BACKGROUND The differential effects of so-called 'first- and second generation' antipsychotic medications, when given in the first episode, on the long-term outcome of schizophrenia remain to be elucidated.
R. Girgis+8 more
semanticscholar +1 more source
Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label
The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong+11 more
wiley +1 more source
PRIAPISM INDUCED BY CHLORPROMAZINE
SUMMARYPriapism is a pathologically prolonged and painful penile erection, usually unassociated with sexual desire or intercourse. Causes include certain oral medications, although the mechanism for drug‐induced priapism is unknown. We describe two cases of priapism attributed to chlorpromazine who have presented within the past two years.
Gokalp, A+4 more
openaire +3 more sources
Bacterial cell walls (CWs) extracted from Porphyromonas gingivalis are nanofabricated to form the CW vesicles (CWV), which have intrinsic peroxidase‐mimicking and sonodynamic activities due to the presence of µ‐oxo bisheme and meanwhile retain a large amount of lipopolysaccharide.
Meng Yang+9 more
wiley +1 more source
Effect of chlorpromazine on intact and irradiated aliquot ctdsDNA samples
Bagkground:Chlorpromazine is widely used in human medicine in the therapy of schizophrenia, organic psychosis and the manic phase of manic depressive illness. It expressed a selective cytotoxicity and the results of genotoxicity were positive. Objectives:
Ali M. Abbed+2 more
doaj
Comparison of intramuscular haloperidol and other short-acting injectable antipsychotics for management of acute agitation in an adult inpatient psychiatry unit [PDF]
Introduction There is no consensus on the optimal antipsychotic for acute agitation. Whereas haloperidol is frequently used and has proven efficacy, second generation antipsychotics show similar efficacy and improved safety and tolerability.
Sarah Gamcsik, PharmD+1 more
doaj +1 more source
Influence of chlorpromazine on renal histology of rats submitted to ischemia and reperfusion injury [PDF]
PURPOSE: To analyze the influence of chlorpromazine on renal histology of rats submitted to ischemia and reperfusion injury. METHODS: Sixteen Wistar rats - split in two groups - have been used: control group, receiving 3 mg/kg isotonic saline solution ...
Júlio César Foiatto+6 more
doaj +2 more sources
Construction of Active Sites‐Accessible Au8 Clusters for Intensive Tumor Pyroptosis
Ethynylferrocene (EFc) was utilized to engineer molecular‐like gold nanoclusters (NCs) with accessibly catalytic centers, resulting in NCs exhibiting excellent peroxidase‐like activity and the ability to radiosensitize, leading to the production of intracellular oxidative stress and activation of pyroptosis.
Qiu‐Xu Zang+8 more
wiley +1 more source
Interrater reliability of the modified Tinkertoy test: A validation study in schizophrenia and control groups. [PDF]
This study evaluated the interrater reliability of the modified Tinkertoy test (m‐TTT) in schizophrenia and control groups. Results demonstrated high reliability and highlighted the tool's potential for assessing cognitive deficits in clinical settings.
Nakamura Y+4 more
europepmc +2 more sources
Comparative effects of Rauwolfia vomitoria and chlorpromazine on social behaviour and pain
Background: Rauwolfia vomitoria has been used in Nigeria to manage psychiatric disorders despite orthodox medicine. Aims: This research was therefore aimed at comparing the effects of R.
S. Bisong, R. Brown, E. Osim
semanticscholar +1 more source