Results 11 to 20 of about 5,646 (214)
Spatial and Temporal Visualization of Polymorphic Transformations in Pharmaceutical Tablets. [PDF]
X‐ray Diffraction Computed Tomography (XRD‐CT) has been used to reveal pressure‐induced phase transformations in pharmaceutical tablets of glycolide as a function of compaction pressure. Temporal analysis of the tablets, and subsequent identification using electron diffraction, revealed a hydrolysis reaction occurred on storage of the tablets.
Gasol-Cardona J+9 more
europepmc +3 more sources
Chlorpropamide-alcohol flushing: a definition of its relation to non-insulin-dependent diabetes. [PDF]
David A. Pyke, R. D. G. Leslie
openalex +2 more sources
Hypoglycaemic coma with chlorpropamide [PDF]
C A Loehry+2 more
openalex +4 more sources
Olanzapine induced hyponatremia and rhabdomyolysis. [PDF]
Abstract Rapid‐onset hyponatremia and rhabdomyolysis are rare, but potential, complications of olanzapine treatment. Hyponatremia, secondary to atypical antipsychotic use, has been reported in many case reports and is thought to be associated with an inappropriate antidiuretic hormone secretion syndrome.
Younes N+5 more
europepmc +2 more sources
Solids Turn into Liquids—Liquid Eutectic Systems of Pharmaceutics to Improve Drug Solubility
The low solubility of active pharmaceutical ingredients (APIs) is a problem in pharmaceutical development. Several methodologies can be used to improve API solubility, including the use of eutectic systems in which one of the constituents is the API ...
Mafalda C. Sarraguça+3 more
doaj +1 more source
Crystal structure of 4-bromo-N-(propylcarbamoyl)benzenesulfonamide
The title compound, C10H13BrN2O3S, 1, contains a sulfonyl urea moiety, which possesses potential therapeutic functions (e.g., anti-diabetic and herbicidal).
Mustafa Bookwala+3 more
doaj +1 more source
Halogen Bonding in Sulphonamide Co-Crystals: X···π Preferred over X···O/N?
Sulphonamides have been one of the major pharmaceutical compound classes since their introduction in the 1930s. Co-crystallisation of sulphonamides with halogen bonding (XB) might lead to a new class of pharmaceutical-relevant co-crystals. We present the
Tobias Heinen+3 more
doaj +1 more source
Comparison of metformin and chlorpropamide in non-obese, maturity-onset diabetics uncontrolled by diet. [PDF]
B F Clarke, I W Campbell
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Simultaneous Quantification of Antidiabetic Agents in Human Plasma by a UPLC-QToF-MS Method. [PDF]
An ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry method for the simultaneous quantification of chlorpropamide, glibenclamide, gliclazide, glimepiride, metformin, nateglinide, pioglitazone, rosiglitazone, and ...
Mariana Millan Fachi+4 more
doaj +1 more source