Results 41 to 50 of about 128,690 (394)

Atmospheric pressure plasma jets applied to cancerology: correlating electrical configurations with in vivo toxicity and therapeutic efficiency [PDF]

Journal of Physics D: Applied Physics, Vol. 52, Issue 24, 2019, 2019
Two atmospheric pressure plasma jet devices - a plasma gun and a plasma Tesla jet - are compared in terms of safety and therapeutic efficiency to reduce the tumor volume progression of cholangiocarcinoma, i.e. a rare and very aggressive cancer emerging in biliary tree. For this, a three steps methodology is carried out.
arxiv   +1 more source

Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent Apoptosis, but are insensitive to direct activation with exogenous fas ligand [PDF]

, 2010
Introduction Cholangiocarcinoma is a rare malignancy of the biliary tract, the incidence of which is rising, but the pathogenesis of which remains uncertain.
A Bergamo, A Eliopoulos, A Ottaiano, A Pickens, AB Alexandroff, AH Klimp, AJ Baxendale, AM Cleary, AR Hayward, B Ansari, C Esche, D Wang, David H. Adams, DG Wingett, E Alabraba, E Bonfoco, E Jakobsen, Elizabeth H. Humphreys, F Mach, FG Que, G Pan, H Dzojic, H Le-Niculescu, HD Ochs, HR Shin, I Cascino, I Stamenkovic, J Ahmed-Choudhury, JL Ferrant, JR Maxwell, K Harada, Kevin T. Williams, KT Williams, LE French, M Fan, MC Rissoan, Mikhail V. Blagosklonny, MV Clement, N Itoh, P Angel, P Chu, P Starkel, P Watanapa, PA Lipsett, R Joplin, R Stewart, RH Vonderheide, RJ Armitage, RS Chapman, S Hess, S Kubo, S Paulie, SA Khan, SC Afford, SC Afford, SC Afford, SC Afford, Simon C. Afford, SM Abmayr, T Ohtsuka, T Shimonishi, T Suda, U Broome, U Bugajska, U Gaur, U Schonbeck, W Schuler, YS Zong   +67 more
core   +3 more sources

Preclinical studies of toxicity and anti-cholangiocarcinoma activity of the standardized capsule formulation of Atractylodes lancea (Thunb.) DC

BMC Complementary Medicine and Therapies, 2023
Background Cholangiocarcinoma (CCA), the adenocarcinoma of the biliary duct, is commonly reported in Asia, with the highest incidence in northeastern Thailand. Chemotherapy of CCA has been limited by the lack of effective chemotherapeutic drugs. A series
Tullayakorn Plengsuriyakarn, Kanawut Kotawong, Juntra Karbwang, Kesara Na-Bangchang   +3 more
doaj   +1 more source

H3 histamine receptor-mediated activation of protein kinase calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo [PDF]

, 2009
Histamine regulates functions via four receptors (HRH1, HRH2, HRH3, and HRH4). The D-myo-inositol 1,4,5-trisphosphate (IP(3))/Ca(2+)/protein kinase C (PKC)/mitogen-activated protein kinase pathway regulates cholangiocarcinoma growth.
A. Vetuschi, F. Y. Meng, FRANCHITTO, Antonio, G. Alpini, G. Carpino, GAUDIO, EUGENIO, H. Francis, J. Venter, M. White, MANCINELLI, ROMINA, ONORI, PAOLO, R. Sferra, S. Demorrow, S. Kopriva   +13 more
core   +1 more source

Cholangiocarcinoma: Epidemiology and risk factors

Liver international (Print), 2019
Cholangiocarcinoma (CCA) is a heterogeneous disease arising from a complex interaction between host‐specific genetic background and multiple risk factors.
Shahid A. Khan, S. Tavolari, G. Brandi
semanticscholar   +1 more source

Dose of intra‐operative opioids has no impact on recurrence or survival in primary liver cancer

Cancer Medicine, Volume 11, Issue 24, Page 4927-4934, December 2022., 2022
Kaplan‐meier curves for recurrence‐free and overall survial of high‐dose and low‐dose groups. No significant difference in recurrence‐free survial (A) or overall survial (B) after surgery was noted when comparing high‐dose with low‐dose groups. Abstract Background Intra‐operative use of opioid analgesics might have an impact on cancer recurrence and ...
Liuyuan Zhao, Lei Teng, Wenhui Zhang, Shiyan Lin, Xuejiao Liu, Junzhu Dai, Hongxue Shao, Xiaoshi Li, Quan Liu, Huichao Zou   +9 more
wiley   +1 more source

Associations between ultrasound screening findings and cholangiocarcinoma diagnosis in an at-risk population

Scientific Reports, 2022
The rate of cholangiocarcinoma (CCA) is increasing every year, especially in northeastern Thailand. Screening for CCA using ultrasonography (US) is the fastest technique to identify patients in early stage of CCA development.
Kavin Thinkhamrop, Narong Khuntikeo, Nittaya Chamadol, Apiporn T. Suwannatrai, Surachai Phimha, Matthew Kelly   +5 more
doaj   +1 more source

Diagnosis of Cholangiocarcinoma

Diagnostics, 2023
Cholangiocarcinoma (CCA), a tumor of the bile duct epithelium, is increasing in incidence. CCA remains a highly fatal malignancy because early diagnosis is difficult. Based on its anatomical location, CCA can be categorized into the following three groups: perihilar, intrahepatic, and extrahepatic.
Dong Woo Shin, Sung-Hoon Moon, Jong Hyeok Kim   +2 more
openaire   +3 more sources

Locoregional Treatments in Cholangiocarcinoma and Combined Hepatocellular Cholangiocarcinoma [PDF]

Cancers, 2021
Cholangiocarcinoma (CCA) is a primary and aggressive cancer of the biliary tree. Combined hepatocellular cholangiocarcinoma (CHC) is a distinctive primary liver malignancy which has properties of both hepatocytic and cholangiocytic differentiation.
Matteo Renzulli, Daryl Ramai, Jameel Singh, Samridhi Sinha, Nicolò Brandi, Anna Maria Ierardi, Elisa Albertini, Rodolfo Sacco, Antonio Facciorusso, Rita Golfieri   +9 more
openaire   +4 more sources

Mesenchymal stem cells: A novel treatment option for primary sclerosing cholangitis

Cell Biology International, Volume 47, Issue 2, Page 467-479, February 2023., 2023
Abstract Primary sclerosing cholangitis (PSC) is a progressive liver disease for which there is no effective therapy. Hepatocytes and cholangiocytes from a PSC patient were cocultured with mesenchymal stem cells (MSCs) to assess in vitro change. A single patient with progressive PSC was treated with 150 million MSCs via direct injection into the common
Amy L. Lightner, Neda Dadgar, Anil Vaidya, Robert Simon, Clifton Fulmer, Hassan Siddiki, K. V. Narayanan Menon, Peter Liu, R. Matthew Walsh   +8 more
wiley   +1 more source