Abdul Jaleel O. W.   +30 more
core   +1 more source

Impact of process variables on the micromeritic and physicochemical properties of spray-dried microparticles, part II: physicochemical characterisation of spray-dried materials [PDF]

open access: yes, 2012
YesObjectives  In this work we investigated the residual organic solvent content and physicochemical properties of spray-dried chlorothiazide sodium (CTZNa) and potassium (CTZK) salts.
Al-Obaidi   +28 more
core   +1 more source

Use of Chlorothiazide in the Management of Central Diabetes Insipidus in Early Infancy

open access: yesCase Reports in Pediatrics, 2017
Management of central diabetes insipidus in infancy is challenging. The various forms of desmopressin, oral, subcutaneous, and intranasal, have variability in the duration of action.
Manish Raisingani   +2 more
doaj   +1 more source

Generic sample preparation combined with high-resolution liquid chromatography- time-of-flight mass spectrometry for unification of urine screening in doping-control laboratories [PDF]

open access: yes, 2010
A unification of doping-control screening procedures of prohibited small molecule substances—including stimulants, narcotics, steroids, ß2-agonists and diuretics—is highly urgent in order to free resources for new classes such as banned proteins ...
Georgakopoulos, C.G.   +4 more
core   +3 more sources

Short stature, hyperkalemia and acidosis: A defect in renal transport of potassium [PDF]

open access: yes, 1973
Short stature, hyperkalemia, and acidosis: A defect in renal transport of potassium. An eleven-year-old boy presented with short stature, hyperkalemia, and metabolic acidosis. No endocrine cause for a short stature could be demonstrated.
Edelmann, Chester M.   +3 more
core   +1 more source

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