Results 101 to 110 of about 11,449,307 (399)
Apolipoprotein E delivery by peritoneal implantation of encapsulated recombinant cells improves the hyperlipidaemic profile in apoE-deficient mice [PDF]
, 2005 Plasma apolipoprotein E (apoE) is a 34-kDa polymorphic protein which has atheroprotective actions by clearing remnant lipoproteins and sequestering excess cellular cholesterol.
Diakonov, IA +7 more
core
Hyaluronan reduces migration and proliferation in CHO cells
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2001 Expression of the hyaluronan synthase gene in hyaluronan-deficient CHO cells changed the cell morphology from a spindle shape to a flattened epithelial-type form. Hyaluronan producing CHO cells showed reduced initial cell adhesion, migration, proliferation and density at contact inhibition, but no difference in random migration determined by the Boyden
Birgit Dübe +3 more
openaire +3 more sources
Editorial: On the cusp of rational CHO cell engineering [PDF]
Biotechnology Journal, 2015 With the emergence of additional data on genomic variants, a more detailed molecular understanding of cellular processes and enhanced capabilities in fine-tuned manipulation of cell behaviour, the coming years promise to be exciting game changers in the production of therapeutics in mammalian cells.
Nielsen, Lars, Borth, Nicole
openaire +4 more sources
Making Photoresponsive Metal–Organic Frameworks an Effective Class of Heterogeneous Photocatalyst
Advanced Functional Materials, EarlyView.This review summarizes photoresponsive MOFs for photocatalytic applications, focusing on their capacity to enhance light harvesting, charge transfer, and surface reactions. While existing studies provide foundational insights, emerging characterization techniques enable a deeper understanding of photoresponsive MOFs.
Rui Liu +3 more
wiley +1 more source
Intracellular boron accumulation in CHO-K1 cells using amino acid transport control [PDF]
, 2014 BPA used in BNCT has a similar structure to some essential amino acids and is transported into tumor cells by amino acid transport systems. Previous study groups have tried various techniques of loading BPA to increase intracellular boron concentration ...
Isobe Tomonori +15 more
core +1 more source
Semi-supervised Cell Detection in Time-lapse Images Using Temporal Consistency [PDF]
arXiv, 2021 Cell detection is the task of detecting the approximate positions of cell centroids from microscopy images. Recently, convolutional neural network-based approaches have achieved promising performance. However, these methods require a certain amount of annotation for each imaging condition.
arxiv
Inter‐Layer Diffusion of Excitations in 2D Perovskites Revealed by Photoluminescence Reabsorption
Advanced Functional Materials, EarlyView.Inter‐layer diffusion of photoexcitations is monitored in thin films of the 2D perovskite (PEA)2PbI4 by tracking time‐dependent changes in photoluminescence spectra induced by photon reabsorption effects. A low out‐of‐plane excitation diffusion coefficient of 0.26 × 10−4 cm2 s−1 is determined through 1D diffusion modeling.
Jiaxing Du +7 more
wiley +1 more source
Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells
mAbs, 2015 Linking the heavy chain (HC) and light chain (LC) genes required for monoclonal antibodies (mAb) production on a single cassette using 2A peptides allows control of LC and HC ratio and reduces non-expressing cells.
Jake Chng +8 more
semanticscholar +1 more source
Frontiers in Physiology, 2016 Microcystin-LR (MC-LR) is a ubiquitous peptide that exhibits strong reproductive toxicity, although the mechanistic basis for such toxicity remains largely unknown.
Shenshen Zhang +7 more
doaj +1 more source
Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations
Advanced Functional Materials, EarlyView.Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou +2 more
wiley +1 more source