Results 111 to 120 of about 3,708,398 (246)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Catholics and abortion: notes on canon law. No. 1
Catholics for a Free Choice shapes and advances sexual and reproductive ethics that are based on justice, reflect a commitment to women’s well being, and respect and affirm the moral capacity of women and men to make sound decisions about their lives ...
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An experimental investigation into whether choice architecture interventions are considered ethical. [PDF]
Turetski D +4 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
These days, Home staging is one of the popular ways to change your place.
Stagers Choice (6181460)
core +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
The Choice Architecture of Choice Architecture: Toward a Non-Paternalistic Nudge Policy [PDF]
The paper seeks to recast the goal of nudge policy from a goal of achieving a specific result determined by government or by behavioral economists to a goal of giving individuals as much power as is practical to decide the choice architecture they face ...
Davind Colander, Andrew Qi Lin Chong
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Nurbsters, Foldsters and Neoplasmatic Architecture
Presented on February 20, 2012 from 6:00 pm-8:00 pm in the Reinsch-Pierce Family Auditorium on the Georgia Tech campus.Marcos Cruz is the Director of the Bartlett School of Architecture in London where he is also Studio Master of MArch Unit 20.
Cruz, Marcos
core +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
School of Architecture + Design reception, CAUS 50th anniversary
The original version of Fields + Array was exhibited at the Moss Arts Center then temporarily installed on Burchard Plaza. For the Architecture + Design reception, the concrete cylinders were recast, metal rods were inserted, and paper lanterns with self-
Ridgeway, Matthew +5 more
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