Results 101 to 110 of about 3,708,398 (246)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

NARAL Flyer "Know the Facts: Misinformation in 12th & Delaware"

, 2010
Literature that corrects misspoken facts by anti-choice protestors in the movie 12th ...
NARAL Pro-Choice America
core  

A Public Choice Analysis of Digital Content Protection Policy: The Paradox of Technological Protection and Digital Regulation

This paper analyzes digital content protection policy from a public choice perspective. It examines how legal protection and public enforcement for digital content are determined.
Youngshin Kim, Korea Public Choice Association   +1 more
core   +1 more source

People are aware of the impact of defaults and use them strategically

Judgment and Decision Making
Decades of research in judgment and decision making highlight the significant impact of defaults, in which individuals tend to accept preselected options.
Omid Ghasemi, Ali Ghane-Ezabadi, Razieh Hojjat, Mahsa Afshin Mahjoub, Tohid Arastouy Irani, Elahe Gholampour, Moslem Solhirad, Ben R. Newell   +7 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Choice newsletter

, 1980
This a newsletter from Choice, the gay student union at Bowling Green State University in Ohio. It gives a description of the group, a calendar of upcoming events, information on support groups, and birthdays of ...
Choice
core  

How to Think Architecture: Inspirational Note to Architecture Students

, 2022
This bilingual book addresses both the Arabic speaker and international student in a methodic four-sectioned journey. It takes the reader from theory to practice by knocking on the doors of multiple architecture-related avenues.
Mohammed, Mohammed F. M., Ibrahim, Mohsen   +1 more
core  

Acceptability of workplace choice architecture modification for healthy behaviours. [PDF]

BMC Public Health, 2023
Rantala E, Vanhatalo S, Perez-Cueto FJA, Pihlajamäki J, Poutanen K, Karhunen L, Absetz P.   +6 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source