Results 31 to 40 of about 228,451 (311)

Mannosylated chitosan nanoparticle–based cytokine gene therapy suppressed cancer growth in BALB/c mice bearing CT-26 carcinoma cells [PDF]

open access: yes, 2006
Cancer immunotherapy relies on the ability of the immune system to destroy tumor cells selectively and to elicit a long-lasting memory of such activity. Interleukin-12 (IL-12) is an immunomodulatory cytokine produced primarily by antigen-presenting cells,
Hyun Woo Kim   +9 more
core   +1 more source

Heparan sulfate and control of cell division: adhesion and proliferation of mutant CHO-745 cells lacking xylosyl transferase

open access: yesBrazilian Journal of Medical and Biological Research, 2001
We have examined the role of cell surface glycosaminoglycans in cell division: adhesion and proliferation of Chinese hamster ovary (CHO) cells.
C.R.C. Franco   +7 more
doaj   +1 more source

Invasion of CHO cells. [PDF]

open access: yes, 2013
A.) S. elongatus engineered with invasin and listeriolysin are able to invade CHO cells at a higher efficiency than S. elongatus harboring the empty vector or invasin alone.
Sean G. Megason (114231)   +6 more
core   +1 more source

The Era of Gene Therapy: The Advancement of Lentiviral Vectors and Their Pseudotyping

open access: yesViruses
Over 35 years of history, the field of gene therapy has undergone much progress. The initial concept—the replacement of dysfunctional genes with correct ones—has advanced to the next stage and reached the level of precise genome editing.
Bat-Erdene Jargalsaikhan   +2 more
doaj   +1 more source

Modulation of the Plasma Kallikrein-Kinin System Proteins Performed by Heparan Sulfate Proteoglycans

open access: yesFrontiers in Physiology, 2017
Human plasma kallikrein-kinin system proteins are related to inflammation through bradykinin. In the proximity of its target cells, high molecular weight kininogen (H-kininogen) is the substrate of plasma kallikrein, which releases bradykinin from H ...
Guacyara Motta, Ivarne L. S. Tersariol
doaj   +1 more source

Cell Apoptosis Induced by a Synthetic Carbazole Compound Lcy-2-Cho Is Mediated through Activation of Caspase and Mitochondrial Pathways [PDF]

open access: yes, 2009
The mechanisms involved in the apoptotic effect of LCY-2-CHO [9-(2- chlorobenzyl)-9H-carbazole-3-carbaldehyde], a synthetic carbazole derivative identified as an anti- inflammatory compound, were studied.
許銘仁;趙毅;張櫻馨;何豐名;黃麗嬌;林琬琬   +1 more
core   +1 more source

Cell surface glycoproteins of CHO cells

open access: yesExperimental Cell Research, 1986
Experimental Cell Research 165 (1986) 92-106. doi:10.1016/0014-4827(86)90535-5 ; Received by publisher: 1985-10-29 ; Harvest Date: 2016-01-04 12:19:39 ; DOI:10.1016/0014-4827(86)90535-5 ; Page Range: 92 ...
Thomas J. Raub, R.Michael Roberts
openaire   +2 more sources

Knockout of caspase-7 gene improves the expression of recombinant protein in CHO cell line through the cell cycle arrest in G2/M phase

open access: yesBiological Research, 2022
Background Chinese hamster ovary cell line has been used routinely as a bioproduction factory of numerous biopharmaceuticals. So far, various engineering strategies have been recruited to improve the production efficiency of this cell line such as ...
Fatemeh Safari, Bahman Akbari
doaj   +1 more source

The ratio of APP localized in lipid rafts was higher in the CHO PS1 ΔE9 cells than in the CHO PS1 WT cells. [PDF]

open access: yes, 2019
The CHO PS1 WT and ΔE9 cells were homogenized with sodium carbonate buffer as described in Methods. The cell lysates were used for discontinuous sucrose density gradients.
Sungkwon Chung (71502)   +4 more
core   +1 more source

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