Results 11 to 20 of about 5,646 (214)

Spatial and Temporal Visualization of Polymorphic Transformations in Pharmaceutical Tablets. [PDF]

open access: yesAngew Chem Int Ed Engl
X‐ray Diffraction Computed Tomography (XRD‐CT) has been used to reveal pressure‐induced phase transformations in pharmaceutical tablets of glycolide as a function of compaction pressure. Temporal analysis of the tablets, and subsequent identification using electron diffraction, revealed a hydrolysis reaction occurred on storage of the tablets.
Gasol-Cardona J   +9 more
europepmc   +3 more sources

Hypoglycaemic coma with chlorpropamide [PDF]

open access: greenPostgraduate Medical Journal, 1967
C A Loehry   +2 more
openalex   +4 more sources

Olanzapine induced hyponatremia and rhabdomyolysis. [PDF]

open access: yesClin Case Rep, 2023
Abstract Rapid‐onset hyponatremia and rhabdomyolysis are rare, but potential, complications of olanzapine treatment. Hyponatremia, secondary to atypical antipsychotic use, has been reported in many case reports and is thought to be associated with an inappropriate antidiuretic hormone secretion syndrome.
Younes N   +5 more
europepmc   +2 more sources

Solids Turn into Liquids—Liquid Eutectic Systems of Pharmaceutics to Improve Drug Solubility

open access: yesPharmaceuticals, 2022
The low solubility of active pharmaceutical ingredients (APIs) is a problem in pharmaceutical development. Several methodologies can be used to improve API solubility, including the use of eutectic systems in which one of the constituents is the API ...
Mafalda C. Sarraguça   +3 more
doaj   +1 more source

Crystal structure of 4-bromo-N-(propylcarbamoyl)benzenesulfonamide

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2022
The title compound, C10H13BrN2O3S, 1, contains a sulfonyl urea moiety, which possesses potential therapeutic functions (e.g., anti-diabetic and herbicidal).
Mustafa Bookwala   +3 more
doaj   +1 more source

Halogen Bonding in Sulphonamide Co-Crystals: X···π Preferred over X···O/N?

open access: yesMolecules, 2023
Sulphonamides have been one of the major pharmaceutical compound classes since their introduction in the 1930s. Co-crystallisation of sulphonamides with halogen bonding (XB) might lead to a new class of pharmaceutical-relevant co-crystals. We present the
Tobias Heinen   +3 more
doaj   +1 more source

Simultaneous Quantification of Antidiabetic Agents in Human Plasma by a UPLC-QToF-MS Method. [PDF]

open access: yesPLoS ONE, 2016
An ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry method for the simultaneous quantification of chlorpropamide, glibenclamide, gliclazide, glimepiride, metformin, nateglinide, pioglitazone, rosiglitazone, and ...
Mariana Millan Fachi   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy