Results 121 to 130 of about 77,065 (293)
Exploring the Single‐Cell Dynamics of FOXM1 Under Cell Cycle Perturbations
The varied FOXM1 dynamic patterns reveal significant differences in cellular responses to the same stimuli at the single‐cell level. This emphasises the relationship between cue, signal and response as influenced by different drug types and concentrations.
Tooba Jawwad+6 more
wiley +1 more source
Cholera Toxins: Immunogenicity of the Rabbit Ileal Loop Toxin and Related Antigens [PDF]
Jasbir Kaur, W. Burrows, Lora Cercavski
openalex +1 more source
Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder+4 more
wiley +1 more source
Back to the Future: Studying Cholera Pathogenesis Using Infant Rabbits
Cholera is a severe diarrheal disease, caused by Vibrio cholerae, for which there has been no reproducible, nonsurgical animal model. Here, we report that orogastric inoculation of V.
Jennifer M. Ritchie+3 more
doaj +1 more source
Abstract We previously developed the CellPhe toolkit, an open‐source R package for automated cell phenotyping from ptychography time‐lapse videos. To align with the growing adoption of python‐based image analysis tools and to enhance interoperability with widely used software for cell segmentation and tracking, we developed a python implementation of ...
Laura Wiggins+8 more
wiley +1 more source
Isolation of cholera toxins by dextran sulfate precipitation [PDF]
Stephen H. Richardson, David J. Evans
openalex +1 more source
ROLE OF CHOLERA TOXIN IN EXPERIMENTAL CHOLERA [PDF]
D. R. Kulkarni, M. V. Panse, N. K. Dutta
openaire +3 more sources
In Hyphomicrobium denitrificans, the use of thiosulfate as a supplemental electron donor is regulated by two homologous sulfane‐sulfur responsive ArsR‐type transcriptional repressors, sHdrR and SoxR, that act cooperatively. Remarkably, the regulation by sHdrR/SoxR extends far beyond sulfur oxidation and deeply affects anaerobic metabolism, particularly
Jingjing Li+3 more
wiley +1 more source
Reconstitution of cholera toxin-activated adenylate cyclase. [PDF]
Gary L. Johnson+2 more
openalex +1 more source
In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley +1 more source