Results 31 to 40 of about 142,420 (373)

Chemoembolization versus radioembolization for the treatment of unresectable intrahepatic cholangiocarcinoma in a single institution image-based efficacy and comparative toxicity [PDF]

, 2017
Aim: Compare radioembolization (Y90) and chemoembolization (CE) for the treatment of unresectable intrahepatic cholangiocarcinoma (UICC). Materials & methods: Institutional Review Board-approved, retrospective search was performed.
Akinwande, Olaguoke, Foltz, Gretchen, Mills, Abigail, Noda, Christopher, Saad, Nael, Shah, Veer, Weiner, Eric   +6 more
core   +2 more sources

Identification of tumor antigens and immune subtypes of cholangiocarcinoma for mRNA vaccine development

Molecular Cancer, 2021
The mRNA-based cancer vaccine has been considered a promising strategy and the next hotspot in cancer immunotherapy. However, its application on cholangiocarcinoma remains largely uncharacterized.
Xing Huang, Tianyu Tang, Gang Zhang, T. Liang   +3 more
semanticscholar   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Survival after surgery among patients with cholangiocarcinoma in Northeast Thailand according to anatomical and morphological classification

BMC Cancer, 2021
Background Cholangiocarcinoma (CCA) has been categorized based on tumor location as intrahepatic (ICCA), perihilar (PCCA) or distal (DCCA), and based on the morphology of the tumor of the bile duct as mass forming (MF), periductal infiltrating (PI) or ...
Chaiwat Tawarungruang, Narong Khuntikeo, Nittaya Chamadol, Vallop Laopaiboon, Jaruwan Thuanman, Kavin Thinkhamrop, Matthew Kelly, Bandit Thinkhamrop   +7 more
doaj   +1 more source

Liver: Intrahepatic cholangiocarcinoma [PDF]

, 2009
Review on Liver: Intrahepatic cholangiocarcinoma, with data on clinics, and the genes ...
Aishima, S, Enjoji, M
core   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

Targeting Fatty Acid Synthase Modulates Metabolic Pathways and Inhibits Cholangiocarcinoma Cell Progression

Frontiers in Pharmacology, 2021
An aberrant regulation of lipid metabolism is involved in the pathogenesis and progression of cancer. Up-regulation of lipid biosynthesis enzymes, including acetyl-CoA carboxylase (ACC), fatty acid synthase (FASN) and HMG-CoA reductase (HMGCR), has been ...
Jittima Tomacha, Jittima Tomacha, Hasaya Dokduang, Sureerat Padthaisong, Nisana Namwat, Nisana Namwat, Poramate Klanrit, Poramate Klanrit, Jutarop Phetcharaburanin, Jutarop Phetcharaburanin, Arporn Wangwiwatsin, Arporn Wangwiwatsin, Tueanjit Khampitak, Supinda Koonmee, Supinda Koonmee, Attapol Titapun, Attapol Titapun, Apiwat Jarearnrat, Apiwat Jarearnrat, Narong Khuntikeo, Narong Khuntikeo, Watcharin Loilome, Watcharin Loilome   +22 more
doaj   +1 more source

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

Anti-metastatic Potential of Natural Triterpenoid Cucurbitacin B Against Cholangiocarcinoma Cells by Targeting Src Protein

Integrative Cancer Therapies, 2022
Owing to the crucial role of Src in cancer metastasis, interruption of Src and its signaling has been considered a promising strategy for cancer metastasis treatment.
Putthaporn Kaewmeesri MS, Piman Pocasap PhD, Veerapol Kukongviriyapan PhD, Auemduan Prawan PhD, Sarinya Kongpetch PhD, Laddawan Senggunprai PhD   +5 more
doaj   +1 more source

Human liver flukes [PDF]

, 2017
Liver fluke infections occur in people worldwide. In some low-income regions, a combination of ecological, agricultural, and culinary factors leads to a very high prevalence of infection but, in higher-income regions, infections are uncommon.
Harrington, David, Lamberton, Poppy H.L., McGregor, Alastair   +2 more
core   +1 more source