Results 61 to 70 of about 11,449,307 (399)
Atomic vapor quantum memory for a photonic polarization qubit [PDF]
We report an experimental realization of an atomic vapor quantum memory for the photonic po- larization qubit. The performance of the quantum memory for the polarization qubit, realized with electromagnetically-induced transparency in two spatially separated ensembles of warm Rubidium atoms in a single vapor cell, has been characterized with quantum ...
arxiv +1 more source
To characterize a glutamine synthetase (GS)-based selection system, monoclonal antibody (mAb) producing recombinant CHO cell clones were generated by a single round of selection at various methionine sulfoximine (MSX) concentrations (0, 25, and 50 μM ...
S. Noh, Seunghyeon Shin, G. Lee
semanticscholar +1 more source
Clostridium perfringens epsilon toxin (Etx) is a pore forming toxin that causes enterotoxaemia in ruminants and may be a cause of multiple sclerosis in humans. To date, most in vitro studies of Etx have used the Madin-Darby canine kidney (MDCK) cell line.
Skye Marshall+6 more
doaj +1 more source
A fractal approach to the rheology of concentrated cell suspensions [PDF]
Results on the rheological behavior of novel CHO cell suspensions in a large range of concentrations are reported. The concentration dependent yield stress and elastic plateau modulus are formalized in the context of fractal aggregates under shear, and quite different exponents are found as compared to the case of red blood cell suspensions.
arxiv +1 more source
Metabolic engineering of CHO cells for the development of a robust protein production platform
Chinese hamster ovary (CHO) cells are the most preferred mammalian host used for the bio-pharmaceutical production. A major challenge in metabolic engineering is to balance the flux of the tuned heterogonous metabolic pathway and achieve efficient ...
Sanjeev Gupta+7 more
semanticscholar +1 more source
Establishment of a novel anti-TROP2 monoclonal antibody TrMab-29 for immunohistochemical analysis
TROP2 is a type I transmembrane glycoprotein originally identified in human trophoblast cells that is overexpressed in several types of cancer. To better understand the role of TROP2 in cancer, we herein aimed to develop a sensitive and specific anti ...
Yusuke Sayama+6 more
doaj
Recombinant therapeutic proteins (RTPs) are important parts of biopharmaceuticals. Chinese hamster ovary cells (CHO) have become the main cell hosts for the production of most RTPs approved for marketing because of their high-density suspension growth ...
Zheng-Mei Li+7 more
doaj +1 more source
Solving incompressible Navier--Stokes equations on irregular domains and quadtrees by monolithic approach [PDF]
We present a second-order monolithic method for solving incompressible Navier--Stokes equations on irregular domains with quadtree grids. A semi-collocated grid layout is adopted, where velocity variables are located at cell vertices, and pressure variables are located at cell centers.
arxiv +1 more source
Cloning of CHO Cells, Productivity and Genetic Stability—A Discussion
While many perceive mammalian cell culture-based manufacturing for biopharmaceuticals an established technology, numerous open questions remain to be solved.
F. Wurm, Maria J. Wurm
semanticscholar +1 more source
Objectives. To develop an effective technology for the cultivation of Chinese hamster ovary (CHO) cells stably producing GamP2C5 antibody which is a component I of the GamCoviMab candidate drug for emergency prevention and therapy of infection caused by
D. S. Polyansky+7 more
doaj +1 more source