Results 61 to 70 of about 4,532 (203)

Pharmacogenetic associations of MMP9 and MMP12 variants with cardiovascular disease in patients with hypertension.

PLoS ONE, 2011
ObjectivesMMP-9 and -12 function in tissue remodeling and may play roles in cardiovascular disease (CVD). We assessed associations of four MMP polymorphisms and three antihypertensive drugs with cardiovascular outcomes.MethodsHypertensives (n = 42,418 ...
Rikki M Tanner, Amy I Lynch, Victoria H Brophy, John H Eckfeldt, Barry R Davis, Charles E Ford, Eric Boerwinkle, Donna K Arnett   +7 more
doaj   +1 more source

Controlling Selectivity at the First Hydrogenation Level: Synthesis of 3‐Hydroxyisoindolines by Heterogeneously Silver‐Catalyzed Monohydrogenation of Phthalimides

Advanced Science, Volume 13, Issue 2, 9 January 2026.
3‐Hydroxylactams are obtained from phthalimides through a heterogeneous catalyzed chemoselective hydrogenation, able to stop the process at the first hydrogenation level. By using a rationally designed [Ag/Al2O3] recyclable solid nanocatalyst, a wide range of cyclic hemiamidals are accesed through a full atom‐economical reaction that preserves (hetero ...
Carles Lluna‐Galán, Rosa Adam, Jose R. Cabrero‐Antonino   +2 more
wiley   +1 more source

Effectiveness and safety of combining thiazides with loop diuretics vs. loop diuretics monotherapy in patients with acute decompensated heart failure: A retrospective cohort study

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 220-229, January 2026.
Aims This study investigated factors associated with and outcomes of combined loop diuretics with hydrochlorothiazide (HCTZ) for acute decompensated heart failure (ADHF). Methods In this retrospective study, adults hospitalized for ADHF and who received intravenous loop diuretics between January 2016 and March 2023 were enrolled.
Chia‐Chen Hsu, Hsien‐Chih Chiu, Ju‐Chieh Wung, Yueh‐Ching Chou, Yuh‐Lih Chang, Chian‐Ying Chou, Chin‐Chou Huang   +6 more
wiley   +1 more source

Clinical utility of azilsartan–chlorthalidone fixed combination in the management of hypertension

Vascular Health and Risk Management, 2012
Jerrica E Shuster,1,2 Barry E Bleske,1,2 Michael P Dorsch1,21University of Michigan Hospitals and Health Centers, Ann Arbor, MI, USA; 2College of Pharmacy, University of Michigan, Ann Arbor, MI, USAAbstract: Azilsartan–chlorthalidone fixed ...
Shuster JE, Bleske BE, Dorsch MP
doaj  

Circulating microRNA Biomarkers of Thiazide Response in Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Thiazide diuretics are the second most frequently prescribed class of antihypertensives, but up to 50% of patients with hypertension have minimal antihypertensive response to thiazides.
Lakshmi Manasa S. Chekka, Marwa Tantawy, Taimour Langaee, Danxin Wang, Rolf Renne, Arlene B. Chapman, John G. Gums, Eric Boerwinkle, Rhonda M. Cooper‐DeHoff, Julie A. Johnson   +9 more
doaj   +1 more source

Differential Effects of Antihypertensive Drug Classes on Home and Office Blood Pressure Variability

International Journal of Hypertension, Volume 2026, Issue 1, 2026.
Objective Blood pressure (BP) variability provides prognostic information beyond mean BP. However, the class‐specific associations of antihypertensive medications with BP variability remain uncertain, and few studies have directly contrasted home and office BP variability within the same patients while accounting for the white‐coat effect. Methods In a
Dong-Hyuk Cho, Mi-Na Kim, Jung-Joon Cha, Se Won Oh, Jae Hyoung Park, Kyung-Hee Cho, Seung Yong Shin, Eung Ju Kim, Hyung Joon Joo, Sreeja Dattachoudhury   +9 more
wiley   +1 more source

Quantification of Chlorthalidone in Bulk and Pharmaceutical Dosage form by UV, Infrared Spectrophotometry and Spectrofluorimetry. [PDF]

, 2014
The present study Chlorthalidone is an official drug of IP/BP and USP , Review of literature indicates that several methods have been reported for the estimation of chlorthalidone by UV-Visible spectrophotometric and RP-HPLC.
Senthilkumar, I
core  

Dose response to chlorthalidone in patients with mild hypertension; Efficacy of a lower dose

, 1978
A multicenter study of chlorthalidone was performed to determine the relative antihypertensive efficacy and side effects of doses lower than those usually recommended for therapy.
Burton, Zeb C, Bolton, Sanford M, Oster, James R, Michael, Ulrich F, Materson, Barry J, Stambaugh, John E, Morledge, John   +6 more
core   +1 more source

A Comprehensive Review on the Efficacy of Antihypertensives in Patients With End‐Stage Renal Disease

International Journal of Hypertension, Volume 2026, Issue 1, 2026.
End‐stage renal disease (ESRD) patients are particularly susceptible to hypertension, as blood pressure (BP) dysregulation leads to increased mortality and morbidity, especially considering the heightened risk of cardiovascular complications, including myocardial infarction, stroke, and congestive heart failure. Given the lack of specific guidelines on
Oluwakorede Akele, Nnedindu Asogwa, Gennifer Wahbah Makhoul, Khalil El-Gharib, Joanne Ling, Alaukika Agarwal, Vanessa Agberien, Ngowari Pokima, Thomas Gut, Suzanne El-Sayegh, Nidhi Chaudhary   +10 more
wiley   +1 more source

Fibroids in obstructed hemivagina and ipsilateral renal anomaly‐like syndrome: Successful hysterectomy and vaginal septoplasty in a kidney transplant recipient with uterus didelphys, vaginal septum and renal agenesis

International Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 491-493, July 2026.
Mariana Correia Moreira Cruz, Sophia Helena Batalha, Vitor Matheus Silva, Marcos de Lorenzo Messina, José Maria Soares Junior, Edmund Chada Baracat   +5 more
wiley   +1 more source