Analysis of Pharmacokinetic and Pharmacodynamic Interactions Between Chlorpromazine and Risperidone via Simultaneous Measurement of Multiple Receptor Occupancy in the Rat Brain [PDF]
BiomedicinesBackground/Objectives: Combination therapy for schizophrenia may exacerbate side effects mediated by multiple brain receptors. This study aimed to elucidate the pharmacodynamic and pharmacokinetic interactions between chlorpromazine and risperidone.
Gaku Akashita +3 more
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Chlorpromazine-tadalafil interaction leading to refractory ischemic priapism and penile prosthesis implantation: a case report [PDF]
Basic and Clinical AndrologyBackground Priapism represents a rare urological emergency characterized by persistent penile erection unrelated to sexual stimulation. Although chlorpromazine-induced priapism has been documented, the synergistic interaction with phosphodiesterase type ...
Can Arici +4 more
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Evaluation of the use of chlorpromazine for agitation in pediatric patients [PDF]
Mental Health Clinician, 2023 Introduction: Chlorpromazine is a first-generation antipsychotic used for behavioral problems in pediatric patients. However, other therapies may demonstrate both improved outcomes and fewer side effects.
Rajwoana Ahmed, PharmD +4 more
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Kufa Journal for Veterinary Medical Sciences, 2021 The goal of this study was to assess the pain-relieving action of tramadol alone or when administered with chlorpromazine and screening for analgesic effects by using sedative non-analgesic doses of tramadol and chlorpromazine when injected together in
Manahel Allawi Abdulla Aljbori +2 more
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Frontiers in Oncology, 2021 The extremely poor prognosis of patients affected by glioblastoma (GBM, grade IV glioma) prompts the search for new and more effective therapies. In this regard, drug repurposing or repositioning can represent a safe, swift, and inexpensive way to bring ...
S. Matteoni +9 more
semanticscholar +1 more source
Coated Wire and Multiwalled Carbon Nanotube Composite Coated Wire Sensors for Determination of Chlorpromazine Hydrochloride in Pharmaceutical Preparations. [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2014 fabrication and performance characteristics of novel potentiometric sensors for the determination of chlorpromazine hydrochloride are described. The proposed sensors include a coated copper wire sensor and a multiwalled carbon nanotube (MWCNT) composite ...
Riyadh M. Jihad +2 more
doaj +1 more source
Quincke-edema induced by chlorpromazine: About two cases
European Psychiatry, 2021 Introduction Quincke-edema has been specifically associated with using certain drugs including chlorpromazine as detailed through two clinical cases. Objectives Illustration of two clinical cases about angioedema induced by Chlorpromazine.
S. Brahim +4 more
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Borneo Journal of Pharmacy, 2021 Schizophrenia is a psychiatric disorder that requires antipsychotics therapy. Antipsychotics cause many side effects, including orthostatic hypotension.
Noor Cahaya +2 more
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Short–term effect of chlorpromazine and diazepam on blood plasma acetylcholinesterase activity in chicks [PDF]
Iraqi Journal of Veterinary Sciences, 2007 The response of blood plasma acetylcholinestrase to acute administration of chlorpromazine and diazepam was examined in chick. Chlorpromazine in a dose–dependent manner at 25, 50, and 75 mg/Kg, subcutaneously inhibited the activity of Ache in the blood ...
L .K. Yacoub
doaj +1 more source
Repurposing chlorpromazine to treat COVID-19: The reCoVery study
L'Encephale, 2020 Objectives The ongoing COVID-19 pandemic has caused approximately 2,350,000 infections worldwide and killed more than 160,000 individuals. In Sainte-Anne Hospital (GHU PARIS Psychiatrie & Neuroscience, Paris, France) we have observed a lower incidence of
M. Plaze +8 more
semanticscholar +1 more source