Chlorpromazine for schizophrenia: a Cochrane systematic review of 50 years of randomised controlled trials [PDF]
Background Chlorpromazine (CPZ) remains one of the most common drugs used for people with schizophrenia worldwide, and a benchmark against which other treatments can be evaluated.
Borrill Jo+6 more
doaj +5 more sources
Beyond the Phenothiazine Core: Mechanistic Insights into the Three-Electron Oxidation of Chlorpromazine [PDF]
This study investigates the electrochemical oxidation mechanisms of chlorpromazine (CPZ), revealing a novel three-electron oxidation pathway that challenges the traditionally accepted two-electron paradigm, offering new insights into CPZ oxidation ...
Kiara T. Miller+2 more
doaj +2 more sources
Evaluation of the use of chlorpromazine for agitation in pediatric patients [PDF]
Introduction: Chlorpromazine is a first-generation antipsychotic used for behavioral problems in pediatric patients. However, other therapies may demonstrate both improved outcomes and fewer side effects.
Rajwoana Ahmed, PharmD+4 more
doaj +1 more source
The goal of this study was to assess the pain-relieving action of tramadol alone or when administered with chlorpromazine and screening for analgesic effects by using sedative non-analgesic doses of tramadol and chlorpromazine when injected together in
Manahel Allawi Abdulla Aljbori+2 more
doaj +1 more source
Quincke-edema induced by chlorpromazine: About two cases
Introduction Quincke-edema has been specifically associated with using certain drugs including chlorpromazine as detailed through two clinical cases. Objectives Illustration of two clinical cases about angioedema induced by Chlorpromazine.
S. Brahim+4 more
doaj +1 more source
Coated Wire and Multiwalled Carbon Nanotube Composite Coated Wire Sensors for Determination of Chlorpromazine Hydrochloride in Pharmaceutical Preparations. [PDF]
fabrication and performance characteristics of novel potentiometric sensors for the determination of chlorpromazine hydrochloride are described. The proposed sensors include a coated copper wire sensor and a multiwalled carbon nanotube (MWCNT) composite ...
Riyadh M. Jihad+2 more
doaj +1 more source
Schizophrenia is a psychiatric disorder that requires antipsychotics therapy. Antipsychotics cause many side effects, including orthostatic hypotension.
Noor Cahaya+2 more
doaj +1 more source
Short–term effect of chlorpromazine and diazepam on blood plasma acetylcholinesterase activity in chicks [PDF]
The response of blood plasma acetylcholinestrase to acute administration of chlorpromazine and diazepam was examined in chick. Chlorpromazine in a dose–dependent manner at 25, 50, and 75 mg/Kg, subcutaneously inhibited the activity of Ache in the blood ...
L .K. Yacoub
doaj +1 more source
Intravenous chlorpromazine in the acute treatment of episodic tension-type headache: a randomized, placebo controlled, double-blind study [PDF]
Acute headache is a very frequent symptom, responsible for a significant percentage of caseload at primary care units and emergency rooms. Chlorpromazine is easily available in such settings.
Marcelo Eduardo Bigal+2 more
doaj +1 more source
Objectives: The present study was undertaken to test the comparative efficacy of chlorpromazine and risperidone in patients of schizophrenia in a tertiary care hospital of Maharashtra.
Amrita Prakash Singam+2 more
doaj +1 more source