Results 261 to 270 of about 11,449,307 (399)

Antisense strategies for glycosylation engineering of Chinese hamster ovary (CHO) cells [PDF]

, 1998
E. Prati, Patrick Scheidegger, Adriana Sburlati, James E. Bailey   +3 more
openalex   +1 more source

Enhanced Catalytic Cycle of Glucose Oxidation and Reactive Species with ROS and RHS Generation Mediated by Galvanic Engineering of Dual Atomic Sites on Covalent Organic Frameworks Demonstrating Synergistic Bimetal Tumor Treatment

Advanced Science, EarlyView.
A galvanic replacement is used to control dual atomic metals (Au and Ir) on a covalent organic framework (COF) nanoparticle and then coated with hyaluronic acid (HA). Under a specific bimetallic ratio (COF/Aux/Ir1‐x), the optimization can be achieved for the conversion of intracellular nutrients into reactive species (HOCl and O2• ─) and effectively ...
Wei‐Chung Pan, Cheng‐Hung Luo, Wen‐Ling Lin, Liu‐Chun Wang, Divinah Manoharan, Po‐Ya Chang, Hwo‐Shuenn Sheu, Chen‐Hao Yeh, Chia‐Jui Yen, Chen‐Sheng Yeh   +9 more
wiley   +1 more source

High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional Positive Feedback Loop of Transactivator in CHO Cells. [PDF]

Cells, 2023
Ying B, Kawabe Y, Zheng F, Amamoto Y, Kamihira M.   +4 more
europepmc   +1 more source

Wogonin Attenuates Atherosclerosis via KLF11‐Mediated Suppression of PPARα‐YAP1‐Driven Glycolysis and Enhancement of ABCA1/G1‐Mediated Cholesterol Efflux

Advanced Science, EarlyView.
PPARα promotes KLF11 expression and recruits KLF11 and YAP1 to form a transcription complex, where KLF11 acts as a brake in PPARα‐YAP1‐mediated glycolysis. Wogonin reshapes the metabolism of macrophages from glycolysis to fatty acid oxidation via activation of the PPARα‐KLF11‐YAP1 pathway, by which wogonin reduces inflammation and foam cell formation ...
Chuanrui Ma, Yunqing Hua, Shu Yang, Yun Zhao, Wei Zhang, Yaodong Miao, Jing Zhang, Boxuan Feng, Guobin Zheng, Lan Li, Zhihao Liu, Han Zhang, Mingjun Zhu, Xiumei Gao, Guanwei Fan   +14 more
wiley   +1 more source

Optimization of a novel expression system for recombinant protein production in CHO cells. [PDF]

Sci Rep
Zhang J, Du C, Pan Y, Zhang Z, Feng R, Ma M, Wang T.   +6 more
europepmc   +1 more source

Engineering protein glycosylation in CHO cells to be highly similar to murine host cells. [PDF]

Front Bioeng Biotechnol, 2023
Gupta S, Shah B, Fung CS, Chan PK, Wakefield DL, Kuhns S, Goudar CT, Piret JM.   +7 more
europepmc   +1 more source

Resolving Artifacts in Voltage‐Clamp Experiments with Computational Modeling: An Application to Fast Sodium Current Recordings

Advanced Science, EarlyView.
Patch‐clamp experiments are fundamental to the measurement and understanding of ion currents that underlie physiological functions from neural activity to muscle contraction. Via a mathematical model of the experimental apparatus, this article highlights how artifact effects can be as large as some reported mutation and drug effects, and enables ...
Chon Lok Lei, Alexander P. Clark, Michael Clerx, Siyu Wei, Meye Bloothooft, Teun P. de Boer, David J. Christini, Trine Krogh‐Madsen, Gary R. Mirams   +8 more
wiley   +1 more source

Autophagy and Akt-Stimulated Cellular Proliferation Synergistically Improve Antibody Production in CHO Cells. [PDF]

Biotechnol J
Mao L, Sonbati SM, Schneider JW, Robinson AS.   +3 more
europepmc   +1 more source

Antigenicity and immunogenicity of SARS-CoV-2 surface glycoprotein fragment in CHO cells. [PDF]

Iran J Microbiol, 2023
Karimi S, Nazarian S, Sotoodehnejadnematalahi F, Dorostkar R, Amani J.   +4 more
europepmc   +1 more source

Transient Transfection with Glutamate-Cysteine Ligase (GLCL) cDNA Attenuates tert-Butyl Hydroperoxide (tBuOOH) Toxicity in Chinese Hamster Ovary (CHO) Cells [PDF]

, 1999
Caraciolo J. Fernandes, Lynette K. Rogers, Charles V. Smith   +2 more
openalex   +1 more source