Results 11 to 20 of about 228,451 (311)

CHO-K1, COS7, and HEK293 cells express PAR1 and PAR2 receptors. [PDF]

open access: yes, 2020
A. CHO-K1, COS7, and HEK293 cells naturally express high levels of PAR1 and PAR2 mRNA but express little or no PAR3 and PAR4 mRNA. qPCR analysis was used to quantify the mRNA expression.
Chester Kuei (1660933)   +10 more
core   +1 more source

CHO microRNA engineering is growing up : recent successes and future challenges [PDF]

open access: yes, 2013
microRNAs with their ability to regulate complex pathways that control cellular behavior and phenotype have been proposed as potential targets for cell engineering in the context of optimization of biopharmaceutical production cell lines, specifically of
Grillari, Johannes   +12 more
core   +1 more source

Plasmodium vivax Gametocytes Adherence to Bone Marrow Endothelial Cells

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
In a Plasmodium vivax infection, it was shown a proportionally increased on gametocyte distribution within the bone marrow aspirant, suggesting a role of this organ as a reservoir for this parasite stage.
Luis Carlos Salazar Alvarez   +17 more
doaj   +1 more source

1H NMR Spectroscopy Profiling of Metabolic Reprogramming of Chinese Hamster Ovary Cells upon a Temperature Shift during Culture [PDF]

open access: yes, 2013
We report an NMR based approach to determine the metabolic reprogramming of Chinese hamster ovary cells upon a temperature shift during culture by investigating the extracellular cell culture media and intracellular metabolome of CHOK1 and CHO-S cells ...
Mark J. Howard (443860)   +14 more
core   +1 more source

GRP78 protects CHO cells from ribosylation [PDF]

open access: yes, 2018
D-Ribose (Rib), a reactive glycation compound that exists in organisms, abnormally increases in the urine of diabetic patients and can yield large amounts of advanced glycation end products (AGEs), leading to cell dysfunction. However, whether cellular
Lexiang Yu   +15 more
core   +1 more source

USING OF UNIVERSAL PLASMID CONSTRUCTIONS FOR DESIGN OF RECOMBINANT ANTIBODIES WITH DEFINED SPECIFICITY IN EUKARYOTIC CELLS

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. In this study we aimed to develop the methodology to change the antigen specificity of chimeric antibodies by replacing the variable region genes in the previously designed universal plasmid constructions pLK DT-17 and pHG DT-17 encoding the DT-17 ...
T. G. Samartseva   +5 more
doaj   +1 more source

Tumor anti-angiogenic gene therapy with microencapsulated recombinant CHO cells [PDF]

open access: yes, 2007
Microencapsulation of recombinant cells is a novel promising approach to tumor therapy in which therapeutic protein is sustainable and long-term delivered by microencapsulated cells.
Wang, Wei   +7 more
core   +1 more source

CD300LG improves the cytotoxic activity of CIK

open access: yesCentral European Journal of Immunology, 2017
To investigate the effect of CD300LG-γ induction on the cytotoxic activity of CIK. Eukaryotic expression plasmid hCD300LG-γ/pEGFP-C3, which can express human CD300LG-γ, was constructed and transfected into CHO cells by lipofectamine.
Qiuyue Wang   +6 more
doaj   +1 more source

Histamine H1 Receptor Down-Regulation Mediated by M3 Muscarinic Acetylcholine Receptor Subtype

open access: yesJournal of Pharmacological Sciences, 2004
Heterologous down-regulation of histamine H1 receptor (H1R) mediated by muscarinic acetylcholine receptor subtype was investigated using five kinds of Chinese hamster ovary (CHO) cells stably co-expressing the human H1R and one of the five (M1 –M5 ...
Katsuhiro Miyoshi   +5 more
doaj   +1 more source

Glycoproteomic Characterization of FUT8 Knock-Out CHO Cells Reveals Roles of FUT8 in the Glycosylation

open access: yesFrontiers in Chemistry, 2021
The α1,6-fucosyltransferase (encoded by FUT8 gene) is the key enzyme transferring fucose to the innermost GlcNAc residue on an N-glycan through an α-1,6 linkage in the mammalian cells.
Ganglong Yang   +5 more
doaj   +1 more source

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