Results 21 to 30 of about 27,028 (210)

Diagnostic and Prognostic Value of Circulating Cell-Free DNA for Cholangiocarcinoma

open access: yesDiagnostics, 2021
The analysis of cfDNA has been applied as a liquid biopsy in several malignancies. However, its value in the diagnosis and prognosis of cholangiocarcinoma (CCA) have not been well defined.
Preawwalee Wintachai   +10 more
doaj   +1 more source

Cold plasma endoscopy applied to biliary ducts: feasibility risk assessment on human-like and porcine models for the treatment of cholangiocarcinoma [PDF]

open access: yesJ. Phys. D. Appl. Phys., Vol. 55, No 45, 2022, 2023
For the past twelve years, cold plasmas have been positioned as a breakthrough technology for treating cancer thanks to their antitumor properties. The innovation of ad hoc plasma sources and personalized protocols appears crucial to treat cancers with a very poor prognosis.
arxiv   +1 more source

Establishment of a Potential Serum Biomarker Panel for the Diagnosis and Prognosis of Cholangiocarcinoma Using Decision Tree Algorithms

open access: yesDiagnostics, 2021
Potential biomarkers which include S100 calcium binding protein A9 (S100A9), mucin 5AC (MUC5AC), transforming growth factor β1 (TGF-β1), and angiopoietin-2 have previously been shown to be effective for cholangiocarcinoma (CCA) diagnosis.
Phongsaran Kimawaha   +6 more
doaj   +1 more source

Cold-atmospheric plasma induces tumor cell death in preclinical in vivo and in vitro models of human cholangiocarcinoma [PDF]

open access: yesCancers, 12, 1280, 2020, 2020
Through the last decade, cold atmospheric plasma (CAP) has emerged as an innovative therapeutic option for cancer treatment. Recently, we have set up a potentially safe atmospheric pressure plasma jet device that displays antitumoral properties in a preclinical model of cholangiocarcinoma (CCA), a rare and very aggressive cancer emerging from the ...
arxiv   +1 more source

Tumor budding may be a promising prognostic indicator in intrahepatic cholangiocarcinoma: A multicenter retrospective study

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 138-146, January 2023., 2023
High tumor budding is a new candidate for an additional determinant of the T category in staging ICC. An LCSGJ staging system containing an additional evaluation of tumor budding may lead to improved staging accuracy. Abstract Purpose This retrospective study evaluated our hypothesis that high tumor budding (≥10 buds) may help determine the appropriate
Hisashi Kosaka   +9 more
wiley   +1 more source

Metabolic Phenotyping Predicts Gemcitabine and Cisplatin Chemosensitivity in Patients With Cholangiocarcinoma

open access: yesFrontiers in Public Health, 2022
Gemcitabine and cisplatin serve as appropriate treatments for patients with cholangiocarcinoma (CCA). Our previous study using histoculture drug response assay (HDRA), demonstrated individual response patterns to gemcitabine and cisplatin.
Manida Suksawat   +41 more
doaj   +1 more source

Survival after surgery among patients with cholangiocarcinoma in Northeast Thailand according to anatomical and morphological classification

open access: yesBMC Cancer, 2021
Background Cholangiocarcinoma (CCA) has been categorized based on tumor location as intrahepatic (ICCA), perihilar (PCCA) or distal (DCCA), and based on the morphology of the tumor of the bile duct as mass forming (MF), periductal infiltrating (PI) or ...
Chaiwat Tawarungruang   +7 more
doaj   +1 more source

Targeting Fatty Acid Synthase Modulates Metabolic Pathways and Inhibits Cholangiocarcinoma Cell Progression

open access: yesFrontiers in Pharmacology, 2021
An aberrant regulation of lipid metabolism is involved in the pathogenesis and progression of cancer. Up-regulation of lipid biosynthesis enzymes, including acetyl-CoA carboxylase (ACC), fatty acid synthase (FASN) and HMG-CoA reductase (HMGCR), has been ...
Jittima Tomacha   +22 more
doaj   +1 more source

Anti-metastatic Potential of Natural Triterpenoid Cucurbitacin B Against Cholangiocarcinoma Cells by Targeting Src Protein

open access: yesIntegrative Cancer Therapies, 2022
Owing to the crucial role of Src in cancer metastasis, interruption of Src and its signaling has been considered a promising strategy for cancer metastasis treatment.
Putthaporn Kaewmeesri MS   +5 more
doaj   +1 more source

Curcumin-loaded nanocomplexes alleviate the progression of fluke-related cholangiocarcinoma in hamsters

open access: yesCancer Nanotechnology, 2023
Background Curcumin-loaded nanocomplexes (CNCs) previously demonstrated lower toxicity and extended release better than is the case for free curcumin. Here, we evaluated the efficacy of CNCs against opisthorchiasis-associated cholangiocarcinoma (CCA) in ...
Chanakan Jantawong   +11 more
doaj   +1 more source

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