Results 31 to 40 of about 26,929 (111)

Clinical pharmacokinetics of quinine and its relationship with treatment outcomes in children, pregnant women, and elderly patients, with uncomplicated and complicated malaria: a systematic review

Malaria Journal, 2022
Background Standard dosage regimens of quinine formulated for adult patients with uncomplicated and complicated malaria have been applied for clinical uses in children, pregnant women, and elderly.
Teerachat Saeheng, Kesara Na-Bangchang
doaj   +1 more source

Targeting Cholangiocarcinoma Cells By Cold Piezoelectric Plasmas: In Vitro Efficacy And Cellular Mechanisms [PDF]

Scientific Reports, Vol. 14, 30178, pp. 16 (2024)
Cold piezoelectric plasma (CPP) is a novel approach in cancer therapy, enabling the development of portable treatment devices capable of triggering cancer cell death. While its effectiveness remains underexplored, this research focuses on its application against cholangiocarcinoma (CCA), an aggressive cancer of the biliary tract.
arxiv   +1 more source

Identifying a unique chromosomal pattern to predict the gemcitabine response in patients with cholangiocarcinoma

Scientific Reports
Cholangiocarcinoma (CCA) is an epithelial bile duct cancer frequently found at an advanced stage, leading to poor response to current therapies. Although gemcitabine (GEM) and cisplatin (CIS) are the current gold-standard for treating unresectable CCA ...
Sutheemon Techa-ay, Sasithorn Watcharadetwittaya, Raksawan Deenonpoe, Prakasit Sa-ngiamwibool, Chanita Panwoon, Watcharin Loilome, Poramate Klanrit, Anchalee Techasen, Yaovalux Chamgramol, Manida Suksawat, Napat Armartmuntree, Thomas O’Connor, Hideyuki Saya, Malinee Thanee   +13 more
doaj   +1 more source

The Inhibition Kinetics and Potential Anti-Migration Activity of NQO1 Inhibitory Coumarins on Cholangiocarcinoma Cells

Integrative Cancer Therapies, 2019
Altered expression of a cytosolic flavoenzyme NAD(P)H:quinone oxidoreductase-1 (NQO1) has been seen in many human tumors. Its remarkable overexpression in cholangiocarcinoma (CCA; an aggressive malignancy of the biliary duct system) was associated with ...
Tueanjai Khunluck MS, Veerapol Kukongviriyapan PhD, Laddawan Senggunprai PhD, Wutthipong Duangarsong MS, Auemduan Prawan PhD   +4 more
doaj   +1 more source

Repeated praziquantel treatment and Opisthorchis viverrini infection: a population-based cross-sectional study in northeast Thailand

Infectious Diseases of Poverty, 2019
Background Opisthorchis viverrini infection is highly prevalent in northeast Thailand. This liver fluke is classified as a carcinogen due to its causal links with cholangiocarcinoma (CCA) development.
Kavin Thinkhamrop, Narong Khuntikeo, Paiboon Sithithaworn, Wilaiphorn Thinkhamrop, Kinley Wangdi, Matthew J. Kelly, Apiporn T. Suwannatrai, Darren J. Gray   +7 more
doaj   +1 more source

Primary liver cancer classification from routine tumour biopsy using weakly supervised deep learning [PDF]

JHEP Reports, Volume 6, Issue 3, 2024
The diagnosis of primary liver cancers (PLCs) can be challenging, especially on biopsies and for combined hepatocellular-cholangiocarcinoma (cHCC-CCA). We automatically classified PLCs on routine-stained biopsies using a weakly supervised learning method.
arxiv   +1 more source

Correction to: Repeated praziquantel treatment and Opisthorchis viverrini infection: a population-based cross-sectional study in northeast Thailand

Infectious Diseases of Poverty, 2019
In the original publication of this article [1], there is an error in the section of ‘Ethics approval and consent to participate’ at the end of the article, the correct Ethics reference number should be HE551404 rather than HE591067.
Kavin Thinkhamrop, Narong Khuntikeo, Paiboon Sithithaworn, Wilaiphorn Thinkhamrop, Kinley Wangdi, Matthew J. Kelly, Apiporn T. Suwannatrai, Darren J. Gray   +7 more
doaj   +1 more source

Lack of Targetable FGFR2 Fusions in Endemic Fluke-Associated Cholangiocarcinoma

JCO Global Oncology, 2020
PURPOSE Cholangiocarcinoma (CCA) remains a disease with poor prognosis and limited therapeutic options. Identification of driver genetic alterations may lead to the discovery of more effective targeted therapies.
Sarinya Kongpetch, Apinya Jusakul, Jing Quan Lim, Cedric Chuan Young Ng, Jason Yongsheng Chan, Vikneswari Rajasegaran, Tse Hui Lim, Kiat Hon Lim, Su Pin Choo, Simona Dima, Irinel Popescu, Dan G. Duda, Veerapol Kukongviriyapan, Narong Khuntikeo, Chawalit Pairojkul, Steven G. Rozen, Patrick Tan, Bin Tean Teh   +17 more
doaj   +1 more source

Selecting Regions of Interest in Large Multi-Scale Images for Cancer Pathology [PDF]

arXiv, 2020
Recent breakthroughs in object detection and image classification using Convolutional Neural Networks (CNNs) are revolutionizing the state of the art in medical imaging, and microscopy in particular presents abundant opportunities for computer vision algorithms to assist medical professionals in diagnosis of diseases ranging from malaria to cancer ...
arxiv  

Anticholangiocarcinoma activity and toxicity of the Kaempferia galanga Linn. Rhizome ethanolic extract

BMC Complementary and Alternative Medicine, 2017
Background Cholangiocarcinoma (CCA) is an important public health problem in several tropical and subtropical parts of the world particularly Thailand.
Asmare Amuamuta, Tullayakorn Plengsuriyakarn, Kesara Na-Bangchang   +2 more
doaj   +1 more source