Results 1 to 10 of about 2,503,941 (405)
Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Synthesis [PDF]
Biotechnology Journal, 2018 Chinese hamster ovary (CHO) cells comprise a variety of lineages including CHO-DXB11, CHO-K1, CHO-DG44, and CHO-S. Despite all CHO cell lines sharing a common ancestor, extensive mutagenesis, and clonal selection has resulted in substantial genetic heterogeneity among them.
Renate Kunert +9 more
openaire +4 more sources
Cho and Pak reply to Lamm et al. comment on "A Convergent Series for the QED Effective Action" [PDF]
Phys.Rev.Lett. 91 (2003) 039101, 2003 Cho and Pak reply to Lamm et al. [hep-th/0007108] comment on "A Convergent Series for the Effective Action of QED" [hep-th/0006057].
D. G. Pak, Y. M. Cho
arxiv +3 more sources
Elucidation of the CHO Super-Ome (CHO-SO) by Proteoinformatics [PDF]
Journal of Proteome Research, 2015 Chinese hamster ovary (CHO) cells are the preferred host cell line for manufacturing a variety of complex biotherapeutic drugs including monoclonal antibodies. We performed a proteomics and bioinformatics analysis on the spent medium from adherent CHO cells.
Kelley M. Heffner +11 more
openaire +4 more sources
Low‐Carbohydrate Diet Exacerbates Denervation‐Induced Atrophy of Rat Skeletal Muscle Under the Condition of Identical Protein Intake [PDF]
Journal of Cachexia, Sarcopenia and MuscleBackground While decreased protein intake is associated with muscle mass loss, it is unclear whether a decrease in carbohydrate intake adversely affects muscle atrophy independently of protein intake.
Aki Yokogawa +9 more
doaj +2 more sources
Gravitating Cho–Maison monopole [PDF]
The European Physical Journal C, 2021 AbstractWe study numerical solutions corresponding to spherically symmetric gravitating electroweak monopole and magnetically charged black holes of the Einstein–Weinberg–Salam theory. The gravitating electroweak monopole solutions are quite identical to the gravitating monopole solution in SU(2) Einstein–Yang–Mills–Higgs theory, but with distinctive ...
Wong, Khai-Ming +2 more
openaire +3 more sources
Process development for Trastuzumab production from Chinese Hamster Ovary (CHO) in laboratory scale
Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ, 2022 Background: CHO cells have been commonly used in the production of recombinant protein. It is reported that around 70% recombinant therapeutic proteins are produced in CHO cells systems and the market size exceed 15£ billion per year.
Nguyễn Quang Huy +8 more
doaj +1 more source
mAbs, 2022 With the aim of increasing protein productivity of Chinese hamster ovary (CHO) cells, we sought to generate new CHO hosts with favorable biomanufacturing phenotypes and improved functionality.
Lina Chakrabarti +10 more
doaj +1 more source
Strategy for Developing a Stable CHO Cell Line that Produces Large Titers of Trastuzumab Antibody
Frontiers in Bioscience-Elite, 2023 Background: Trastuzumab (Herceptin®) is currently the main treatment option for breast cancer patients that overexpress the human epidermal growth factor receptor 2 (HER2). This antibody binds specifically to HER2, blocks cancer cell growth, and promotes
Hafsa Boulenouar +6 more
doaj +1 more source
Frontiers in Oncology, 2022 PurposesThe purpose of this study was to explore the diagnostic performance of Cho peak area (Cho Are), Cho peak amplitude (Cho Amp), and the combined approach (Cho Are_Amp) in detecting rabbit VX2 liver cancer at the early stage via hydrogen-1 proton ...
Ruikun Liao +16 more
doaj +1 more source
β-Hydroxybutyrate Oxidation in Exercise Is Impaired by Low-Carbohydrate and High-Fat Availability
Frontiers in Medicine, 2021 Purpose: In this study, we determined ketone oxidation rates in athletes under metabolic conditions of high and low carbohydrate (CHO) and fat availability.Methods: Six healthy male athletes completed 1 h of bicycle ergometer exercise at 75% maximal ...
David J. Dearlove +12 more
doaj +1 more source