Results 111 to 120 of about 18,704 (213)

Goldfish phoenixin: (I) structural characterization, tissue distribution, and novel function as a feedforward signal for feeding-induced food intake in fish model

Frontiers in Endocrinology
Phoenixin (PNX) is a novel peptide with diverse functions mediated by the orphan receptor GPR173. It also plays a role in appetite control, but the effect is not consistent across species and the mechanisms involved are still unclear. Using goldfish as a
Xiangfeng Qin, Cheng Ye, Ying Wai Chan, Anderson O. L. Wong   +3 more
doaj   +1 more source

GABA(B) receptor-mediated modulation of synaptic plasticity in the lateral amygdala [PDF]

, 2005
Fear conditioning, one of the most powerful and widely used methods to investigate the mechanisms of associative learning in animals, involves the pairing of an aversive stimulus such as a foot-shock (the unconditioned stimulus; US) with a neutral ...
Shaban, Hamdy
core   +1 more source

Control of physiologic glucose homeostasis via hypothalamic modulation of gluconeogenic substrate availability

Molecular Metabolism
Objectives: The brain mobilizes glucose in emergency situations such as hypoglycemia as well as during day-to-day physiology such as fasting. While most hypothalamic neuronal populations that contribute to glucose mobilization also contribute to other ...
Jiaao Su, Abdullah Hashsham, Nandan Kodur, Carla Burton, Amanda Mancuso, Anjan Singer, Jennifer Wloszek, Abigail J. Tomlinson, Warren T. Yacawych, Jonathan N. Flak, Kenneth T. Lewis, Lily R. Oles, Hiroyuki Mori, Nadejda Bozadjieva-Kramer, Adina F. Turcu, Ormond A. MacDougald, Martin G. Myers, Alison H. Affinati   +17 more
doaj   +1 more source

Establishment of a mouse model for injury-induced scar formation and the accompanying chronic pain: Comprehensive microarray analysis of molecular expressions in fibrosis and hyperalgesia

Molecular Pain, 2019
Background Surgery is often accompanied by scar formation, which results in a pathological state called fibrosis. Fibrosis is characterized by the excess deposition of extracellular matrix molecules in the connective tissue, leading to tissue contracture
Yuqiang Li, Hiroki Iida, Koji Kimata, Lisheng Zhuo, Akinobu Ota, Shinya Kimura, Xiaojian Yin, Masataka Deie, Takahiro Ushida   +8 more
doaj   +1 more source

Mécanismes de l'internalisation du récepteur CCK2 : bases pharmacologiques et structurales [PDF]

, 2011
Le récepteur CCK2 est un récepteur couplé aux protéines G (RCPG) possédant deux ligands naturels, la cholécystokinine et la gastrine, retrouvées au niveau du système nerveux central et du système gastro-intestinal. Le récepteur CCK2 est impliqué dans de
Magnan, Rémi
core  

Expression of the Cholecystokinin-B Receptor in Neoplastic Gastric Cells [PDF]

, 2017
Gastric cancer is an important disease due to its high mortality. Despite the decline in frequency, most cases are discovered late in its course, and most of the cancer patients die within a few years of diagnosis.
Mjønes, Patricia, Waldum, Helge, Nordrum, Ivar Skjåk, Sørdal, Øystein Finset, Sagatun, Liv, Sandvik, Arne Kristian, Fossmark, Reidar   +6 more
core  

Cholecystokinin facilitates motor skill learning by modulating neuroplasticity in the motor cortex

eLife
Cholecystokinin (CCK) is an essential modulator for neuroplasticity in sensory and emotional domains. Here, we investigated the role of CCK in motor learning using a single pellet reaching task in mice.
Hao Li, Jingyu Feng, Mengying Chen, Min Xin, Xi Chen, Wenhao Liu, Liping Wang, Kuan Hong Wang, Jufang He   +8 more
doaj   +1 more source

Effect of Cholecystokinin-B/Gastrin Receptor Antagonists on Rat Stomach ECL Cells [PDF]

, 1997
The histamine- and pancreastatin- containing ECL cells in the acid-producing mucosa of the rat stomach operate under the control of circulating gastrin. The present work examines how cholecystokinin (CCK)-B/gastrin receptors regulate the activity of the ...
Ding, Xi-Qin
core  

Proglumide, a Cholecystokinin Receptor Antagonist, Exacerbates b , b9 -Iminodipropionitrile-Induced Dyskinetic Syndrome in Rats [PDF]

, 1998
Proglumide, a cholecystokinin receptor antagonist, exacerbates b, b9 -iminodipropionitrile-induced dyskinetic syndrome in rats.NEUROTOXICOL TERATOL 20 (5) 571–579, 1998.—The present investigation was undertaken to study the effect of proglumide, a ...
Tariq, Mohammad, Al-Moutaery, Khalaf, Al-Deeb, Saleh, Rehana, Zehra, Khan, Haseeb Ahmad   +4 more
core  

Intestinal Gastrin/CCKBR Axis Protects against Type 2 Diabetes by Reducing Intestinal Glucose Absorption through the PI3K/Akt/eIF4B Signaling Pathway

Advanced Science
The Gastrin/CCKBR axis is essential for inhibiting intestinal sodium absorption, but its effects on intestinal glucose metabolism remain elusive. This study aims to determine the role of intestinal Gastrin/CCKBR on glucose absorption in the development ...
Xue Liu, Xing Liu, Yunpeng Liu, Anxiong Long, Wei Liu, Shiyun Sun, Shuaibing Lu, Xianxian Wu, Xiaodi Jia, Pedro A Jose, Qiang Wei, Xiaoliang Jiang, Haizeng Zhang, Zhiwei Yang   +13 more
doaj   +1 more source