Results 21 to 30 of about 4,711,608 (247)

CHO-K1, COS7, and HEK293 cells express PAR1 and PAR2 receptors.

, 2020
A. CHO-K1, COS7, and HEK293 cells naturally express high levels of PAR1 and PAR2 mRNA but express little or no PAR3 and PAR4 mRNA. qPCR analysis was used to quantify the mRNA expression.
Chester Kuei (1660933), Jennifer Towne (613222), Anthony Harrington (6505199), Changlu Liu (1660936), Lien Wang (3117306), Timothy Lovenberg (654883), Jiejun Wu (65346), Siquan Sun (2707435), Belinda Liu (8474187), Janise Deming (8474190), Grace Lee (409172)   +10 more
core   +1 more source

High Throughput miRNA Screening Identifies miR-574-3p Hyperproductive Effect in CHO Cells

Biomolecules, 2021
CHO is the cell line of choice for the manufacturing of many complex biotherapeutics. The constant upgrading of cell productivity is needed to meet the growing demand for these life-saving drugs.
Živa Švab, Luca Braga, Corrado Guarnaccia, Ivan Labik, Jeremias Herzog, Marco Baralle, Mauro Giacca, Nataša Skoko   +7 more
doaj   +1 more source

Microparticle-mediated transfer of the viral receptors CAR and CD46, and the CFTR channel in a CHO cell model confers new functions to target cells.

PLoS ONE, 2012
Cell microparticles (MPs) released in the extracellular milieu can embark plasma membrane and intracellular components which are specific of their cellular origin, and transfer them to target cells.
Gaëlle Gonzalez, Cyrielle Vituret, Attilio Di Pietro, Marc Chanson, Pierre Boulanger, Saw-See Hong   +5 more
doaj   +1 more source

Separation of CHO cells using hydrocyclones [PDF]

Cytotechnology, 2007
Hydrocyclones are simple and robust separation devices with no moving parts. In the past few years, their use in animal cell separation has been proposed. In this work, the use of different hydrocyclone configurations for Chinese hamster ovary (CHO) cell separation was investigated following an experimental design.
Rodrigo C V, Pinto, Ricardo A, Medronho, Leda R, Castilho   +2 more
openaire   +2 more sources

Heparan sulfate and control of cell division: adhesion and proliferation of mutant CHO-745 cells lacking xylosyl transferase

Brazilian Journal of Medical and Biological Research, 2001
We have examined the role of cell surface glycosaminoglycans in cell division: adhesion and proliferation of Chinese hamster ovary (CHO) cells.
C.R.C. Franco, H.A.O. Rocha, E.S. Trindade, I.A.N. Santos, E.L. Leite, S.S. Veiga, H.B. Nader, C.P. Dietrich   +7 more
doaj   +1 more source

Correction: Jargalsaikhan et al. The Era of Gene Therapy: The Advancement of Lentiviral Vectors and Their Pseudotyping. Viruses 2025, 17, 1036

Viruses
In the original publication [...]
Bat-Erdene Jargalsaikhan, Masanaga Muto, Masatsugu Ema   +2 more
doaj   +1 more source

Modulation of the Plasma Kallikrein-Kinin System Proteins Performed by Heparan Sulfate Proteoglycans

Frontiers in Physiology, 2017
Human plasma kallikrein-kinin system proteins are related to inflammation through bradykinin. In the proximity of its target cells, high molecular weight kininogen (H-kininogen) is the substrate of plasma kallikrein, which releases bradykinin from H ...
Guacyara Motta, Ivarne L. S. Tersariol
doaj   +1 more source

The Era of Gene Therapy: The Advancement of Lentiviral Vectors and Their Pseudotyping

Viruses
Over 35 years of history, the field of gene therapy has undergone much progress. The initial concept—the replacement of dysfunctional genes with correct ones—has advanced to the next stage and reached the level of precise genome editing.
Bat-Erdene Jargalsaikhan, Masanaga Muto, Masatsugu Ema   +2 more
doaj   +1 more source

Knockout of caspase-7 gene improves the expression of recombinant protein in CHO cell line through the cell cycle arrest in G2/M phase

Biological Research, 2022
Background Chinese hamster ovary cell line has been used routinely as a bioproduction factory of numerous biopharmaceuticals. So far, various engineering strategies have been recruited to improve the production efficiency of this cell line such as ...
Fatemeh Safari, Bahman Akbari
doaj   +1 more source

GRP78 protects CHO cells from ribosylation

, 2018
D-Ribose (Rib), a reactive glycation compound that exists in organisms, abnormally increases in the urine of diabetic patients and can yield large amounts of advanced glycation end products (AGEs), leading to cell dysfunction. However, whether cellular
Lexiang Yu, Wu, Beibei, Yang Lu, Y. Wei, Lu, Yang, Li, Juan, He, Rongqiao, Yan Wei, Rongqiao He, Hu, Pingdong, Wei, Yan, Juan Li, Pingdong Hu, R. He, Beibei Wu, Yu, Lexiang   +15 more
core   +1 more source