Results 61 to 70 of about 39,125 (240)
Cholecystokinin-induced persistent stimulation of enzyme secretion from pancreatic acini
, 1981 When pancreatic acini are first incubated with cholecystokinin, washed to remove free cholecystokinin and then reincubated in fresh incubation solution, there is significant residual stimulation of amylase secretion.
R. T. Jensen +3 more
core +1 more source
Role of brain cholecystokinin in neuronal homeostasis: rediscovering novel functions of an old neuropeptide [PDF]
Exploration of Drug ScienceCholecystokinin (CCK) is the most prevalent neuropeptide in the brain, where it affects satiety, pain modulation, memory, and anxiety. Its effects are mediated by GPCRs known as the “alimentary (gastrointestinal)” CCK1r (CCK 1 receptor) and the brain ...
Santiago J. Ballaz
doaj +1 more source
Journal of Anatomy, EarlyView.The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva +19 more
wiley +1 more source
Cholecystokinin-induced contraction of dispersed smooth muscle cells
, 1982 Isolated smooth muscle cells were prepared from the fundus of guinea pig stomach by incubation with collagenase. Incubating the cells with the C-terminal octapeptide of cholecystokinin induced contraction, which was measured by micrometry and expressed ...
S. M. Collins, J. D. Gardner
core +1 more source
GLP‐1 receptor agonists and serious adverse events: Evidence, uncertainty and clinical implications
Journal of Internal Medicine, EarlyView.Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists provide benefits in weight reduction, glycaemic control in Type 2 diabetes, and cardiovascular and renal outcomes. Their widespread use has given rise to concerns regarding rare but potentially serious adverse events.
Peter Ueda
wiley +1 more source
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
Studies of cholecystokinin messenger RNA in rat lingual epithelium
, 1999 Cholecystokinin (CCK) is - a multifunctional peptide hormone that is widely distributedthroughout the body. Initially discovered as a gut hormone, CCK is important in integrating many digestive functions.
Crum, Barney
core
Carbobenzoxy amino acids: structural requirements for cholecystokinin receptor antagonist activity
, 1985 We used dispersed acini prepared from guinea pig pancreas to examine 28 carbobenzoxy (CBZ) amino acids for their abilities to function as cholecystokinin receptor antagonists. All amino acid derivatives tested, except for CBZ-alanine, CBZ-glycine, and N
R. T. Jensen +3 more
core +1 more source
Lipase inhibition attenuates the acute inhibitory effects of oral fat on food intake in healthy subjects [PDF]
, 2003 The lipase inhibitor, orlistat, is used in the treatment of obesity and reduces fat absorption by about 30%. However, the mean weight loss induced by orlistat is less than expected for the degree of fat malabsorption.
O'Donovan, D. +3 more
core +1 more source
Obesity Reviews, EarlyView.ABSTRACT Bariatric surgery (BS) has short‐ and medium‐term benefits in improving metabolic syndrome (MetS) components, but its long‐term impact remains incompletely characterized. This systematic review and meta‐analysis aimed to quantify the long‐term effects of BS (≥ 5 years) on fasting blood glucose (FBG), HDL cholesterol, triglycerides (TG), waist ...
Bernardo Paz Barboza +7 more
wiley +1 more source