Results 191 to 200 of about 89,075 (280)

A Clinical Guidance for the Management of Patients With Hepatoid Adenocarcinoma and A Case Series

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor of non‐germ cell origin that morphologically resembles hepatocellular carcinoma (HCC). HAC has a propensity to metastasize to the liver and therefore may be mistaken for HCC. There is a lack of standardized treatment protocols, and further studies are needed to evaluate the benefit of ...
Christina Liava   +4 more
wiley   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li   +13 more
wiley   +1 more source

Clinical Relevance of Ratios Derived from Routine Blood-Based Biomarkers in Cholangiocarcinoma: A Retrospective Cohort Study. [PDF]

open access: yesMedicina (Kaunas)
Ventuneac AD   +6 more
europepmc   +1 more source

Surufatinib plus anti‐PD‐1/PD‐L1 antibody as second‐line therapy for advanced biliary tract cancer: A single‐centre investigator‐initiated trial

open access: yesClinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Abstract Objective To explore the efficacy and safety of surufatinib in combination with anti‐PD‐1/PD‐L1 antibodies (with or without chemotherapy) in patients with advanced BTC after failure of first‐line treatment. Methods 24 patients with advanced BTC who failed first‐line treatment were admitted to our centre from March 2023 to August 2024 and ...
Xinni Chen   +7 more
wiley   +1 more source

CEACAM6 silencing suppresses tumour growth and sensitises cholangiocarcinoma to cisplatin

open access: yesClinical and Translational Discovery, Volume 6, Issue 1, February 2026.
CEACAM6 has the potential to become a novel and independent prognostic biomarker in cholangiocarcinoma (CCA). Silencing CEACAM6 can inhibit CCA tumour growth and significantly enhance the chemosensitivity to cisplatin. This chemo‐sensitising effect is mediated through the disruption of ribosome biogenesis and impairment of DNA damage repair.
Shi‐Jia Dai   +8 more
wiley   +1 more source

Amino acid metabolic reprogramming: future prospects for cholangiocarcinoma therapy. [PDF]

open access: yesCell Death Discov
Hua S   +8 more
europepmc   +1 more source

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