Results 161 to 170 of about 18,704 (213)

Differential Expression of Gastrin, Cholecystokinin-A and Cholecystokinin-B Receptor mRNA in Human Pancreatic Cancer Cell Lines [PDF]

Scandinavian Journal of Gastroenterology, 2001
It has been assumed that gastrin stimulates the growth of pancreatic cancer in an autocrine way through co-expression of gastrin and the cholecystokinin-B receptor (CCK-BR). However, pancreatic cancer cell lines established directly from patients have revealed a great heterogeneity in cell proliferation when exposed to CCK, gastrin and their receptor ...
H J, Monstein, B, Ohlsson, J, Axelson
exaly   +4 more sources

Cholecystokinin- and cholecystokinin-B-receptor gene polymorphisms in panic disorder [PDF]

, 2004
Panic disorder like other neuropsychiatric disorders is believed to be caused by multiple psychosocial and biological factors. Several lines of evidence point to a role for the peptide neurotransmitter cholecystokinin in the pathogenesis of panic disorder.
V G, Hösing, A, Schirmacher, G, Kuhlenbäumer, C, Freitag, P, Sand, C, Schlesiger, C, Jacob, J, Fritze, P, Franke, M, Rietschel, H, Garritsen, M M, Nöthen, R, Fimmers, F, Stögbauer, J, Deckert   +14 more
core   +5 more sources

Radiolabeling approaches for cholecystokinin B receptor imaging [PDF]

Peptide Science, 2002
AbstractRegulatory peptides and their analogs are being extensively investigated as radiopharmaceuticals for cancer imaging. In particular, cholecystokinin (CCK) receptors of the subtype B (CCK‐BR) have been shown to be overexpressed in certain neuroendocrine tumors including medullary thyroid cancer.
ALOJ L., PANICO M. R., CARACÒ C., ZANNETTI A., DEL VECCHIO, SILVANA, DI NUZZO C., ARRA C., MORELLI, GIANCARLO, TESAURO, DIEGO, DE LUCA S., PEDONE C., SALVATORE, MARCO   +11 more
openaire   +7 more sources

Expression of Cholecystokinin-B/Gastrin Receptors in Medullary Thyroid Cancer [PDF]

The European Journal of Surgery, 1999
To characterise the cholecystokinin (CCK) receptor subtypes in medullary thyroid cancer by measuring the expression of CCK-A and CCK-B/gastrin receptor mRNA.Open study.Teaching hospital, Sweden.6 patients with medullary thyroid cancer.Pentagastrin stimulation test and measurement of calcitonin concentration. Biopsy specimens were analysed using reverse
A, Amiri-Mosavi, H, Ahlman, L E, Tisell, B, Wängberg, L, Kölby, E, Forssell-Aronsson, P A, Lundberg, G, Lindstedt, O, Nilsson   +8 more
openaire   +3 more sources

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Role of cholecystokinin-A and cholecystokinin-B receptors in anxiety

Amino Acids, 2002
Evidence from several laboratories indicates that the anxiogenic effects of cholecystokinin (CCK) are mediated by CCKB receptors. However, it has been reported that CCKA receptors have been found in brain and CCKA antagonists have anxiolytic properties.
A M, Hernandez-Gómez, R, Aguilar-Roblero, M, Pérez de la Mora   +2 more
openaire   +2 more sources

Cholecystokinin, cholecystokinin-A receptor and cholecystokinin-B receptor gene polymorphisms in Parkinson's disease

Pharmacogenetics, 2003
Cholecystokinin modulates the release of dopamine and dopamine-related behaviours in the mesolimbic pathway, where cholecystokinin and dopamine coexist in dopaminergic neurones. Because cholecystokinin and its receptors (A and B) have a functional interaction with dopaminergic neurotransmission, alterations in them may constitute a predisposition for ...
Jian, Wang, Yan-Mei, Si, Zhuo-Lin, Liu, Long, Yu   +3 more
openaire   +2 more sources

Cholecystokinin-A and Cholecystokinin-B/Gastrin Receptor mRNA Expression in the Gastrointestinal Tract and Pancreas of the Rat and Man: A Polymerase Chain Reaction Study [PDF]

Scandinavian Journal of Gastroenterology, 1996
BACKGROUND: Gastrin and cholecystokinin (CCK) are thought to exert trophic effects on the gastrointestinal tract and pancreas. Two types of receptors have been cloned, CCK-A and CCK-B/ gastrin.
Albert Salehi, I Lundquist, A G Nylander   +2 more
exaly   +2 more sources

Localization of cholecystokinin A and cholecystokinin B-gastrin receptors in the human stomach

Gastroenterology, 1997
Gastrin and cholecystokinin (CCK) are gut-brain peptides, with multiple functions in the gastrointestinal tract mediated through CCK-B-gastrin and CCK-A receptors. The receptor localization is, however, not well established in humans. The aim of this study was to investigate the distribution and pharmacological characteristics of CCK-A and CCK-B ...
Reubi JC, Waser B, Läderach U, Stettler C, Friess H, Halter F, Schmassmann A   +6 more
openaire   +3 more sources